Hematology Board Exam Questions and answers New
2025/2026 NEW!!
What is the first type of cell produced by the developing embryo? - Correct Answers Erythrocyte
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Il` What percentage of tissue located in the bone marrow cavities of adults is fat? - Correct Answers
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50%
Il` Il` Il`
Il` Not characteristic of pluripotent hematopoietic stem cells? - Correct Answers Express the stem
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` cell marker CD13
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Il` In an adult, what are the two best areas for obtaining active bone marrow by aspiration? - Correct
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` Answers Posterior iliac crest and sternum Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` What is the normal ratio of myeloid to erythroid precursors in bone marrow? - Correct Answers
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` 4:1
Il` Does not accurately describe hematopoietic growth factors? - Correct Answers Action of
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Il` majority is lineage restricted Il` Il` Il`
Il` In the third month of gestation, what is the primary site of hematopoiesis? - Correct Answers
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` Liver
Il` The mechanism that relays information about tissue oxygen levels to EPO producing sites is
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` located: - Correct Answers In the kidney Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` Antigen-independent lymphopoiesis occurs in primary lymphoid tissue located in the: - Correct Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` Answers Thymus and bone marrow Il` Il` Il` Il` Il` Il` Il` Il`
,Il` In what area of the bone marrow, does hematopoiesis take place? - Correct Answers Cords
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` Bone marrow cellularity refers to the ratio of: - Correct Answers Hematopoietic tissue to
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` adipose tissue Il`
Il` Interleukins and colony simulating factors are cytokines produced by: - Correct Answers
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` Monocytes and T lymphocytes Il` Il` Il`
Il` What is the approximate total blood volume in an adult? - Correct Answers 6 L
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` The myeloid progenitor cell can produce cells committed to: - Correct Answers Granulocytic,
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` erythrocytic, monocytic or megakaryocytic lineage Il` Il` Il` Il`
Il` The largest hematopoietic cells in normal bone marrow: - Correct Answers Megakaryocytes
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` When evaluating a bone marrow aspirate smear, which finding is considered abnormal? - Correct
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` Answers The presence of 10% myeloblasts on the cell differential count
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` As most blood lines mature what is characteristic? - Correct Answers Nucleus to cytoplasm ratio
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` decreases
Il` Describes TPO: - Correct Answers Hormone produced by the liver that stimulates
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` megakaryopoiesis
Il` When the hepatic phase of fetal life is reactivated in an adult, hematopoiesis can be termed: -
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` Correct Answers Myeloid metaplasia or extramedullary
Il` Il` Il` Il` Il` Il` Il` Il` Il`
,Il` What is the average life span of a normal red blood cell? - Correct Answers 120 days
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` The function of Na+K+ cation pump is to maintain a high level of: - Correct Answers Intracellular
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Il` K+
Il` Depicts the structure of the hemoglobin molecule: - Correct Answers Four heme groups, four
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` globin chains Il`
Il` Describes the process known as culling: - Correct Answers Removal of abnormal red cells by the
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` spleen
Il` Hemoglobin forms that are incapable of oxygen transport include: - Correct Answers
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` Carboxyhemoglobin and methemoglobin Il` Il`
Il` The majority of iron found in an adult is a constituent of: - Correct Answers Hemoglobin
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` A senescent red blood cell is one that has been: - Correct Answers Lived its life span
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Il` What red cell morphologic abnormality is described by the term "poikilocytosis"? - Correct
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Il` Answers Deviations from normal shape Il` Il` Il` Il` Il` Il` Il` Il`
Il` HJ bodies are composed of: - Correct Answers DNA
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` When spherocytes are reported, what is observed on the peripheral blood smear? - Correct
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` Answers Red cells without a central pallor Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` The red cells found in lead poisoning characteristically exhibit coarse granules composed of - that
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` are reported as -. - Correct Answers Aggregated ribosomes; basophilic stippling
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
, Il` Rouleaux of red blood cells when seen in the monolayer of a blood smear is characteristic of: -
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` Correct Answers Multiple myeloma Il` Il` Il` Il` Il` Il` Il`
Il` Most frequently associated with HJ bodies: - Correct Answers Post-splenectomy
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` True about iron absorption: - Correct Answers Absorption increases when erythropoietic
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` activity increases Il`
Il` What term describes a red blood cell that contains iron granules or deposit? - Correct Answers
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` Siderocyte
Il` Associated with a "shift to the left" in the oxygen dissociation curve of hemoglobin? - Correct
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` Answers Decreased oxygen release Il` Il` Il` Il` Il` Il` Il`
Il` Does not characterize EPO: - Correct Answers Decreases stimulation of erythropoiesis when
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` cellular hypoxia increases Il` Il`
Il` Factor will result in an immediate increase in oxygen delivery to the tissues? - Correct Answers
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` Increased hemoglobin binding of 2,3-BPG Il` Il` Il` Il`
Il` Periods of intense erythropoietin activity cause premature release of marrow reticulocytes into
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` the blood. True of early reticulocytes: - Correct Answers Loss of residual RNA occurs
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` immediately upon marrow release Il` Il` Il`
Il` Which inclusion is only visible with supravital staining? - Correct Answers Heinz bodies
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` The presence of schistocytes on the peripheral blood smear is commonly associated with: -
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` Correct Answers Increased red cell destruction
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2025/2026 NEW!!
