NPB 110A Midterm 2 Lecture, Quiz,
and Practice Midterm multiple choice
questions well answered to pass
What best describes the activity of mitogens? - correct answer ✔✔They induce cells to leave G1
Which phase of the cell cycle can last weeks or even years? - correct answer ✔✔G1 ?
What are the calcium levels in the cytoplasm of a typical mammalian cell? - correct answer
✔✔10-4 mM
Which of the following is incorrect with respect to the kinase Calcium-Calmodulin dependent
protein kinase II? - correct answer ✔✔After autophosphorylation when calcium levels fall, the
loss of calmodulin results in the kinase becoming inactive
What kind of mutation in Rb would allow cells to divide more frequently? - correct answer
✔✔A. Lower affinity for E2F
B. Deletion of Rb altogether
What would happen in mutant cells that cannot Phosphorylate Rb? - correct answer ✔✔Rb
can't unbind from E2F, E2F can't act on its CDK and drive the cell cycle forward
What are the differences between G0 and senescence? - correct answer ✔✔-Senescence is final
- the cell will never divide
-G0 is reversible - the cell can receive signals to go through G1
and Practice Midterm multiple choice
questions well answered to pass
What best describes the activity of mitogens? - correct answer ✔✔They induce cells to leave G1
Which phase of the cell cycle can last weeks or even years? - correct answer ✔✔G1 ?
What are the calcium levels in the cytoplasm of a typical mammalian cell? - correct answer
✔✔10-4 mM
Which of the following is incorrect with respect to the kinase Calcium-Calmodulin dependent
protein kinase II? - correct answer ✔✔After autophosphorylation when calcium levels fall, the
loss of calmodulin results in the kinase becoming inactive
What kind of mutation in Rb would allow cells to divide more frequently? - correct answer
✔✔A. Lower affinity for E2F
B. Deletion of Rb altogether
What would happen in mutant cells that cannot Phosphorylate Rb? - correct answer ✔✔Rb
can't unbind from E2F, E2F can't act on its CDK and drive the cell cycle forward
What are the differences between G0 and senescence? - correct answer ✔✔-Senescence is final
- the cell will never divide
-G0 is reversible - the cell can receive signals to go through G1
