MPJE (CONTROLLED SUBSTANCES)
EXAM 2025 QUESTIONS AND ANSWERS
In what schedule did DEA list carisoprodol products? - ANS IV
What changes can be made to Schedule II Prescriptions? - ANS date of issue - may be added
but not changed;
patient's address;
drug strength;
drug dosage form;
drug quantity - may be modified in conjunction with change in strength only, not to exceed the
original total dosage prescribed; and
directions for use.
What changes may not be made to Schedule II Prescriptions? - ANS name of the drug (except
to generic when appropriate)
name of the patient
signature of the practitioner.
Can a pharmacist change or add the correct amount of acetaminophen to a prescription for a
combination product containing a schedule II drug and acetaminophen? - ANS Yes
after speaking directly with the prescriber and documenting the clarification on the prescription
Are there any exemptions to Controlled Substance Reporting System requirements regarding
distribution of controlled substance samples? - ANS Yes
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,"A dispenser shall not be required to report instances in which a Schedule V non-narcotic, non-
anorectic Schedule V controlled substance is provided directly to the ultimate user for
the purpose of assessing a therapeutic response
when prescribed according to indications approved by the United States Food and Drug
Administration."
How must controlled substances maintained in a practitioner's office (as opposed to a
pharmacy) for dispensing or administration be stored? - ANS Locked cabinet or other secure
storage container with limited access by the office staff. FCSA
What is the NC Medical Board's position on the use of opiates to treat pain? - ANS Basically
there are no regulations but prescribers need to be careful.
http://www.ncmedboard.org/resources-information/professional-resources/laws-rules-
position-statements/position-
statements/Policy_for_the_use_of_opiates_for_the_treatment_of_pain.
Is it "legal" for a pharmacist to add a DEA number to a controlled substance prescription when
the prescriber omits that information? - ANS yes
Are pharmacists required to hand sign and date controlled substance prescriptions? - ANS no
May a prescribing practitioner prescribe other medications on a prescription that already
includes a Schedule II medication? - ANS yes
Can I fill Schedule II prescriptions bearing a "do not fill until" date? - ANS yes
What are the rules around issuance of multiple prescriptions for CIIs? - ANS (a) No CII refills
(b) Prescriber may issue multiple Rx's to provide (no more than a) 90 day supply
2 Copyright ©2025 SIRJOEL ALL RIGHTS RESERVED
, Common Sense Stuff:
(i) Each separate prescription is issued for a legitimate medical purpose by an individual
practitioner acting in the usual course of professional practice;
(ii) The individual practitioner provides written instructions on each prescription (other than the
first prescription, if the prescribing practitioner intends for that prescription to be filled
immediately) indicating the earliest date on which a pharmacy may fill each prescription;
(iii) The individual practitioner concludes that providing the patient with multiple prescriptions
in this manner does not create an undue risk of diversion or abuse;
(iv) The issuance of multiple prescriptions as described in this section is permissible under the
applicable state laws; and
(v) The individual practitioner complies fully with all other applicable requirements under the
Act and these regulations as well as any additional requirements under state law.
(2) Nothing in this paragraph (b) shall be construed as mandating or encouraging individual
practitioners to issue multiple prescriptions or to see their patients only once every 90 days
when prescribing Schedule II controlled substances. Rather, individual practitioners must
determine on their own, based on sound medical judgment, and in accordance with established
medical standards, whether it is appropriate to issue multiple prescriptions and how often to
see their patients when doing so.
What information must be reported under the controlled substance reporting act? - ANS (1)
Dispenser's AND Prescriber DEA number.
(2) Pt Name
Full address
Telephone number
Date of birth.
(3) Date writen
(4) Date filled.
(5) Rx number.
(6) Whether the prescription is new or a refill.
