Grand Canyon University NUR 631 – Final Exam Material – Advanced
Nursing Practice Comprehensive Questions
why does cancer come back - correct answer small areas of metastases can lie dormant only to
explode in growth later
Complete remission of leukemia is when less then 5% blasts in marrow and normal CBC values
malignant neoplasm of epithelial origin are known as - correct answer carcinomas
Burkitt lymphoma is most closely associated with - correct answer Epstein-Barr virus
major cause of death from leukemic disease - correct answer infection
myeloma - correct answer bence jones proteins in the urine
Renal insufficiency is common
elevated Ca levels, bone fractures common
CML chronic lymphoid leukemia - correct answer -bcr-abl translocation
-Philadelphia chromosome
-Fatigue, weight loss, abdominal discomfort, sweats
ALL Acute lymphoid leukemia - correct answer -best prognosis for long term disease free
survival
-Primarily affects children
-activity restriction with thrombocytopenia
-Common complication is infection
,-anemia, leukocytosis, thrombocytopenia, pain in long bones, fever, painless enlarged cervical
lymph nodes
non-Hodgkin lymphoma - correct answer there may be gastrointestinal tract involvement
CLL Chronic lymphoid leukemia - correct answer
AML Acute myeloid leukemia - correct answer
Hemophilia A - correct answer treatment includes Factory VIII replacement
Hemophilia B - correct answer deficiency in factor IX
Final step in clot formation - correct answer clot retraction
cause for bleeding with normal platelet cound, increased PT and INR - correct answer Vitamin K
deficiency
clotting factor deficiency from the liver
Vitamin K deficiency a newborn will present with melena, hematuria and bleeding from
umbilucs
activation of extrinsic pathway for coagulation is initiated by - correct answer Tissue
thromboplastin
PT and INR - correct answer measure integrity of extrinsic pathway
PTT - correct answer assesses the intrinsic pathway of coagulation
Von Willebrand Factor impairs - correct answer platelet adhesion to injured tissue
electrolyte imbalance causing clotting disorders - correct answer hypocalcemia
oxytocin - correct answer produced in the hypothalamic region
hormone that causes uterine and milk duct contraction, release during sexual activity
How are steroid hormones transported - correct answer diffused through cell membranes to
activate intracellular receptors
lipid soluble hormones - correct answer thyroid hormones
secondary endocrine disorder ex - correct answer pituitary hyposecretion of TSH
upregulation of target cell receptors results in - correct answer increased target cell
responsiveness to hormone
,Downregulation - correct answer decreased target cell sensitivity
Growth hormone - correct answer increases lean body mass
Stimulates liver to release IGF-1
Somatostatin supresses normal secretion of growth hormone
-infants would have normal birth length and weight
-Excess leads to acromegaly
Most endocrine hormones are water soluble and exert their effects on target cells by - correct
answer generating secondary messengers
Prolactin is inhibited by - correct answer dopamine produced by the hypothalamus
Cortisol is responsible for - correct answer regulation of immune and inflammatory reactions
After thyroidectomy pt has numbness and tingling around the mouth, what lab are we
concerned about? - correct answer low serum calcium
syntheses if thyroid hormones - correct answer inhibited by iodine deficiency
hypoparathyroidism - correct answer clinical manifestation results from decreased serum
ionized calcium
which response to an injection of ACTH indicates a primary adrenal insufficiency - correct
answer no change in serum glucocorticoid levels
Surgical removal of thyroid gland may result in
thyroid gland growing larger then normal - correct answer hyposecretion
goiter
Graves disease - correct answer -vision changes, photophobia, lid lag, tremor
, after radioactive iodine, pt will need lifelong thyroid replacement therapy
-Associated with autoantibodies of TSH receptors
Cushing syndrome - correct answer hyperglycemia common symptom, cortisol increases,
glucose intolerance
myxedema coma is associated with - correct answer hypoparathyroidism
SIADH - correct answer soaked inside
hyponatremia, edema
diabetes insipidus - correct answer inadequate ADH secretion
excessive loss of water and urine
dry inside
hyperaldosteronism - correct answer hypokalemia
type 1 diabetes - correct answer pancreatic cell destruction
type 2 diabetes mellitus - correct answer Insulin resistance and cell dysfunction
associated with nonketotic hyperosmolality
34.2 Million people in the US have this
7th leading cause of death in the US
Obesity most powerful predictor
pupil constriction is controlled by cranial nerve - correct answer III
Neurons with one dendrite and one axon are - correct answer bipolar
Unipolar - correct answer single process protruding from the cell body
Multipolar - correct answer large number of dendrtites extending from the cell body and one
axon
integrity of the blood-brain barrier is maintained in part by the CNS cells called - correct answer
