AAMC uworld review Questions and Answers (Expert Solutions)

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AAMC uworld review Questions and
Answers (Expert Solutions)

Q: 3 models of DNA replication

ANS 🗹🗹: semiconservative, conservative, dispersive


Q: wobble base pairing

ANS 🗹🗹: Only occurs at third codon position between tRNA and mRNA.


Q: Translation directionality for mRNA transcript

ANS 🗹🗹: 5' to 3' : mRNA codon

3' to 5' : tRNA anticodon

N terminus to C terminus: amino acid sequence


Q: generation of cDNA library

ANS 🗹🗹: mRNA--> single stranded DNA--> double stranded DNA(opposite
directionality to mRNA)


Q: alternative splicing

ANS 🗹🗹: multiple different proteins from the same molecule of mRNA


Q: conjugation

ANS 🗹🗹: exchange of genetic information between prokaryotes in form of plasmic
DNA


Q: transformation

ANS 🗹🗹: occurs when prokaryotes pick up foreign genetic information from
surroundings


Q: redundant but not ambigious

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ANS 🗹🗹: more than one codon codes for an amino acid, but every codon codes for
just one amino acid


Q: approximate weight of amino acid

ANS 🗹🗹: 110 kDA


Q: base pairing

ANS 🗹🗹: A-T/U

G-C


Q: percentages of mRNA

ANS 🗹🗹: 1.5%


Q: percentage of rRNA

ANS 🗹🗹: 80%


Q: percentage of tRNA

ANS 🗹🗹: 15%


Q: eukaryotes have .... ORI

ANS 🗹🗹: multiple


Q: prokaryotes have.... ORI

ANS 🗹🗹: single


Q: attachment of nucleotides during DNA replication

ANS 🗹🗹: occurs at the free 3' OH group


Q: Telomeres function

ANS 🗹🗹: noncoding DNA sequence protects rest of chromosome from degradation.
NOT ENCODED PROTEINS(this would be dangerous), highly repetitive sequences


Q: frameshift mutation