MSN-FNP 570 – Advanced Pathophysiology – Midterm Exam
Questions and Answers – Complete Study Material
This document contains a complete set of midterm exam questions and answers for the MSN-FNP 570
Advanced Pathophysiology course. It includes key topics such as ischemia, genetic mutations,
respiratory disorders, cardiovascular physiology, neurological conditions, and immune responses. The
material provides accurate and concise answers, making it a useful resource for preparation and review.
1. During ischemia, what effect does the loss of ATP level have on cells?:
Cells swell because of the influx of NaCl
2. Free radicals play a major role in the initiation and progression of
which disease?: Cardiovascular disease such as hypertension and ischemic
heart disease
3. The kind of genetic mutation that results in the change of an amino acid
sequence in the protein sequence is described as a: Missense mutation
4. An example of physiologic atrophy is: Thymus gland changes during
childhood
5. Which option best supports the reason more energy is produced when a
person is exercising: Muscle cells have more mitochondria to meet energy
demands
6. Which component form the structure of DNA: Nucleotides
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, 7. A patient is diagnosed with type one diabetes mellitus. At a cellular level,
which function is likely to be involved?: Is answers are right but inability of
ribosomes to produce a specific type of protein
8. Which factor is essential in order for protein synthesis to occur?: Specific
information from the nucleus of the cell
9. A client has a growth removed from the body. Which histologic finding
indicates that the growth is classified as benign?: Differentiation
10. Which chromosomal abnormalities have been linked with down
syndrome?: Translocation
11. Tumor necrosis factor alpha and interleukin one contribute to shark
states because they induce production of what?: Nitric oxide
12. During fertilization each parent contribute the DNA being passed onto
the offspring. Which genetic expression in the offspring is validation of
genetic contribution by a parent?: The sex of the offspring
13. The RB one gene is which kind of gene?: Tumor suppressor gene
14. Mutation and only one allele of the genes listed below which normally
promotes cell growth is associated which changes associated with
cancer: DNA repair genes
15. Screening test that measures the presence of blood in the stool indicate
FOBT and CEA: False
16. Sext linked disorders frequently are associated with the X chromosome
and are predominantly recessive: True
17. A tetratogenic agent is an environmental agent that produces
abnormalities only during the first four weeks of embryonic or fetal
development: True
18. Messenger RNA carries the instructions for protein synthesis: True
19. Which of the following respiratory structures would be found in the
respiratory zone?: Alveoli
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Questions and Answers – Complete Study Material
This document contains a complete set of midterm exam questions and answers for the MSN-FNP 570
Advanced Pathophysiology course. It includes key topics such as ischemia, genetic mutations,
respiratory disorders, cardiovascular physiology, neurological conditions, and immune responses. The
material provides accurate and concise answers, making it a useful resource for preparation and review.
1. During ischemia, what effect does the loss of ATP level have on cells?:
Cells swell because of the influx of NaCl
2. Free radicals play a major role in the initiation and progression of
which disease?: Cardiovascular disease such as hypertension and ischemic
heart disease
3. The kind of genetic mutation that results in the change of an amino acid
sequence in the protein sequence is described as a: Missense mutation
4. An example of physiologic atrophy is: Thymus gland changes during
childhood
5. Which option best supports the reason more energy is produced when a
person is exercising: Muscle cells have more mitochondria to meet energy
demands
6. Which component form the structure of DNA: Nucleotides
1/9
, 7. A patient is diagnosed with type one diabetes mellitus. At a cellular level,
which function is likely to be involved?: Is answers are right but inability of
ribosomes to produce a specific type of protein
8. Which factor is essential in order for protein synthesis to occur?: Specific
information from the nucleus of the cell
9. A client has a growth removed from the body. Which histologic finding
indicates that the growth is classified as benign?: Differentiation
10. Which chromosomal abnormalities have been linked with down
syndrome?: Translocation
11. Tumor necrosis factor alpha and interleukin one contribute to shark
states because they induce production of what?: Nitric oxide
12. During fertilization each parent contribute the DNA being passed onto
the offspring. Which genetic expression in the offspring is validation of
genetic contribution by a parent?: The sex of the offspring
13. The RB one gene is which kind of gene?: Tumor suppressor gene
14. Mutation and only one allele of the genes listed below which normally
promotes cell growth is associated which changes associated with
cancer: DNA repair genes
15. Screening test that measures the presence of blood in the stool indicate
FOBT and CEA: False
16. Sext linked disorders frequently are associated with the X chromosome
and are predominantly recessive: True
17. A tetratogenic agent is an environmental agent that produces
abnormalities only during the first four weeks of embryonic or fetal
development: True
18. Messenger RNA carries the instructions for protein synthesis: True
19. Which of the following respiratory structures would be found in the
respiratory zone?: Alveoli
2/9
