TEST BANK FOR Cellular and Molecular Immunology 10th Edition by Abul K. Abbas, Andrew H. Lichtman ISBN: 978-0323757485 COMPLETE GUIDE ALL CHAPTERS COVERED WITH RATIONALES 100% VERIFIED A+ GRADE ASSURED!!!!!NEW LATEST UPDATE!!!!!

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Cellular and Molecular Immunology
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Abul Abbas, Andrew Lichtman, and Shiv Pillai
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10th Edition
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,Table of Contents
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Chapter 01 Properties and Overview of Immune Responses
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Chapter 02 Cells and Tissues of the Immune System
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Chapter 03 Leukocyte Circulation and Migration Into Tissues
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Chapter 04 Innate Immunity
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Chapter 05 Antibodies and Antigens
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Chapter 06 Antigen Presentation to T Lymphocytes and the Functions of Major
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Histocompatibility Complex Molecules ap ap 20
Chapter 07 Immune Receptors and Signal Transduction
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Chapter 08 Lymphocyte Development and Antigen Receptor Gene Rearrangement
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Chapter 09 Activation of T Lymphocytes
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Chapter 10 Differentiation and Functions of CD4+ Effector T Cells
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Chapter 11 Differentiation and Functions of CD8+ Effector T Cells
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Chapter 12 B Cell Activation and Antibody Production
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Chapter 13 Effector Mechanisms of Humoral Immunity
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Chapter 14 Specialized Immunity at Epithelial Barriers and in Immune Privileged Tissues
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Chapter 15 Immunologic Tolerance and Autoimmunity
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Chapter 16 Immunity to Microbes
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Chapter 17 Transplantation Immunology
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Chapter 18 Tumor Immunology
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Chapter 19 Hypersensitivity Disorders
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Chapter 20 Allergy
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Chapter 21 Primary and Acquired Immunodeficiencies
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,Chapter 01: Properties and Overview of Immune Responses
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Abbas, Lichtman, and Pillai: Cellular and Molecular Immunology, 10th Edition
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MULTIPLE CHOICE ap




1. The principal function of the immune system is:
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a. Defense against cancer ap ap



b. Repair of injured tissues ap ap ap



c. Defense against microbial infections ap ap ap



d. Prevention of inflammatory diseases ap ap ap



e. Protection against environmental toxins ap ap ap




ANS: C a p



The immune system has evolved in the setting of selective pressures imposed by microbial i
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nfections. Although immune responses to cancer may occur, the concept that “immunosurv
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eillance” against cancer is a principal function of the immune system is controversial. Repai
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r of injured tissues may be a secondary consequence of the immune responses and inflamm
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ation. Although the immune system has regulatory features that are needed to prevent exces
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sive inflammation, prevention of inflammatory diseases is not a primary function. The imm
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une system can protect against microbial toxins, but it generally does not offer protection ag
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ainst toxins of nonbiologic origin.
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2. Which of the following infectious diseases was prevented by the first successful
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vaccination?
a. Polio
b. Tuberculosis
c. Smallpox
d. Tetanus
e. Rubella
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In 1798, Edward Jenner reported the first intentional successful vaccination, which was aga
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inst smallpox in a boy, using material from the cowpox pustules of a milkmaid. In 1980, smal
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lpox was reported to be eradicated worldwide by a vaccination program. Effective vaccines
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against tetanus toxin, rubella virus, and poliovirus were developed in the 20th century and a
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re widely used. There is no effective vaccine against Mycobacterium tuberculosis.
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3. Which of the following is a unique property of the adaptive immune system?
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a. Highly diverse repertoire of specificities for antigens ap ap ap ap ap ap



b. Self-nonself discrimination ap



c. Recognition of microbial structures by both cell-associated and soluble receptors ap ap ap ap ap ap ap ap ap



d. Protection against viral infections ap ap ap



e. Responses that have the same kinetics and magnitude on repeated exposure to the s ap ap ap ap ap ap ap ap ap ap ap ap ap



ame microbe ap




ANS: a p A

, Highly diverse repertoires of specificities for antigens are found only in T and B lymphocyt
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es, which are the central cellular components of the adaptive immune system. Both the innat
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e and the adaptive immune systems use cell-
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associated and soluble receptors to recognize microbes, display some degree of self-
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nonself discrimination, and protect against viruses. On repeated exposure to the same micro
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be, the adaptive immune response becomes more rapid and of greater magnitude; this is the
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manifestation of memory. ap ap




4. Antibodies and T lymphocytes are the respective mediators of which two types of i
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mmunity?
a. Innate and adaptive ap ap



b. Passive and active ap ap



c. Specific and nonspecific ap ap



d. Humoral and cell-mediated ap ap



e. Adult and neonatal ap ap




ANS: D a p



Both B and T lymphocytes are principal components of adaptive immunity. B lymphocytes p
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roduce antibodies, which are the recognition and effector molecules of humoral immune resp
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onses to extracellular pathogens. T cells recognize and promote eradication of intracellular p
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athogens in cell- ap ap



mediated immunity. Passive and active immunity both can be mediated by either B or T lymp
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hocytes. Specific immunity is another term for adaptive immunity. Both B and T lymphocyte
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s participate in adult adaptive immunity but are still developing in the neonatal period.
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5. The two major functional classes of effector T lymphocytes are:
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a. Helper T lymphocytes and cytotoxic T lymphocytes ap ap ap ap ap ap




b. Natural killer cells and cytoWtoWxW
ic.TTlB
yS
mMph.oW
cyStes ap ap ap ap



c. Memory T cells and effector T cells ap ap ap ap ap ap



d. Helper cells and antigen-presenting cells ap ap ap ap



e. Cytotoxic T lymphocytes and target cells ap ap ap ap ap




ANS: A a p



T cells can be classified into effector subsets that perform different effector functions. Most e
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ffector T cells are either helper T lymphocytes, which enhance the responses of other immu
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ne cells, including phagocytes and B cells, to infections, or cytotoxic T lymphocytes, which
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directly kill infected cells. Natural killer cells are not T lymphocytes.
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Antigen-presenting cells usually are not T cells. Memory T cells are not effector T cells. ap ap ap ap ap ap ap ap ap ap ap ap ap ap




6. Which of the following cell types is required for all adaptive humoral immune responses?
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a. Natural killer cells ap ap



b. Dendritic cells ap



c. Cytolytic T lymphocytes ap ap



d. B lymphocytes ap



e. Helper T lymphocytes ap ap




ANS: D a p



Humoral immune responses are antibody- ap ap ap ap



mediated immune responses, and all antibodies are made by B lymphocytes and no other
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cell type. ap