Test Bank for Abrams’ Clinical Drug Therapy: Rationales for Nursing Practice, 13th Edition (Frandsen, 2025), Chapter 1-61 | All Chapters

Test Bank For Abrams’ Clinical Drug Therapy R
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ationales for Nursing Practice 13th Edition (Vers
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ion 2024/2025) Geralyn Frandsen
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,Chapter 1, The Foundation of Pharmacology: Quality and Safety
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1. A woman diagnosed with obsessive–
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compulsive disorder has been prescribed oral paroxetine hydrochloride. What is
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the expected effect for this prescription?
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A. Curative effect on symptoms hk hk hk



B. Systemic effect on symptoms hk hk hk



C. Local effect on symptoms hk hk hk



D. Parenteral effect on symptoms hk hk hk




ANS: B h k h k



Rationale: Drugs that produce systemic effects are taken into the body, circulated through
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the bloodstream to their sites of action in various body tissues, and eventually eliminated
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from the body. Curative agents are given to cure a disease process. In this
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case, paroxeti ne hydrochloride will control the symptoms but not cure the disorder.
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Drugs with local eff ects, such as sunscreen and local anesthetics, act mainly at the site
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of application. Paroxet ine hydrochloride is not administered parenterally. Parenteral
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agents are administered sub cutaneously, intramuscularly, or intravenously.
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PTS: 1 REF: p. 3, Introduction OBJ: 1 hk hk



NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral
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Therapi es TOP:
hk Chapter: 1: The Foundation of Pharmacology: Quality and
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Safety KEY: Integrated Process: Nursing Process
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BLM: Cognitive Level: Understand h k NOT: Multiple Choice
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2. A client has been prescribed an antibiotic. This medication is a naturally
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occurring substance that has been cheG
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for this type o
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f medication?
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A. Synthetic drug hk



B. Semisynthetic drug hk



C. Biotechnology drug hk



D. Prototype drug hk




ANS: B h k h k



Rationale: Semisynthetic drugs (e.g., many antibiotics) are naturally occurring substances
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that have been chemically modified. Synthetic drugs are more standardized in their
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chemic al characteristics, more consistent in their effects, and less likely to produce
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allergic react ions. Biotechnology drugs involve manipulating DNA and RNA and
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recombining genes i nto hybrid molecules that can be inserted into living organisms.
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Prototype drugs are the f irst drug of a particular group to be developed.
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PTS: 1 REF: p. 3, Drug Sources OBJ: 1 hk hk hk



NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral
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Therapi es TOP:
hk Chapter: 1: The Foundation of Pharmacology: Quality and
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Safety KEY: Integrated Process: Nursing Process
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BLM: Cognitive Level: Understand h k NOT: Multiple Choice
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3. Which classification applies to morphine?
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A. Central nervous system depressant hk hk hk



B. Central nervous system stimulant hk hk hk

,
, C. Anti-inflammatory
D. Antihypertensive
ANS: A h k h k



Rationale: Drugs are classified according to their effects on particular body systems, their
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therapeutic uses, and their chemical characteristics. Morphine is classified as a central ne
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rvous system depressant and will produce this effect in the client. A central nervous
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syste m stimulant increases attention and raises mood. An anti-
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inflammatory agent decreases inflammation at the site of tissue or joint inflammation. An
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antihypertensive agent reduces blood pressure.
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PTS: 1 REF:
p. 3, Drug Classifications and Prototypes OBJ: 1
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NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral
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Therapi es TOP:
hk Chapter: 1: The Foundation of Pharmacology: Quality and
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Safety KEY: Integrated Process: Nursing Process
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BLM: Cognitive Level: Remember h k NOT: Multiple Choice
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4. A client is administered amoxicillin. The generic name of this medication belongs to
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whi ch drug group?
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A. Selective serotonin reuptake inhibitors hk hk hk



B. Diuretics
C. Penicillins
D. ACE inhibitors hk




ANS: C h k h k



Rationale: The generic namGeRoAfDteE
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eOdrug group (e.g., drugs with generic
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nam es ending in ―cillin‖ are penicillins). Selective serotonin reuptake inhibitors are
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medicatio
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ns that have antidepressant effects; SSRI is a broad classification, not a generic name.
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Diur etics are medications that increase urine output; diuretic is a broad classification,
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not a ge neric name. ACE inhibitor is the broad classification for the angiotensin receptor
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blockers, not the generic name.
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PTS: 1 REF: p. 3, Drug Names OBJ: 2
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NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral
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Therapi es TOP:
hk Chapter: 1: The Foundation of Pharmacology: Quality and
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Safety KEY: Integrated Process: Nursing Process
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BLM: Cognitive Level: Understandh k NOT: Multiple Choice
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5. The administration of diphenhydramine is regulated by which U.S. government agency?
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A. Public Health Service hk hk



B. Federal Trade Commission hk hk



C. Occupational Safety and Health Administration hk hk hk hk



D. Food and hk




Drug Administration ANS: D
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