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ANCC Medical-Surgical Certification – Practice Questions and Answers | High-Yield Exam Preparation for Registered Nurses (2025 Edition)

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This document contains a focused collection of multiple-choice practice questions and answers tailored to the ANCC Medical-Surgical Nursing Certification Exam. It covers core clinical topics such as cardiovascular, respiratory, gastrointestinal, neurological, endocrine, and musculoskeletal systems, along with professional roles, safety, patient education, and legal-ethical standards. Each question is accompanied by the correct answer to support effective self-assessment and learning. The content aligns with current ANCC guidelines and is ideal for nurses preparing for certification or clinical review.

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‭ NCC Medical-Surgical Certification Practice Questions‬
A
‭and Answers‬‭.‬
‭It includes:‬
‭●‬ M ‭ ultiple-choice questions‬‭covering a wide range of medical-surgical‬
‭nursing topics, including cardiovascular, gastrointestinal, surgical care‬
‭(pre-operative, intra-operative, and post-operative), integumentary, and‬
‭reproductive health.‬
‭●‬ ‭Correct answers clearly indicated in bold‬‭for easy identification.‬
‭●‬ ‭Rationales for selected answers‬‭, providing explanations for why a‬
‭particular option is correct, which is valuable for learning and‬
‭understanding.‬
‭●‬ ‭Definitions and explanations of key medical terms, signs, triads, and‬
‭nursing concepts‬‭,‬‭such as:‬
‭○‬ ‭Specific clinical signs‬‭(e.g., McBurney's point, Murphy's sign,‬
‭Homan's sign, Jar sign/Markle sign, Brudzinski sign, Kernig's‬
‭sign, Chvostek's sign, Trousseau's sign, Levine sign).‬
‭○‬ ‭Medical triads‬‭(e.g., Beck's triad, Charcot's triad for MS and‬
‭cholangitis, Cushing's triad, Bergman's triad).‬
‭○‬ ‭Breathing patterns‬‭(e.g., Kussmaul breathing).‬
‭○‬ ‭Nursing and medical frameworks‬‭(e.g., CAGE, Braden score,‬
‭PUSH score, Confusion Assessment Method (CAM), Nursing‬
‭Process, Piaget's stages of Cognitive Development, Bloom's‬
‭Taxonomy, 5 Rights of Delegation, Triple H therapy).‬
‭○‬ ‭Types of immunity‬‭,‬‭cancer statistics, and medication side‬
‭effects‬

,‭ . A nurse is reviewing the medical record of a client who is receiving‬
1
‭heparin therapy for treatment of DVT. Which of the following‬
‭interventions should the nurse anticipate taking if the client's aPTT is‬
‭96 seconds?‬‭a. Increase the heparin infusion flow‬‭rate by 2 mL/hr b.‬
‭continue to monitor the heparin infusion as prescribed c. request a‬
‭prothrombin time‬‭d. stop the heparin infusion‬

‭ ationale: An aPTT of 96 seconds is well above the therapeutic range‬
R
‭(typically 60-80 seconds for heparin therapy), indicating a high risk for‬
‭bleeding. The nurse's priority is to stop the infusion to prevent hemorrhage‬
‭and then notify the provider.‬



‭ . A nurse is providing teaching for a client who is 2 days post-op‬
2
‭following a heart transplant. Which of the following statements should‬
‭the nurse include in the teaching?‬‭a. "you may no‬‭longer be able to‬
‭feel chest pain."‬‭b. "your level of activity tolerance‬‭will not change." c.‬
‭"after 6 months, you will no longer need to restrict your sodium intake." d.‬
‭"you will be able to stop taking immunosuppressants after 12 months."‬

‭ ationale: The transplanted heart is denervated, meaning it's no longer‬
R
‭connected to the central nervous system. As a result, the client will not‬
‭experience angina (chest pain) as a symptom of ischemia.‬



‭ . A nurse is assessing a client in the emergency room who has a‬
3
‭bradydysrhythmia. Which of the following findings should the nurse‬
‭expect?‬‭a. confusion‬‭b. friction rub c. hypertension d. dry skin‬

‭ ationale: A slow heart rate (bradydysrhythmia) can lead to decreased‬
R
‭cardiac output and reduced cerebral perfusion, causing symptoms like‬
‭confusion, dizziness, and syncope.‬



