NR566 / NR 566 Midterm Exam Study Guide (Latest
): Advanced Pharmacology for Care of the
Family - Chamberlain College
Latest examination Study Guide 2023
121Week:
- Things21to21know21about21each21of21the21major21antibiotic21drug21classes:2 1
● Examples:
○ Bactericidal21agents:21“BANG21Q21R.I.P”21-21Beta-
lactams,21Aminoglicosides,21Nitroimidazoles21(Metronidazole),21Glycopepti
des21(Vancomycin),21Quinolones,21Rifampicin,21Polymyxins21(Colistin)
○ Bacteriostatic21agents:21“Ms.21Colt”21-
21Macrolides,21Sulfonamides,21Chloramphenicol,21Oxazolidinones,21Lincosamid
es21(Clindamycin),21Tetracyclines
Bactericidal21antibiotics21kill21bacteria21directly,21and21bacteriostatic21a
ntibiotics21stop/weaken21bacteria21from21growing.to21enable21the21immune21sys
tem21to21take21hold21of21infection
-Things21to21know21 about21 each21 of21the21 major21 antibiotic21drug21classes21 (MAKE21FLASHCARDS)
,● Aminoglycosides
● Cephalosporins
● Tetracyclines
● Penicillins
● Sulfonamides
● Fluoroquinolones
, ● Macrolides
● Carbapenems
● Lincosamides
● Glycopeptides
o Examples
o Contraindications21and21high-risk21patients
o Know21examples21of21each21of21the21major21antibiotic21drug21classes.
o Monitoring21needs
o Which21ones21require21renal21dosing21adjustments21and21how21much21(i.e.,2125%,2150%,21etc.)
o Patient21education
o Lifespan21considerations21including21pregnancy21o21Indications21for21use
Considerations:2 1
● Renal/hepatic21function:21doses21may21need21to21be21reduced.21Consider21creatinine21clearance.
● Age:21dose21adjustments21may21be21required21for21pediatric21and21geriatric21patient
s-21weight-21based21may21be21appropriate.
● Pregnancy21and21lactation:21Be21aware21of21teratogenic21effects21of21certain2
1classes21of21medications
● Recent21antibiotic21use:21Be21aware21of21possible21drug-resistant21bacteria
● Exposure21history:21travel,21congregate21care21settings,21close21contacts
● Monitoring21needs
○ Next,21consider21the21syndrome,21or21presenting21illness.21--
21What21system21is21impacted?21How21aggressive21is21the21infection?21Consider
21non-bacterial21causes21of21symptoms21(i.e.21viral,21fungal,21or21non-
infections)21Carefully21examine21the21clinical21presentation21of21illness.
● Which21ones21require21renal21dosing21adjustments21and21how21much21(i.e.,2125%,2150%,21etc.
):
VII.21Precautions:21Antibiotics
A. Antibiotics21that21require21NO21renal21dose21adjustment
1. Azithromycin
2. Ceftriaxone
3. Clindamycin
4. Doxycyline
5. Linezolid
6. Moxifloxacin
7. Nafcillin
8. Rifampin
, B. Agents21to21avoid21in21severe21Chronic21Kidney21Disease
1. Penicillin21G21(Myoclonus,21Seizures,21coma21risk)
2. Imipenem21with21cilastin21(Seizure21risk);21Meropenem21safe
3. Tetracycline21(exacerbates21 Uremia);21Doxycycline21 safe
4. Nitrofurantoin21 (peripheral21 neurotoxicity)
5. Aminoglycosides21(or21close21level21monitoring21if21used)
C. Amoxicillin
): Advanced Pharmacology for Care of the
Family - Chamberlain College
Latest examination Study Guide 2023
121Week:
- Things21to21know21about21each21of21the21major21antibiotic21drug21classes:2 1
● Examples:
○ Bactericidal21agents:21“BANG21Q21R.I.P”21-21Beta-
lactams,21Aminoglicosides,21Nitroimidazoles21(Metronidazole),21Glycopepti
des21(Vancomycin),21Quinolones,21Rifampicin,21Polymyxins21(Colistin)
○ Bacteriostatic21agents:21“Ms.21Colt”21-
21Macrolides,21Sulfonamides,21Chloramphenicol,21Oxazolidinones,21Lincosamid
es21(Clindamycin),21Tetracyclines
Bactericidal21antibiotics21kill21bacteria21directly,21and21bacteriostatic21a
ntibiotics21stop/weaken21bacteria21from21growing.to21enable21the21immune21sys
tem21to21take21hold21of21infection
-Things21to21know21 about21 each21 of21the21 major21 antibiotic21drug21classes21 (MAKE21FLASHCARDS)
,● Aminoglycosides
● Cephalosporins
● Tetracyclines
● Penicillins
● Sulfonamides
● Fluoroquinolones
, ● Macrolides
● Carbapenems
● Lincosamides
● Glycopeptides
o Examples
o Contraindications21and21high-risk21patients
o Know21examples21of21each21of21the21major21antibiotic21drug21classes.
o Monitoring21needs
o Which21ones21require21renal21dosing21adjustments21and21how21much21(i.e.,2125%,2150%,21etc.)
o Patient21education
o Lifespan21considerations21including21pregnancy21o21Indications21for21use
Considerations:2 1
● Renal/hepatic21function:21doses21may21need21to21be21reduced.21Consider21creatinine21clearance.
● Age:21dose21adjustments21may21be21required21for21pediatric21and21geriatric21patient
s-21weight-21based21may21be21appropriate.
● Pregnancy21and21lactation:21Be21aware21of21teratogenic21effects21of21certain2
1classes21of21medications
● Recent21antibiotic21use:21Be21aware21of21possible21drug-resistant21bacteria
● Exposure21history:21travel,21congregate21care21settings,21close21contacts
● Monitoring21needs
○ Next,21consider21the21syndrome,21or21presenting21illness.21--
21What21system21is21impacted?21How21aggressive21is21the21infection?21Consider
21non-bacterial21causes21of21symptoms21(i.e.21viral,21fungal,21or21non-
infections)21Carefully21examine21the21clinical21presentation21of21illness.
● Which21ones21require21renal21dosing21adjustments21and21how21much21(i.e.,2125%,2150%,21etc.
):
VII.21Precautions:21Antibiotics
A. Antibiotics21that21require21NO21renal21dose21adjustment
1. Azithromycin
2. Ceftriaxone
3. Clindamycin
4. Doxycyline
5. Linezolid
6. Moxifloxacin
7. Nafcillin
8. Rifampin
, B. Agents21to21avoid21in21severe21Chronic21Kidney21Disease
1. Penicillin21G21(Myoclonus,21Seizures,21coma21risk)
2. Imipenem21with21cilastin21(Seizure21risk);21Meropenem21safe
3. Tetracycline21(exacerbates21 Uremia);21Doxycycline21 safe
4. Nitrofurantoin21 (peripheral21 neurotoxicity)
5. Aminoglycosides21(or21close21level21monitoring21if21used)
C. Amoxicillin
