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Best Grades | Must Pass | Latest Update | Correct Answers Cardiovascular adaptations to pregnancy

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Best Grades | Must Pass | Latest Update | Correct Answers Cardiovascular adaptations to pregnancy BP-- Decreases slightly in 2nd trimester and then gradually returns in 3rd trimester May decrease in left lateral position Hematology adaptations in pregnancy Hct drop 28-40% Coagulability -- Hyper coagulable during pregnancy due to increased clotting factors and decrease fibrinolysis Best Grades | Must Pass | Latest Update | Correct Answers | 2024/ 2025 Renal changes in pregnancy GFR, renal plasma flow, Cr Cl increases Some normal glycosuria and proteinuria may occur Ureters, urethra, and bladder dilate Decreased bladder capacity and increase urine production Increase risk of UTI due to urinary stasis GI changes in pregnancy Lower esophageal sphincter tone can cause reflux Nausea and vomiting Constipation Metabolic adaptations in pregnancy Increased fat deposits Increased blood lipids Increase salt accumulation Increased water retention Increased body weight Respiratory adaptations in pregnancy Increased VO2 Best Grades | Must Pass | Latest Update | Correct Answers | 2024/ 2025 Impaired ventilation (rise in diaphragm) Musculoskeletal adaptations Increased joint laxity Increased risk of strains and sprains Gradual increase in lordosis Separation of rectus abdominis due to pressure from an enlarged uterus Integumentary changes in pregnancy Striae gravidum -- stretch marks Mask of chloasma -- irregular brown blotches and pigmentation on the cheeks or forehead Endocrine adaptations in pregnancy Increased HCG Increased human placental lactogen Increases estrogen Increased progesterone Emotional adaptations in pregnancy Best Grades | Must Pass | Latest Update | Correct Answers | 2024/ 2025 Increased emotional lability Increased instability

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Best Grades | Must Pass | Latest Update
| Correct Answers

Cardiovascular adaptations to pregnancy


BP--
Decreases slightly in 2nd trimester and then gradually returns in 3rd trimester May
decrease in left lateral position


Hematology adaptations in pregnancy

Hct drop 28-40%



Coagulability --
Hyper coagulable during pregnancy due to increased clotting factors and decrease
fibrinolysis


Best Grades | Must Pass | Latest Update | Correct Answers | 2024/ 2025



Renal changes in pregnancy

GFR, renal plasma flow, Cr Cl increases

Some normal glycosuria and proteinuria may occur Ureters, urethra, and bladder
dilate
Decreased bladder capacity and increase urine production Increase risk of UTI due
to urinary stasis


GI changes in pregnancy

Lower esophageal sphincter tone can cause reflux Nausea and vomiting
Constipation


Metabolic adaptations in pregnancy

,Increased fat deposits Increased blood lipids Increase salt accumulation Increased
water retention Increased body weight


Respiratory adaptations in pregnancy

Increased VO2

Best Grades | Must Pass | Latest Update | Correct Answers | 2024/ 2025

Impaired ventilation (rise in diaphragm)



Musculoskeletal adaptations

Increased joint laxity

Increased risk of strains and sprains Gradual increase in lordosis
Separation of rectus abdominis due to pressure from an enlarged uterus



Integumentary changes in pregnancy



Striae gravidum -- stretch marks


Mask of chloasma -- irregular brown blotches and pigmentation on the cheeks or
forehead



Endocrine adaptations in pregnancy

Increased HCG
Increased human placental lactogen Increases estrogen
Increased progesterone


Emotional adaptations in pregnancy


Best Grades | Must Pass | Latest Update | Correct Answers | 2024/ 2025

Increased emotional lability Increased instability

,Estrogen during pregnancy

Promotes growth of the uterus and glandular breast tissue Increase uterine blood
flow
Increased insulin like growth factors Stimulates growth of uterine muscle mass
Enhances myometrial contractility Increased sensitivity to oxytocin

Progesterone in pregnancy

Inhibits production of prostaglandins in uterus prevents myometrial contractions
Withdrawal of progestin at term leads to uterine contractions and onset of labor


Placenta

-Metabolizes and synthesizes agents necessary for sustaining pregnancy

-Provides immunologic barrier between maternal and fetal systems

-Functions as major endocrine gland


Hormones produced by placenta --


Best Grades | Must Pass | Latest Update | Correct Answers | 2024/ 2025

HCG (human chorionic gonadotropin) HPL (human placental lactogen) Estrogen
Progesterone



HCG sHuman schorionic sgonadotropin



Major srole sis ssustain sthe scorpus sluteum sand sits sproduction sof sprogesterone sand
sestrogen




Secreted sfor s8-10 sweeks sat swhich stime sthe splacenta sfunction sis sadequate sand
sbecomes sthe smajor sproducer sof sprogestin sand sestrogen




Levels snormally sdouble severy s48-72 shours sand sdoes suntil sit speaks

, Stabilizes sat s20,000


Nausea sand svomiting s-- snatural srise sand sfall sof sHCG slevels scorrespond sto
snausea sand svomiting sof spregnancy sduring sfirst strimester salthough sno sdirect

scause


Urine spregnancy stest s-- smay sbe spositive s2 sweeks safter sconception sor s5 sweeks
safter sLMP




HPL sHuman splacental slactogen




Best sGrades | sMust sPass | sLatest sUpdate | sCorrect sAnswers | s2024/ 2025

Increases smaternal sfatty sacids sand striglycerides



Increases smaternal sinsulin sresistance sto sreserve sglucose sfor sthe sfetus


Fetus sbegins sto sproduce sinsulin sjust sbefore sbirth



Relaxin



Prepares sthe sendometrium sdecidual stissue sto sensure smaintenance sof searly
spregnancy




Inhibits suterine sactivity sduring spregnancy sand stogether swith sprogesterone,
ssoftens sligaments sresulting sin sminor sinstability sof spelvis sto swiden sand sfacilitate

sbirth




Presumptive ssigns sof spregnancy

Amenorrhea snausea, svomiting sfatigue
urinary sfrequency sskin schanges schloasma
linea snegra sstriae

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