astrocytes
Nursing Practice Comprehensive Questions
why does cancer come back - correct answer small areas of metastases can lie dormant only to
explode in growth later
Complete remission of leukemia is when less then 5% blasts in marrow and normal CBC values
malignant neoplasm of epithelial origin are known as - correct answer carcinomas
Burkitt lymphoma is most closely associated with - correct answer Epstein-Barr virus
major cause of death from leukemic disease - correct answer infection
myeloma - correct answer bence jones proteins in the urine
Renal insufficiency is common
elevated Ca levels, bone fractures common
CML chronic lymphoid leukemia - correct answer -bcr-abl translocation
-Philadelphia chromosome
-Fatigue, weight loss, abdominal discomfort, sweats
ALL Acute lymphoid leukemia - correct answer -best prognosis for long term disease free
survival
-Primarily affects children
-activity restriction with thrombocytopenia
-Common complication is infection
,-anemia, leukocytosis, thrombocytopenia, pain in long bones, fever, painless enlarged cervical
lymph nodes
non-Hodgkin lymphoma - correct answer there may be gastrointestinal tract involvement
CLL Chronic lymphoid leukemia - correct answer
AML Acute myeloid leukemia - correct answer
Hemophilia A - correct answer treatment includes Factory VIII replacement
Hemophilia B - correct answer deficiency in factor IX
Final step in clot formation - correct answer clot retraction
cause for bleeding with normal platelet cound, increased PT and INR - correct answer Vitamin K
deficiency
clotting factor deficiency from the liver
Vitamin K deficiency a newborn will present with melena, hematuria and bleeding from
umbilucs
activation of extrinsic pathway for coagulation is initiated by - correct answer Tissue
thromboplastin
PT and INR - correct answer measure integrity of extrinsic pathway
PTT - correct answer assesses the intrinsic pathway of coagulation
Von Willebrand Factor impairs - correct answer platelet adhesion to injured tissue
electrolyte imbalance causing clotting disorders - correct answer hypocalcemia
oxytocin - correct answer produced in the hypothalamic region
hormone that causes uterine and milk duct contraction, release during sexual activity
How are steroid hormones transported - correct answer diffused through cell membranes to
activate intracellular receptors
lipid soluble hormones - correct answer thyroid hormones
secondary endocrine disorder ex - correct answer pituitary hyposecretion of TSH
upregulation of target cell receptors results in - correct answer increased target cell
responsiveness to hormone
,Downregulation - correct answer decreased target cell sensitivity
Growth hormone - correct answer increases lean body mass
Stimulates liver to release IGF-1
Somatostatin supresses normal secretion of growth hormone
-infants would have normal birth length and weight
-Excess leads to acromegaly
Most endocrine hormones are water soluble and exert their effects on target cells by - correct
answer generating secondary messengers
Prolactin is inhibited by - correct answer dopamine produced by the hypothalamus
Cortisol is responsible for - correct answer regulation of immune and inflammatory reactions
After thyroidectomy pt has numbness and tingling around the mouth, what lab are we
concerned about? - correct answer low serum calcium
syntheses if thyroid hormones - correct answer inhibited by iodine deficiency
hypoparathyroidism - correct answer clinical manifestation results from decreased serum
ionized calcium
which response to an injection of ACTH indicates a primary adrenal insufficiency - correct
answer no change in serum glucocorticoid levels
Surgical removal of thyroid gland may result in
thyroid gland growing larger then normal - correct answer hyposecretion
goiter
Graves disease - correct answer -vision changes, photophobia, lid lag, tremor
, after radioactive iodine, pt will need lifelong thyroid replacement therapy
-Associated with autoantibodies of TSH receptors
Cushing syndrome - correct answer hyperglycemia common symptom, cortisol increases,
glucose intolerance
myxedema coma is associated with - correct answer hypoparathyroidism
SIADH - correct answer soaked inside
hyponatremia, edema
diabetes insipidus - correct answer inadequate ADH secretion
excessive loss of water and urine
dry inside
hyperaldosteronism - correct answer hypokalemia
type 1 diabetes - correct answer pancreatic cell destruction
type 2 diabetes mellitus - correct answer Insulin resistance and cell dysfunction
associated with nonketotic hyperosmolality
34.2 Million people in the US have this
7th leading cause of death in the US
Obesity most powerful predictor
pupil constriction is controlled by cranial nerve - correct answer III
Neurons with one dendrite and one axon are - correct answer bipolar
Unipolar - correct answer single process protruding from the cell body
Multipolar - correct answer large number of dendrtites extending from the cell body and one
axon
integrity of the blood-brain barrier is maintained in part by the CNS cells called - correct answer
astrocytes
