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AcquisitionsIEditor:ISusanIM.IHartman
Editor-in-Chief:IColletteIBishopIHendler,IRN,IMS,IMA,ICIC
ClinicalIProjectIManager:IJanetIRader,IRN,IBSN
ClinicalIEditors:IJohnIBodnar,IRN,IBSN,IBS;IJoannaIE.ICain,IRN,IBSN,IBA;IKerrinIDoranIKunze,IRN,IDNP,IAPRN,IFNP-
BC;IMeghanILynch,IRN,IBSN;ILisaIMerenda,IMSN,IRN,ICRRN;ILindaILeeIPhelps,IRN,IDNP
ManagingIEditors:ICarlaIA.IRudoyIVitale,IPhD;I DianeILabus;IEllenISellers
Editors:IKarenIC.IComerford,IMaryIT.IDurkin
EditorialIAssistant:ILindaIK.IRuhf
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Designer:IJosephIJohnIClark
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onIServices:IAptara,IInc.
©I2023IbyIWoltersIKluwer.IAllIrightsIreserved.IThisIbookIisIprotectedIbyIcopyright.INoIpartIofIthisIbookImayIbeIreproduced
IorItransmittedIinIanyIformIorIbyIanyImeans,IincludingIasIphotocopiesIorIscanned-
inIorIotherIelectronicIcopies,IorIutilizedIbyIanyIinformationIstorageIandIretrievalIsystemIwithoutIwrittenIpermissionIfromIth
eIcopyrightIowner,IexceptIforIbriefIquotationsIembodiedIinIcriticalIarticlesIandIreviews.IMaterialsIappearingIinIthisIbookIpr
eparedIbyIindividualsIasIpartIofItheirIofficialIdutiesIasIU.S.IgovernmentIemployeesIareInotIcoveredIbyItheIabove-
mentionedIcopyright.IToIrequestIpermission,IpleaseIcontactIWoltersIKluwerIatITwoICommerceISquare,I2001IMarketIStr
eet,IPhiladelphia,IPAI19103,,IorIviaIwebsiteIatIshop.lww.comI(productsIandIservices).
9I8I7I6I5I4I3I2I1
PrintedIinIChina
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010522IISSN:I027
3-320X
ISBN-13:I 978-1-9751-8338-7
ISBN-10:I 1-9751-8336-3
ThisIworkIisIprovidedI“asIis,”IandItheIpublisherIdisclaimsIanyIandIallIwarranties,IexpressIorIimplied,IincludingIanyIwarrantiesIasI
toIaccuracy,Icomprehensiveness,IorIcurrencyIofItheIcontentIofIthisIwork.
ThisIworkIisInoIsubstituteIforIindividualIpatientIassessmentIbasedIuponIhealthIcareIprofessionals’IexaminationIofIeachIpa
tientIandIconsiderationIof,IamongIotherIthings,Iage,Iweight,Igender,IcurrentIorIpriorImedicalIconditions,ImedicationIhistor
y,IlaboratoryIdata,IandIotherIfactorsIuniqueItoItheIpatient.ITheIpublisherIdoesInotIprovideImedicalIadviceIorIguidance,IandI
thisIworkIisImerelyIaIreferenceItool.IHealthIcareIprofessionals,IandInotItheIpublisher,IareIsolelyIresponsibleIforItheIuseIofIt
hisIwork,IincludingIallImedicalIjudgmentsIandIforIanyIresultingIdiagnosisIandItreatments.
GivenIcontinuous,IrapidIadvancesIinImedicalIscienceIandIhealthIinformation,IindependentIprofessionalIverificationIofIme
dicalIdiagnoses,Iindications,IappropriateIpharmaceuticalIselectionsIandIdosages,IandItreatmentIoptionsIshouldIbeImadeI
andIhealthIcareIprofessionalsIshouldIconsultIaIvarietyIofIsources.IWhenIprescribingImedication,IhealthIcareIprofessional
sIareIadvisedItoIconsultItheIproductIinformationIsheetI(theImanufacturer’sIpackageIinsert)IaccompanyingIeachIdrugItoIver
ify,IamongIotherIthings,IconditionsIofIuse,Iwarnings,IandIsideIeffectsIandIidentifyIanyIchangesIinIdosageIscheduleIorIcont
raindications,IparticularlyIifItheImedicationItoIbeIadministeredIisInew,IinfrequentlyIused,IorIhasIaInarrowItherapeuticIrang
e.IToItheImaximumIextentIpermittedIunderIapplicableIlaw,InoIresponsibilityIisIassumedIbyItheIpublisherIforIanyIinjuryIand/
orIdamageItoIpersonsIorIproperty,IasIaImatterIofIproductsIliability,InegligenceIlawIorIotherwise,IorIfromIanyIreferenceItoIor
IuseIbyIanyIpersonIofIthisIwork.