(7) Dispense quantity
(8) Days supply
3 Copyright ©2025 SIRJOEL ALL RIGHTS RESERVED
EXAM 2025 QUESTIONS AND ANSWERS
In what schedule did DEA list carisoprodol products? - ANS IV
What changes can be made to Schedule II Prescriptions? - ANS date of issue - may be added
but not changed;
patient's address;
drug strength;
drug dosage form;
drug quantity - may be modified in conjunction with change in strength only, not to exceed the
original total dosage prescribed; and
directions for use.
What changes may not be made to Schedule II Prescriptions? - ANS name of the drug (except
to generic when appropriate)
name of the patient
signature of the practitioner.
Can a pharmacist change or add the correct amount of acetaminophen to a prescription for a
combination product containing a schedule II drug and acetaminophen? - ANS Yes
after speaking directly with the prescriber and documenting the clarification on the prescription
Are there any exemptions to Controlled Substance Reporting System requirements regarding
distribution of controlled substance samples? - ANS Yes
1 Copyright ©2025 SIRJOEL ALL RIGHTS RESERVED
,"A dispenser shall not be required to report instances in which a Schedule V non-narcotic, non-
anorectic Schedule V controlled substance is provided directly to the ultimate user for
the purpose of assessing a therapeutic response
when prescribed according to indications approved by the United States Food and Drug
Administration."
How must controlled substances maintained in a practitioner's office (as opposed to a
pharmacy) for dispensing or administration be stored? - ANS Locked cabinet or other secure
storage container with limited access by the office staff. FCSA
What is the NC Medical Board's position on the use of opiates to treat pain? - ANS Basically
there are no regulations but prescribers need to be careful.
http://www.ncmedboard.org/resources-information/professional-resources/laws-rules-
position-statements/position-
statements/Policy_for_the_use_of_opiates_for_the_treatment_of_pain.
Is it "legal" for a pharmacist to add a DEA number to a controlled substance prescription when
the prescriber omits that information? - ANS yes
Are pharmacists required to hand sign and date controlled substance prescriptions? - ANS no
May a prescribing practitioner prescribe other medications on a prescription that already
includes a Schedule II medication? - ANS yes
Can I fill Schedule II prescriptions bearing a "do not fill until" date? - ANS yes
What are the rules around issuance of multiple prescriptions for CIIs? - ANS (a) No CII refills
(b) Prescriber may issue multiple Rx's to provide (no more than a) 90 day supply
2 Copyright ©2025 SIRJOEL ALL RIGHTS RESERVED
, Common Sense Stuff:
(i) Each separate prescription is issued for a legitimate medical purpose by an individual
practitioner acting in the usual course of professional practice;
(ii) The individual practitioner provides written instructions on each prescription (other than the
first prescription, if the prescribing practitioner intends for that prescription to be filled
immediately) indicating the earliest date on which a pharmacy may fill each prescription;
(iii) The individual practitioner concludes that providing the patient with multiple prescriptions
in this manner does not create an undue risk of diversion or abuse;
(iv) The issuance of multiple prescriptions as described in this section is permissible under the
applicable state laws; and
(v) The individual practitioner complies fully with all other applicable requirements under the
Act and these regulations as well as any additional requirements under state law.
(2) Nothing in this paragraph (b) shall be construed as mandating or encouraging individual
practitioners to issue multiple prescriptions or to see their patients only once every 90 days
when prescribing Schedule II controlled substances. Rather, individual practitioners must
determine on their own, based on sound medical judgment, and in accordance with established
medical standards, whether it is appropriate to issue multiple prescriptions and how often to
see their patients when doing so.
What information must be reported under the controlled substance reporting act? - ANS (1)
Dispenser's AND Prescriber DEA number.
(2) Pt Name
Full address
Telephone number
Date of birth.
(3) Date writen
(4) Date filled.
(5) Rx number.
(6) Whether the prescription is new or a refill.
(7) Dispense quantity
(8) Days supply
3 Copyright ©2025 SIRJOEL ALL RIGHTS RESERVED
