FALL.COMPLETE EXAM 1,2 AND 3 QUESTIONS AND
ANSWERS. LATEST UPDATE.
Proteins that are fully translated in the cytosol and have a sorting signal 'Pro-Pro- Lys-Lys-
Lys-Arg-Lys-Val-' will end up in .
CORRECT ANS>>the interior of the nucleus
Someone has discovered a new drug that blocks the ability of Ran to exchange GDP for
GTP. What is the most likely effect of this drug on nuclear transport?
CORRECT ANS>>Nuclear transport receptors would be unable to release their cargo in the
nucleus
Using genetic engineering techniques, you have created a set of proteins that contain two
(and only two) conflicting signal sequences that specify different compartments; Signals for
import into the nucleus and import into the ER. The protein will end up in .
CORRECT ANS>>the ER
What do cyanide, azide, and carbon monoxide all have in common?
CORRECT ANS>>They all inhibit the final step of electron transport
What is the most logical sequence of steps for protein-protein interactions mediate fusion of
transport vesicles with appropriate membranes:
I. Rab proteins on the surface of each type of vesicle are recognized by corresponding
tethering proteins on the cytosolic surface of the target membrane.
II. The tethering protein has captured a vesicle y grabbing hold of its Rab protein
III. The SNAREs catalyzes the membrane fusion
IV. v-SNARE interact with complementary SNAREs on the target (t-SNARE) membrane
V. Deliver the soluble contents
CORRECT ANS>>I, II, IV, III, V
You have been given a cell line that does not form mature vesicles. This cell line forms
coated pits but vesicle budding and the removal of coat proteins don't happen. Which of the
following proteins might be lacking in this cell line?
CORRECT ANS>>dynamin Answer- d
Which of the following statements about vesicle budding from the Golgi is true?
CORRECT ANS>>Once vesicle budding occurs, clathrin molecules are released from the
vesicle
Akt promotes the survival of many cells by affecting the activity of Bad and Bcl2. Which of the
following statements is false?
CORRECT ANS>>In the presence of survival signal, Bad is phosphorylated Answer- d
, NADH contains a high-energy bond that, when cleaved, donates a pair of electrons to the
electron-transport chain. What are the immediate products of this bond cleavage?
CORRECT ANS>>(NAD+) + (H-)
The length of time a G protein will signal is determined by .
CORRECT ANS>>the GTPase activity of Gα
How does the structure of chloroplasts differ to that of mitochondria?
CORRECT ANS>>Only chloroplasts have a third membrane, the thylakoid membrane
Answer- d
In stage I of photosynthesis, a proton gradient is generated and ATP is synthesized. Where
do protons become concentrated in the chloroplast?
CORRECT ANS>>thylakoid space
Which of the following stages in the breakdown of the piece of toast you had for breakfast
generates the most ATP?
CORRECT ANS>>oxidative phosphorylation
Where are the proteins in the chloroplast synthesized?
CORRECT ANS>>in both the cytosol and the chloroplast Answer- d
Which of the following statements is not true?
CORRECT ANS>>The dark reactions produce ATP
You are interested in Kim, a soluble protein that functions within the ER lumen Given that
information, which of the following statements must be true?
CORRECT ANS>>Once the signal sequence from Kim has been cleaved, the signal peptide
will be ejected into the ER membrane and degraded Answer- d
Which of the following statements concerning the light reaction of photosynthesis is false?
CORRECT ANS>>Carbon dioxide fixation takes place
Receptor tyrosine kinases (RTKs)
CORRECT ANS>>are activated by ligand-induced dimerization
The following reactions are all common parts of some hormone processes:
I. Binding of the hormone to a receptor
II. Synthesis of cyclic AMP
III. Phosphorylation of the target enzyme
IV. Release of G-protein from the interior cell membrane
V. Activation of a protein kinase
I, II, IV, III, V
I, IV, II, V, III
I, IV, II, III, V
II, I, IV, V, III Answer- b