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This document contains the full test bank for Huether and McCance’s Understanding Pathophysiology, 2nd Canadian Edition, authored by Kelly Power, Stephanie Zettel, and Mohamed Toufic El Hussein. It includes hundreds of multiple-choice and multiple-response questions with detailed answers and rationales, covering all textbook units and chapters. Topics include cellular biology, genetic diseases, immunology, cancer biology, neurological and endocrine systems, cardiovascular and respiratory functions, and pediatric and adult pathophysiology. The questions align with nursing curricula and Canadian healthcare standards, ideal for exam prep and instructional use. PART ONE: BASIC CONCEPTS OF PATHOPHYSIOLOGY Unit 1: The Cell 1. Cellular Biology 2. Genes and Genetic Diseases 3. Epigenetics and Disease 4. Altered Cellular and Tissue Biology 5. Fluids and Electrolytes, Acids and Bases Unit 2: Mechanisms of Self-Defense 6. Innate Immunity: Inflammation and Wound Healing 7. Adaptive Immunity 8. Infection and Defects in Mechanisms of Defense 9. Stress and Disease Unit 3: Cellular Proliferation: Cancer 10. Biology of Cancer 11. Cancer Epidemiology 12. Cancer in Children and Adolescents PART TWO: BODY SYSTEMS AND DISEASES Unit 4: The Neurologic System 13. Structure and Function of the Neurologic System 14. Pain, Temperature, Sleep, and Sensory Function 15. Alterations in Cognitive Systems, Cerebral Hemodynamics and Motor Function 16. Disorders of the Central and Peripheral Nervous Systems and Neuromuscular Junction 17. Alterations of Neurologic Function in Children Unit 5: The Endocrine System 18. Mechanisms of Hormonal Regulation 19. Alterations of Hormonal Regulation Unit 6: The Hematologic System 20. Structure and Function of the Hematologic System 21. Alterations in Hematologic Function 22. Alterations of Hematologic Function in Children Unit 7: The Cardiovascular and Lymphatic Systems 23. Structure and Function of the Cardiovascular and Lymphatic Systems 24. Alterations of Cardiovascular Function 25. Alterations of Cardiovascular Function in Children Unit 8: The Pulmonary System 26. Structure and Function of the Pulmonary System 27. Alterations of Pulmonary Function 28. Alterations of Pulmonary Function in Children Unit 9: The Renal and Urologic Systems 29. Structure and Function of the Renal and Urologic Systems 30. Alterations of Renal and Urinary Tract Function 31. Alterations of Renal and Urinary Tract Function in Children Unit 10: The Reproductive Systems 32. Structure and Function of the Reproductive Systems 33. Alterations of the Female Reproductive System 34. Alterations of the Male Reproductive System Unit 11: The Digestive System 35. Structure and Function of the Digestive System 36. Alterations of Digestive Function 37. Alterations in Digestive Function in Children Unit 12: The Musculoskeletal and Integumentary Systems 38. Structure and Function of the Musculoskeletal System 39. Alterations of Musculoskeletal Function 40. Alterations of Musculoskeletal Function in Children 41. Structure, Function, and Disorders of the Integument 42. Alterations of the Integument in Children
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