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CPC Medical Terminology – Essential Terms for AAPC Medical Coding Exam Prep 2024–2025 – Root Words, Prefixes, and Suffixes for Accurate Coding

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This document focuses on the core medical terminology needed for success on the AAPC CPC exam in 2024–2025. It includes definitions and usage of essential prefixes, suffixes, and root words commonly encountered in CPT, ICD-10-CM, and HCPCS coding. Organized by body system and function, this resource helps coders interpret medical documentation accurately and select the correct codes based on clinical language.

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Uploaded on
July 25, 2025
Number of pages
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Written in
2024/2025
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CPC Medical Terminology – Essential Terms for AAPC
Medical Coding Exam Prep 2024–2025
This document provides a focused collection of medical terminology essential for
success on the AAPC Certified Professional Coder (CPC) exam. It includes root
words, prefixes, suffixes, and abbreviations commonly used in coding scenarios,
organized by body system and function. Perfect for reinforcing vocabulary
knowledge and improving coding fluency for the 2024–2025 certification cycle.


1. Derm/o: Skin
2. Dermat/o: Skin
3. Hidr/o: sweat, perspiration
4. Kerat/o: keratin, horny layer of skin
5. Melan/o: dark, black, melanin
6. Onych/o: nail
7. Seb/o: sebum, sebaceous gland
8. Trich/o: hair
9. Arthr/o: joint
10. Burs/o: bursa, sac of fluid near joint
11. Chondr/o: cartilage
12. Erg/o: work
13. Fasci/o: fascia
14. Kin/o, kinesi/o: movement
15. Muscul/o: muscle
16. My/o: muscle
17. Myel/o: bone marrow, spinal cord
18. Oste/o: bone



, 19. Synov/i: synovial fluid, joint, or
membrane
20. Ten/o, tendin/o: tendon
21. Ton/o: tone; pressure
22. base of the word is considered the: the root
23. Bronch/o: bronchus 24. Laryng/o: larynx
25. Pharyng/o: pharynx
26. Phren/o: diaphragm
27. Phrenic/o: phrenic nerve
28. Pleur/o: pleura
29. Pneumon/o: lung
30. Pneum/o, pneumat/o: air, gas; respiration, lung
31. Pulm/o, pulmon/o: lungs
32. Rhin/o: nose
33. Spir/o: breathing
34. Trache/o: trachea
35. Erythr/o, erythrocyt/o: red blood cell
36. Hem/o, hemat/o: blood
37. Immun/o: immunity, immune system
38. Leuk/o, leukocyt/o: white blood cell
39. Lymph/o: lymph, lymphatic system
40. Lymphaden/o: lymph node
41. Lymphangi/o: lymphatic vessel
42. Splen/o: spleen
43. Thromb/o: blood clot
44. Thrombocyt/o: platelet, thrombocyte
45. Thym/o: thymus gland
46. Tonsil/o: tonsil
47. Angi/o: vessel
48. Aort/o: aorta
49. Arter/o, arteri/o: artery
50. Arteriol/o: arteriole
51. Atri/o: atrium

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