Test Bank for Pharmacotherapeutics for Advanced Practice: A Practical Approach, 5th Edition by Arcangelo, 9781975160593, Covering Chapters 1-56 | Includes Rationales

TestBankforPharmacotherapeuticsforAdvancedPracticeA
PracticalApproach5thEditionByVirginiaPooleArcangelo,
B




AndrewMPeterson,Veronica Wilbur,TepM.Kang/All
B B B B B B B B B




B ChaptersCovered–LatestUpdate2024.




Nursepractitionerprescriptiveauthorityisregulatedby:

1. TheNationalCouncilofStateBoardsofNursing

2. TheU.S.DrugEnforcement Administration v




3. TheStateBoardofNursingforeachstate

4. TheStateBoardofPharmacy - Correct Answer - 3. The State Board of Nursing for each state B v v v v v v v v v v v v




ThebenefitstothepatientofhavinganAdvancedPracticeRegisteredNurse(APRN)prescriberinclude:B B B




1. NursesknowmoreaboutPharmacologythanotherprescribersbecausetheytakeitbothintheirbasic
B B B B B B B B B




nursing program and in their APRN program.
B B B B B B B




2. Nursescareforthepatientfromaholisticapproachandinclude thepatient indecisionmaking B B v B




regarding their care.
B B B




3. APRNsarelesslikelyto prescribenarcoticsandothercontrolledsubstances. B




4. APRNsareabletoprescribeindependentlyinallstates,whereasaphysician'sassistantneeds tohavea v B




physician supervising their practice. - Correct Answer - 2. Nurses care for the patient from a holistic
B B B B B v v v v v v v v v v v



approach and include the patient in decision making regarding their care.
v v v v v v v v v v v




Clinicaljudgmentinprescribingincludes:

1. Factoringinthecost tothepatientofthemedicationprescribed
B B B B




2. Alwaysprescribingthenewestmedication available for thediseaseprocess B B B




3. Handingout drugsamplesto poorpatients v B B




4. Prescribingallgenericmedicationsto cutcosts - Correct Answer - 1. Factoring in the cost to the B B v v v v v v v v v v vv


patient of the medication prescribed
v v v v


1
B

,Criteriaforchoosing aneffectivedrugforadisorderinclude: v




1. Askingthe patientwhatdrugthey thinkwouldwork bestforthem
B B B B B




2. Consultingnationallyrecognizedguidelinesfordiseasemanagement

3. Prescribingmedicationsthat areavailableas samples beforewritingaprescription B B B




4. FollowingU.S.DrugEnforcementAdministration guidelinesforprescribing - Correct Answer - 2. B B B v v v vv


Consulting nationally recognized guidelines for disease management
v v v v v v




Nursepractitionerpracticemay thriveunderhealth-carereformbecauseof: B




1. Thedemonstratedabilityofnursepractitionerstocontrolcostsandimprovepatientoutcomes B B




2. Thefactthatnursepractitionerswillbeabletopracticeindependently

3. The fact thatnursepractitionerswillhave full reimbursementunderhealth-carereform
B B B B




4. Theabilityto shiftaccountabilityforMedicaidtothestatelevel - Correct Answer - 1. The
B v B B B v v v v v



demonstrated ability of nurse practitioners to control costs and improve patient outcomes
B v v v v v v v v v v v




Apatient'snutritionalintake andlaboratoryresultsreflecthypoalbuminemia.This is v B B B




critical to prescribing because:
B B B B




1. Distributionofdrugsto target tissuemay beaffected. B B B B




2. Thesolubilityofthedrugwill notmatchthe siteof absorption. B B B




3. Therewillbeless freedrugavailableto generateaneffect. v v




4. Drugs boundtoalbuminarereadilyexcretedbythekidneys. -Correct Answer - 1. Distribution of drugs to
v B B B B v v v v v v v




target tissue may be affected.
v v v v v




Drugs that haveasignificant first-pass effect:
B B B v




1. Mustbegivenbytheenteral(oral)routeonly

2. Bypassthehepaticcirculation B




3. Arerapidlymetabolizedby theliverandmayhavelittleifanydesiredaction B




2
B

,4. Areconvertedbythelivertomoreactiveandfat-solubleforms - Correct Answer - 3. Are rapidly v B v v v v v vv


metabolized by the liver and may have little if any desired action
v v v v v v v v v v v




The routeofexcretionof avolatiledrug willlikely be the:
B B B B B B




1. Kidneys

2. Lungs

3. Bileandfeces B




4. Skin - Correct Answer - 2. Lungs
v v v v v v




Medroxyprogesterone(DepoProvera)isprescribedintramuscularly(IM)tocreateastoragereservoirofthe B




drug. Storage reservoirs:
B B B




1. Assurethatthedrugwillreach its intendedtarget tissue B B B




2. Arethereasonfor givingloading doses B B




3. Increasethelengthoftime adrugis availableandactive B v




4. Aremostcommonincollagentissues - Correct Answer - 3. Increase the length of time a drug is B B B v v v v v v v v v v v v vv


available and active v v




TheNPchoosestogivecephalexinevery8hours basedonknowledgeofthedrug's: B B v




1. Propensitytogo tothetargetreceptor B B




2. Biological half-life B




3. Pharmacodynamics

4. Safetyandsideeffects-Correct Answer - 2. Biological half-life v v v v v




Azithromycindosingrequires thatthefirstday'sdosagebetwicethoseoftheother 4days ofthe prescription.
B B B B B B B B v B B




This is considered a loading dose. A loading dose:
B B B B B B B B B




1. Rapidly achievesdruglevels inthetherapeuticrange
B B




2. Requiresfour-to five-half-livestoattain v




3. Isinfluencedbyrenalfunction

4. Isdirectly relatedtothedrugcirculatingtothetargettissues - Correct Answer - 1. Rapidly achieves
B B B v v v v v vv


drug levels in the therapeutic range
v v v v v




3
B

, Thepointintimeonthedrugconcentrationcurvethatindicatesthefirstsignofa therapeuticeffectis the:
B B B B B B B B B B B B




1. Minimumadverse effect level B B B




2. Peak ofaction v




3. Onsetof action B




4. Therapeuticrange-Correct Answer - 3. Onset of action B v v v v v v




Phenytoinrequiresthatatroughlevel be drawn.Peakandtroughlevels are done: B B B B B




1. Whenthe drughas awide therapeuticrange
B B B B




2. Whenthe drugwillbe administeredforashorttimeonly
v B B B B




3. Whenthereis ahighcorrelation betweenthe doseandsaturation ofreceptorsites
B B B B B B B




4. Todetermineifadrug isinthetherapeuticrange - Correct Answer - 4. To determine if a drug is in the
v B B v v v v v v v v v v v vv


therapeutic range v




Alaboratory resultindicates thatthepeaklevelfora drug is abovetheminimum toxicconcentration. Thismeans
B B B v B B B




thatthe:
B B




1. Concentrationwill produce therapeutic effects B B B




2. Concentrationwillproduceanadverseresponse

3. Timebetweendosesmustbeshortened

4. Durationofactionofthedrugistoo long- Correct Answer - 2. Concentration will produce an adverse B B B v v v v v v v v



response
B




Drugsthatarereceptoragonistsmaydemonstratewhatproperty?

1. Irreversiblebindingto thedrugreceptorsite B B




2. Upregulationwithchronicuse

3. Desensitizationor downregulation with continuous use B B B B B




4. Inverserelationshipbetweendrugconcentrationanddrugaction- Correct Answer - 3. Desensitization or B B v v v v v v



downregulation with continuous use
v v v v




pg. 4
B