CRNA exam 4 meds 2024/2025 EXAM QUESTIONS AND
CORRECT ANSWERS ALREADY GRADED A+ PROFESSOR
VERIFIED
1. which drugs are thromboxane 2 inhibitors: Aspirin & other NSAIDS
(thromboxane normally helps vasoconstrict, allow for platelet
aggregation/activation, & helping GIIb/IIIa bind plts together through fibrinogen)
2. MOA of aspirin (acetylsalicylic acid): Irreversibly inhibits COX enzymes
from converting arachnoid acid to prostaglandins which decreases TxA2
production (decreasing platelet aggregation)
3. when should you stop taking aspirin before a surgery?: One week
4. What should you caution with Aspirin?: Reyes syndrome Allergies or
intolerances ulcers/bleeding increased PT
5. what drugs are considered to be antiplatelets:
TxA2 inhibitors ADP inhibitors
1/9
, GIIb/IIIa inhibitors
PDE3 inhibitors
6. What drugs are Thienopyridines?: Clopidogrel (plavix), Prasugrel (efficient),
Ticagrelor (brillinta),
7. What are Thienopyridines also know as: ADP or P2Y12 inhibitors
8. MOA of Clopidogrel & Prasugrel: Prodrugs that need get metabolized into
active for & then have ireversible binding to the P2Y12 receptor blocking ADP
9. MOA of ticagrelor: reversible binding to P2Y12 receptoring blocking ADP
(does not have to get metabolized into active form, direct acting)
10. What do thromboxane A2 & ADP do?: Vasoconstrict vessels, help plts
activate & aggregate, & help GpIIb/IIIa use fibrinogen to link plts together
11. what drugs inhibit ADP: Clopidogrel, Prasugrel, Ticagrelor, & Cangrelor
("grel")
12. Cangrelor: IV agent of the P2Y12 inhibitors (adjunct to PCI when havent
taken other oral agents)
13. What drugs inhibit GpIIb/IIIa: Abiximab (ReoPro), Tirofiban (aggrastat),
Eptifibatide (Integrilin)
14. MOA of Abiximab: Blocks fibrinogen from binding plts together through the
GpIIb/IIIa receptors (noncompetitive)
15. Tirofiban (aggrastat), Eptifibatide (Integrilin): Blocks fibrinogen from
binding plts together through the GpIIb/IIIa receptors
16. what do all GpIIb/IIIa inhibitors cause: thrombocytopenia
2/9
CORRECT ANSWERS ALREADY GRADED A+ PROFESSOR
VERIFIED
1. which drugs are thromboxane 2 inhibitors: Aspirin & other NSAIDS
(thromboxane normally helps vasoconstrict, allow for platelet
aggregation/activation, & helping GIIb/IIIa bind plts together through fibrinogen)
2. MOA of aspirin (acetylsalicylic acid): Irreversibly inhibits COX enzymes
from converting arachnoid acid to prostaglandins which decreases TxA2
production (decreasing platelet aggregation)
3. when should you stop taking aspirin before a surgery?: One week
4. What should you caution with Aspirin?: Reyes syndrome Allergies or
intolerances ulcers/bleeding increased PT
5. what drugs are considered to be antiplatelets:
TxA2 inhibitors ADP inhibitors
1/9
, GIIb/IIIa inhibitors
PDE3 inhibitors
6. What drugs are Thienopyridines?: Clopidogrel (plavix), Prasugrel (efficient),
Ticagrelor (brillinta),
7. What are Thienopyridines also know as: ADP or P2Y12 inhibitors
8. MOA of Clopidogrel & Prasugrel: Prodrugs that need get metabolized into
active for & then have ireversible binding to the P2Y12 receptor blocking ADP
9. MOA of ticagrelor: reversible binding to P2Y12 receptoring blocking ADP
(does not have to get metabolized into active form, direct acting)
10. What do thromboxane A2 & ADP do?: Vasoconstrict vessels, help plts
activate & aggregate, & help GpIIb/IIIa use fibrinogen to link plts together
11. what drugs inhibit ADP: Clopidogrel, Prasugrel, Ticagrelor, & Cangrelor
("grel")
12. Cangrelor: IV agent of the P2Y12 inhibitors (adjunct to PCI when havent
taken other oral agents)
13. What drugs inhibit GpIIb/IIIa: Abiximab (ReoPro), Tirofiban (aggrastat),
Eptifibatide (Integrilin)
14. MOA of Abiximab: Blocks fibrinogen from binding plts together through the
GpIIb/IIIa receptors (noncompetitive)
15. Tirofiban (aggrastat), Eptifibatide (Integrilin): Blocks fibrinogen from
binding plts together through the GpIIb/IIIa receptors
16. what do all GpIIb/IIIa inhibitors cause: thrombocytopenia
2/9
