pharmacodynamics
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study of the effect that drugs have on the body
Controlled substance Schedule III/IIIN
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lower abuse level than II with acceptable therapeutic use
ex.combo products containing less than 15mg of hydrocodone (Vicodin),
products not more than 90 mg codeine (codeine w/Tylenol),
buprenorphine (suboxone)
IIN non-narcs: benzphetamine, phendimetrazine, ketamine, and anabolic
steroids (Depo-Testosterone, Androgel)
Distribution
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transport of drugs to receptor site, storage site, and elimination site
pharmacokinetics
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study of the effect the body has on a drug
selectivity
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, greater affinity for certain receptors
"the ligand is picky"
ex: selective- atenolol
non-selective-propanolol
Adverse drug event -predictable
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dependent on dose,
r/t age/gender/patient hx
Antagonist
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ligand that bonds to receptor and does not activate receptor
Agonist
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ligand that binds and activates receptor
Adverse drug event- unpredictable
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study of the effect that drugs have on the body
Controlled substance Schedule III/IIIN
,Give this one a try later!
lower abuse level than II with acceptable therapeutic use
ex.combo products containing less than 15mg of hydrocodone (Vicodin),
products not more than 90 mg codeine (codeine w/Tylenol),
buprenorphine (suboxone)
IIN non-narcs: benzphetamine, phendimetrazine, ketamine, and anabolic
steroids (Depo-Testosterone, Androgel)
Distribution
Give this one a try later!
transport of drugs to receptor site, storage site, and elimination site
pharmacokinetics
Give this one a try later!
study of the effect the body has on a drug
selectivity
Give this one a try later!
, greater affinity for certain receptors
"the ligand is picky"
ex: selective- atenolol
non-selective-propanolol
Adverse drug event -predictable
Give this one a try later!
dependent on dose,
r/t age/gender/patient hx
Antagonist
Give this one a try later!
ligand that bonds to receptor and does not activate receptor
Agonist
Give this one a try later!
ligand that binds and activates receptor
Adverse drug event- unpredictable