What is the first type of cell produced by the developing embryo? - Correct Answers Erythrocyte
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` What percentage of tissue located in the bone marrow cavities of adults is fat? - Correct Answers
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
50%
Il` Il` Il`
Il` Not characteristic of pluripotent hematopoietic stem cells? - Correct Answers Express the stem
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` cell marker CD13
Il` Il`
Il` In an adult, what are the two best areas for obtaining active bone marrow by aspiration? - Correct
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` Answers Posterior iliac crest and sternum Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` What is the normal ratio of myeloid to erythroid precursors in bone marrow? - Correct Answers
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` 4:1
Il` Does not accurately describe hematopoietic growth factors? - Correct Answers Action of
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` majority is lineage restricted Il` Il` Il`
Il` In the third month of gestation, what is the primary site of hematopoiesis? - Correct Answers
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` Liver
Il` The mechanism that relays information about tissue oxygen levels to EPO producing sites is
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` located: - Correct Answers In the kidney Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` Antigen-independent lymphopoiesis occurs in primary lymphoid tissue located in the: - Correct Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` Answers Thymus and bone marrow Il` Il` Il` Il` Il` Il` Il` Il`
,Il` In what area of the bone marrow, does hematopoiesis take place? - Correct Answers Cords
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` Bone marrow cellularity refers to the ratio of: - Correct Answers Hematopoietic tissue to
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` adipose tissue Il`
Il` Interleukins and colony simulating factors are cytokines produced by: - Correct Answers
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` Monocytes and T lymphocytes Il` Il` Il`
Il` What is the approximate total blood volume in an adult? - Correct Answers 6 L
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` The myeloid progenitor cell can produce cells committed to: - Correct Answers Granulocytic,
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` erythrocytic, monocytic or megakaryocytic lineage Il` Il` Il` Il`
Il` The largest hematopoietic cells in normal bone marrow: - Correct Answers Megakaryocytes
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` When evaluating a bone marrow aspirate smear, which finding is considered abnormal? - Correct
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` Answers The presence of 10% myeloblasts on the cell differential count
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` As most blood lines mature what is characteristic? - Correct Answers Nucleus to cytoplasm ratio
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` decreases
Il` Describes TPO: - Correct Answers Hormone produced by the liver that stimulates
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` megakaryopoiesis
Il` When the hepatic phase of fetal life is reactivated in an adult, hematopoiesis can be termed: -
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` Correct Answers Myeloid metaplasia or extramedullary
Il` Il` Il` Il` Il` Il` Il` Il` Il`
,Il` What is the average life span of a normal red blood cell? - Correct Answers 120 days
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` The function of Na+K+ cation pump is to maintain a high level of: - Correct Answers Intracellular
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` K+
Il` Depicts the structure of the hemoglobin molecule: - Correct Answers Four heme groups, four
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` globin chains Il`
Il` Describes the process known as culling: - Correct Answers Removal of abnormal red cells by the
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` spleen
Il` Hemoglobin forms that are incapable of oxygen transport include: - Correct Answers
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` Carboxyhemoglobin and methemoglobin Il` Il`
Il` The majority of iron found in an adult is a constituent of: - Correct Answers Hemoglobin
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` A senescent red blood cell is one that has been: - Correct Answers Lived its life span
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` What red cell morphologic abnormality is described by the term "poikilocytosis"? - Correct
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` Answers Deviations from normal shape Il` Il` Il` Il` Il` Il` Il` Il`
Il` HJ bodies are composed of: - Correct Answers DNA
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` When spherocytes are reported, what is observed on the peripheral blood smear? - Correct
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` Answers Red cells without a central pallor Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` The red cells found in lead poisoning characteristically exhibit coarse granules composed of - that
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` are reported as -. - Correct Answers Aggregated ribosomes; basophilic stippling
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
, Il` Rouleaux of red blood cells when seen in the monolayer of a blood smear is characteristic of: -
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` Correct Answers Multiple myeloma Il` Il` Il` Il` Il` Il` Il`
Il` Most frequently associated with HJ bodies: - Correct Answers Post-splenectomy
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` True about iron absorption: - Correct Answers Absorption increases when erythropoietic
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` activity increases Il`
Il` What term describes a red blood cell that contains iron granules or deposit? - Correct Answers
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` Siderocyte
Il` Associated with a "shift to the left" in the oxygen dissociation curve of hemoglobin? - Correct
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` Answers Decreased oxygen release Il` Il` Il` Il` Il` Il` Il`
Il` Does not characterize EPO: - Correct Answers Decreases stimulation of erythropoiesis when
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` cellular hypoxia increases Il` Il`
Il` Factor will result in an immediate increase in oxygen delivery to the tissues? - Correct Answers
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` Increased hemoglobin binding of 2,3-BPG Il` Il` Il` Il`
Il` Periods of intense erythropoietin activity cause premature release of marrow reticulocytes into
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` the blood. True of early reticulocytes: - Correct Answers Loss of residual RNA occurs
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` immediately upon marrow release Il` Il` Il`
Il` Which inclusion is only visible with supravital staining? - Correct Answers Heinz bodies
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` The presence of schistocytes on the peripheral blood smear is commonly associated with: -
Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il` Il`
Il` Correct Answers Increased red cell destruction
Il` Il` Il` Il` Il` Il` Il` Il` Il`