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, ChiefINurse:IAnneIDabrowIWoods,IDNP,IRN,ICRNP,IANP-BC,IAGACNP-BC,I FAAN
AcquisitionsIEditor:ISusanIM.IHartman
Editor-in-Chief:IColletteIBishopIHendler,IRN,IMS,IMA,ICIC
ClinicalIProjectIManager:IJanetIRader,IRN,IBSN
ClinicalIEditors:IJohnIBodnar,IRN,IBSN,IBS;IJoannaIE.ICain,IRN,IBSN,IBA;IKerrinIDoranIKunze,IRN,IDNP,IAPRN,IFNP-
BC;IMeghanILynch,IRN,IBSN;ILisaIMerenda,IMSN,IRN,ICRRN;ILindaILeeIPhelps,IRN,IDNP
ManagingIEditors:ICarlaIA.IRudoyIVitale,IPhD;I DianeILabus;IEllenISellers
Editors:IKarenIC.IComerford,IMaryIT.IDurkin
EditorialIAssistant:ILindaIK.IRuhf
GraphicIArtsI&IDesignIManager:IStephenIDruding
Designer:IJosephIJohnIClark
SeniorIProductionIAssociate:IJustinIWrightIM
anufacturingIManager:IBethIWelshIProducti
onIServices:IAptara,IInc.
©I2023IbyIWoltersIKluwer.IAllIrightsIreserved.IThisIbookIisIprotectedIbyIcopyright.INoIpartIofIthisIbookImayIbeIreproduced
IorItransmittedIinIanyIformIorIbyIanyImeans,IincludingIasIphotocopiesIorIscanned-
inIorIotherIelectronicIcopies,IorIutilizedIbyIanyIinformationIstorageIandIretrievalIsystemIwithoutIwrittenIpermissionIfromIth
eIcopyrightIowner,IexceptIforIbriefIquotationsIembodiedIinIcriticalIarticlesIandIreviews.IMaterialsIappearingIinIthisIbookIpr
eparedIbyIindividualsIasIpartIofItheirIofficialIdutiesIasIU.S.IgovernmentIemployeesIareInotIcoveredIbyItheIabove-
mentionedIcopyright.IToIrequestIpermission,IpleaseIcontactIWoltersIKluwerIatITwoICommerceISquare,I2001IMarketIStr
eet,IPhiladelphia,IPAI19103,,IorIviaIwebsiteIatIshop.lww.comI(productsIandIservices).
9I8I7I6I5I4I3I2I1
PrintedIinIChina
NDH43-
010522IISSN:I027
3-320X
ISBN-13:I 978-1-9751-8338-7
ISBN-10:I 1-9751-8336-3
ThisIworkIisIprovidedI“asIis,”IandItheIpublisherIdisclaimsIanyIandIallIwarranties,IexpressIorIimplied,IincludingIanyIwarrantiesIasI
toIaccuracy,Icomprehensiveness,IorIcurrencyIofItheIcontentIofIthisIwork.
ThisIworkIisInoIsubstituteIforIindividualIpatientIassessmentIbasedIuponIhealthIcareIprofessionals’IexaminationIofIeachIpa
tientIandIconsiderationIof,IamongIotherIthings,Iage,Iweight,Igender,IcurrentIorIpriorImedicalIconditions,ImedicationIhistor
y,IlaboratoryIdata,IandIotherIfactorsIuniqueItoItheIpatient.ITheIpublisherIdoesInotIprovideImedicalIadviceIorIguidance,IandI
thisIworkIisImerelyIaIreferenceItool.IHealthIcareIprofessionals,IandInotItheIpublisher,IareIsolelyIresponsibleIforItheIuseIofIt
hisIwork,IincludingIallImedicalIjudgmentsIandIforIanyIresultingIdiagnosisIandItreatments.
GivenIcontinuous,IrapidIadvancesIinImedicalIscienceIandIhealthIinformation,IindependentIprofessionalIverificationIofIme
dicalIdiagnoses,Iindications,IappropriateIpharmaceuticalIselectionsIandIdosages,IandItreatmentIoptionsIshouldIbeImadeI
andIhealthIcareIprofessionalsIshouldIconsultIaIvarietyIofIsources.IWhenIprescribingImedication,IhealthIcareIprofessional
sIareIadvisedItoIconsultItheIproductIinformationIsheetI(theImanufacturer’sIpackageIinsert)IaccompanyingIeachIdrugItoIver
ify,IamongIotherIthings,IconditionsIofIuse,Iwarnings,IandIsideIeffectsIandIidentifyIanyIchangesIinIdosageIscheduleIorIcont
raindications,IparticularlyIifItheImedicationItoIbeIadministeredIisInew,IinfrequentlyIused,IorIhasIaInarrowItherapeuticIrang
e.IToItheImaximumIextentIpermittedIunderIapplicableIlaw,InoIresponsibilityIisIassumedIbyItheIpublisherIforIanyIinjuryIand/
orIdamageItoIpersonsIorIproperty,IasIaImatterIofIproductsIliability,InegligenceIlawIorIotherwise,IorIfromIanyIreferenceItoIor
IuseIbyIanyIpersonIofIthisIwork.
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