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Pharmacology Chapters 1-13 exam
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Drug - ANSAny substance that is taken to cure, or reduce symptoms of a medical condition.

Pharmacology - ANSThe study of medicine.

Pharmacotherapy/Pharmacotherapeutics - ANSApplication of drugs for the purpose of disease
prevention and treatment of suffering.

Indications and Contraindications - ANSThe conditions for which a drug is approved are its
indications. Every drug has at least one indication. Some drugs are used for conditions for
which they have not been approved; these are called unlabeled or off- label indications.

Therapeutic classification - ANS-Based on their usefulness in treating a specific disease
-The key to therapeutic classification is to simply state what condition is being treated by the
particular drug.
-The prefix anti- refers to therapeutic classification.

Pharmacologic Classification - ANS-Addresses a drugs mechanism of action or how a drug
produces its effect in the body.
-More specific than therapeutic
-Requires biochemistry and pathophysiology

Chemical name - ANS-Assigned using standard nomenclature.
-A drug has only one chemical name
-Helpful in predicting a drugs physical and chemical properties.

Generic name - ANSName assigned by the United States Adopted Name Council.
Less complicated and easy to remember.

Trade Name - ANSSometimes called the proprietary product, or brand name is assigned by
the pharmaceutical company maketing the drug.

Exclusivity - ANSTypical length of exclusivity for a new drug is 5 years.

Combination drug - ANSDrugs with more than one active generic ingredient.

, Pros and Cons of Generic Drugs - ANSGeneric drugs are less expensive than brand name
drugs, by they may differ in bioavailability. (The rate at which drug produces its effect.)

The nurses responsibility for knowledge in regards to pharmacotherapeutics... - ANSIs what
drug is ordered including name and drug classification, intended or proposed used, effects on
the body, contraindications, special considerations (how age, weight, body fat distribution, and
pathophysiologic states affect pharmacotheraputic response), expected and potential adverse
events, why the drug was prescribed how the drug is supplied by the pharmacy, administration
of the drug, and what considerations apply to the patient.

The major goal to study pharmacology... - ANSis to eliminate medication errors and to limit the
number and severity of adverse drug events.

To prevent medication errors RN's can - ANSRoutinely apply their experience and knowledge
of pharmacotherapeutics to clinical practice. It is vital the nurse be prepared to cognized and
respond to potential adverse effects of the medication.

Pharmacotherapy and the older adult
(pharmokinetic and pharmodynamics). - ANSNormal aging processes can alter
pharmacokinetic and pharmacodynamics responses to drugs.

Pharmacotherapy and the older adult
(absorption) - ANSOverall, absorption of nutrients and drugs tend to slow with aging.

Pharmacotherapy and the older adult (plasma levels drug concentration in tissues) - ANSAge
related increases in fat storage cause lipid soluble drugs to be stored in the body for extended
periods, leading to lower plasma levels and increased drug concentrations in the tissues.

Age related changes in the liver - ANSInclude reduced hepatic function, decreased liver mass,
diminished blood flow, and alteration in the activity of hepatic enzymes.

Frequency of administration for older adults - ANSShould be decreased to avoid toxicity due to
drug accumulation.

Older adults and receptors - ANSPharmacodynamic changes are usually associated with drug
receptors. Evidence suggests that older adults have a decreased number of receptors.

The government agency that is responsible for regulating drugs in the United States. -
ANSFDA-Food and Drug Administration.
o Protect the public health.
o Speeding innovations that make medicines and food more effective.
o Helping the public get more accurate information.

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