‭ . A nurse in the emergency department is caring for a client who had‬
4
‭an anterior MI. The client's history reveals she is 1 week post-op open‬

,‭ holecystectomy. The nurse should recognize that which of the‬
c
‭following interventions is contraindicated?‬‭a. administering IV morphine‬
‭sulfate b. administering oxygen at 2 L/min via nasal cannula c. helping the‬
‭client to the bedside commode‬‭d. assisting with thrombolytic‬‭therapy‬

‭ ationale: Thrombolytic therapy dissolves clots but is contraindicated in‬
R
‭clients who have had recent surgery (within 3 weeks) due to the high risk of‬
‭severe bleeding at the surgical site.‬



‭ . A nurse is caring for a client who has endocarditis. Which of the‬
5
‭following findings should the nurse recognize as a potential‬
‭complication?‬‭a. ventricular depolarization b. Guillain-Barre‬‭syndrom c.‬
‭myelodysplastic syndrome‬‭d. Valvular disease‬

‭ ationale: Endocarditis is an infection of the heart's inner lining and valves.‬
R
‭The formation of vegetations on the valves can lead to significant damage‬
‭and valvular dysfunction, such as stenosis or regurgitation.‬



‭ . A nurse is caring for a client who presents to the ER with a BP of‬
6
‭254/138 mmHg. The nurse recognizes that the client is in a‬
‭hypertensive crisis. Which of the following actions should the nurse‬
‭take first?‬‭a. obtain blood samples for laboratory‬‭testing b. Tell the client to‬
‭report vision changes c. Place the head of the bed at 45 degrees‬‭d. initiate‬
‭an IV‬

‭ ationale: The priority in a hypertensive crisis is to establish IV access to‬
R
‭administer medication to rapidly and safely lower the blood pressure and‬
‭prevent organ damage. While other actions are important, establishing a‬
‭line is the first step in intervention.‬



‭ . A nurse is caring for a client who has HF and is experiencing AF.‬
7
‭The nurse should plan to monitor for and report which of the‬
‭following findings to the provider immediately?‬‭a.‬‭slurred speech‬‭b.‬
‭irregular pulse c. dependent edema d. persistent fatigue‬

‭Rationale: Slurred speech can be a sign of an embolic stroke, a serious‬

, c‭ omplication of atrial fibrillation where a clot forms in the heart and travels‬
‭to the brain. This is a medical emergency and must be reported‬
‭immediately.‬



‭ . A nurse is assessing a client who has left-sided HF. Which of the‬
8
‭following manifestations should the nurse expect to find?‬‭a. inc‬
‭abdominal girth‬‭b. weak peripheral pulses‬‭c. jugular‬‭vein distention d.‬
‭dependent edema‬

‭ ationale: Left-sided heart failure leads to a decrease in cardiac output,‬
R
‭resulting in diminished peripheral perfusion. This can be manifested as‬
‭weak peripheral pulses, cool extremities, and fatigue.‬



‭ . A nurse is caring for a client who is being treated for HF and has‬
9
‭prescriptions for digoxin and furosemide. The nurse should plan to‬
‭monitor for which of the following as an adverse effect of these‬
‭medications?‬‭a. SOB‬‭b. lightheadedness‬‭c. dry cough‬‭d. metallic taste‬

‭ ationale: Furosemide is a diuretic that can cause hypovolemia, leading to‬
R
‭orthostatic hypotension and symptoms like lightheadedness or dizziness.‬
‭Digoxin toxicity can also cause dizziness.‬



‭ 0. A nurse is monitoring a client following coronary artery bypass‬
1
‭graft surgery. Which of the following findings can indicate cardiac‬
‭tamponade?‬‭a. sternal instability b. inc WBC count‬‭c. BP 140/82 mmHg‬
‭on inspiration and 154/90 mmHg on expiration‬‭d. sinus‬‭rhythm with‬
‭occasional premature atrial contraction and HR 88/min‬

‭ ationale: This finding, known as pulsus paradoxus, is a key sign of‬
R
‭cardiac tamponade, where the blood pressure drops significantly on‬
‭inspiration due to pressure on the heart. It indicates a medical emergency.‬



‭ 1. A nurse is preparing a client for coronary angiography. The nurse‬
1
‭should report which of the following findings to the provider prior to‬

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