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Term
Reduce inflammation, improve barrier function
, Often involves post-translational modifications (PTMs):
E.g., phosphorylation
• Kinase transfers phosphate from ATP to protein
• Phosphatase removes phosphate from protein
• Changes protein conformation
-Impacts enzymatic activity, protein-protein interactions, etc.
• Prevent antibiotic from reaching ribosome (Efflux, decreased permeability)
• Target modification (Change ribosome structure so antibiotic cannot bind)
• Target protection (Produce a protein that removes antibiotic from ribosome)
• Antibiotic modification/degradation
• Synthesized large DNA fragments
• Used yeast cells to carry out homologous recombination
• Assembled DNA fragments into larger and larger pieces
• Combined to make 1 Mb chromosome
• Shows that organisms can be manufactured
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Term
Where does V. cholerae shed?
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in feces
-structure, function
• May contaminate drinking
-eukaryotes more than prokaryotes
water, repeating cycle
, In bacteria Bacteria - after genes
• Each mRNA can be translated by -tells RNA polymerase where to
multiple ribosomes stop
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Term
What is pseudomonas aeruginosa?
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• Major threat if immune defences compromised
• Causes severe inflammation, damaging host tissue
• Often considered to be opportunistic
• Chronic infections can lead to genetic diversity
proteins that limit the ability of RNA polymerase to transcribe a gene
• Often prevent polymerase from binding to promoter
• Decrease gene transcription
1. attachment, entry (endocytosis)
2. uncoating, release from endosome
3. transcription
4. translation (+RNA), replication (+RNA makes -RNA)
5. assembly
6. exocytosis/lysis?
Microbes can be used to control pollution
• Naturally occurring, or deliberately introduced
, • E.g., bacteria that break down oil can manage oil spills
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Term
What did other researchers discover after Griffith's experiment?
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transformation was caused by lipid transformation occurred through
Exchange viral infection
transformation resulted from transformation resulted from
transfer of Proteins transfer of DNA
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Term
What is haemolysin?
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food ingredient that stimulates growth/activity of certain gut