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Bac Path exam 1 review sheet (major /important concepts to look at before exam)

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the causal agent of cholera - correct answer Vibrio cholera formidable pathogen due to toxin that causes loss of fluid control in intestines - correct answer Vibrio cholera obligate pathogen - gets inside human cells, bursts out, and causes legions - correct answer Chlamydia trachomatis - gram-negative - diplococcus - has incredible plasticity that provides evasive techniques - correct answer Neisseria gonorrhoeae what are the two intracellular pathogens that hijack actin cytoskeleton (actin-based motility) (example of convergent evolution) - correct answer Listeria monocytogenes and Shigella sonnei

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Bac Path exam 1 review sheet (major /important concepts to look at
before exam)


the causal agent of cholera - correct answer Vibrio cholera
formidable pathogen due to toxin that causes loss of fluid control in intestines - correct answer
Vibrio cholera
obligate pathogen - gets inside human cells, bursts out, and causes legions - correct answer
Chlamydia trachomatis
- gram-negative
- diplococcus
- has incredible plasticity that provides evasive techniques - correct answer Neisseria
gonorrhoeae
what are the two intracellular pathogens that hijack actin cytoskeleton (actin-based motility)
(example of convergent evolution) - correct answer Listeria monocytogenes and Shigella sonnei
Gram-positive pathogen that caused food-borne illness outbreak in ice cream - correct answer
Listeria monocytogenes
the (gram-negative) causal agent of bacillary dysentery = bloody stoo - correct answer Shigella
sonnei
what type of animals were used to study Mycobacterium Tuberculosis / Mycobacterium
marinum - correct answer guinea pig / Japenese medaka
old pathogen causing an old disease example - correct answer Mycobacterium tuberculosis
who discovered Mycobacterium tuberculosis and why was it a difficult process - correct answer
Koch - it is an acid-fast bacterium and takes 2 weeks to develop a colony on a plate
old pathogen causing new disease - correct answer Staphylococcus aureus (MRSA)
what is MRSA currently treated with - correct answer vancomycin
causal agent of malaria - correct answer Plasmodium falciparum
causal agent of syphilis - correct answer Treponema pallidum
a endspore-forming club-shaped bacterium - correct answer Corynebacterium diphtheria
causal agent of Necrotizing fasciitis- used Zebra fish as a study model - correct answer
Streptococcus pyogenes

, a major cause of death from burns and skin wounds - correct answer Streptococcus pyogenes
2 deaths were caused by this flesh-eating bacteria in Hurricane Harvey 2017 - correct answer
Streptococcus pyogenes
new pathogen causing new disease - correct answer Legionella pneumophila
new pathogen causing old disease - was mistaken as Salmonella - correct answer
Campylobacter spp.
causal agent of typhoid fever - correct answer Salmonella typhimurium
Most recent outbreak of Salmonella typhimurium - correct answer Firefly - 294 cases caused by
contaminated chorizo
Explain the difference between Salmonella enterica serovar Typhi and almonella enterica
serovar Typhimurium - correct answer Salmonella enterica serovar Typhi causes death in
humans but nothing in mice, so Salmonella enterica serovar Typhimurium is used since it causes
typhoid like symptoms in mice but only diarrhea in humans
The water-borne infection that caused 4 deaths following Hurricane Maria - correct answer
Leptospirosis
endospore-forming pathogen that was studied by Koch - correct answer Bacillus anthracis
causes stomach cancer/ulcers and used ferrets as animal model - correct answer Helicobacter
pylori
causal agent of Lyme disease - correct answer Borrelia burgdorferi
What is the main virulence factor of Borrelia burgdorferi - correct answer The fact that it
doesn't need iron scavenging genes because it uses manganese instead
an example of PCR amplification of 16S rRNA genes allowing bacterial DNA to be identified in
human samples - correct answer Tropheryma whipplei- causal agent of whipple's disease (rare
intestinal disease)
armadillos were used to study what - correct answer Mycobacterium leprae
- causal agent of otitis media (ear infections)- chinchillas used as model - correct answer
Haemophilus influenzae/Streptococcus pneumoniae
An example of a pathogen that has a single gene responsible for the virulence - correct answer
Clostridium botulinum
In septic shock, ___ acts as a toxin and leads to death - correct answer LPS
1st to discover a drug that specifically targeted bacterial cells - correct answer Gerhard Domagk

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