ACTUAL ANSWERS.
Indications ANSWER : -reasons forusing drugs
Contraindications ANSWER : -reasons for NOT using drugs
Pharmacokinetics ANSWER : -what happens to drugs when they enter the body
- Study of absorption, distribution, biotransformation, and excretion of drugs
VCPR ANSWER : -Veterinarian Client Patient relationship
Pharmacodynamics ANSWER : -how drugs exert their effects
Inactive ingredients ANSWER : -binders, coatings, coloring agents, disintegrants, fillers, etc
Regimen ANSWER : -plan for administration of the drug (route, frequency, duration, qty filled)
Prescription drug ANSWER : -when a drug has potential toxic effects or must be administered by trained
personnel
Extralabel use ANSWER : -use of a drug in a way not specified by the label
OTC drugs ANSWER : -may be purchased without a prescription
Controlled substances ANSWER : -drugs with potential for abuse or dependence
Bioavailability ANSWER : -the degree to which a drug is absorbed and reaches general circulation
, 3 main routes of drug administration ANSWER : -o Oral
o Topical
o Parenteral
There is also inhalations
Steady state ANSWER : -(Drug accumulation=drug elimination).
- Sometimes a loading dose is needed to help achieve this.
Plasma binding ANSWER : -Decreases drug availability (becomes inactive when bound)
4 different chemical reactions that occur in biotransformation ANSWER : -Oxidation, reduction,
hydrolysis and conjugation
Phase I biotransformation ANSWER : -Oxidation, reduction, hydrolysis
Phase II biotransformation ANSWER : -conjugation
Biotransformation in cats ANSWER : -Cats—reduced ability to form glucuronic acid (glucuronic acid is
used in Conjugation to make the drug more water soluble)
What are the routes for drug excretion? ANSWER : -Mostly via the kidneys after metabolism by the liver
o Other routes for excretion include the liver (bile), mammary glands, sweat glands, lungs, intestinal
tract, salivary glands, and skin
Which is the main organ for drug excretion? ANSWER : -Kidneys