Nurs 502 Exam 2 Questions with Detailed Verified Answers

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Nurs 502 Exam 2 Questions with
Detailed Verified Answers

Question: The normal platelet count is
Answer: 150-300,000


Question:Platelets are formed by
Answer: Megakaryocytes in the bone marrow


Question:When a vessel is damaged, what begins the clotting process?
Answer: Adherence of platelets to the vessel wall


Question:In what 3 conditions will you see an increase in platelet count?
Answer: 1.) Active bleeding, 2.) Postsplenectomy, 3.) Myeloproliferative
diseases


Question:In what conditions is the platelet count decreased?
Answer: DIC, TTP, HIT, ITP, AND drugs; EDTA-DEPENDENT agglutination,
infection, ETOH


Question:The intrinsic pathway and extrinsic pathway are part of what?
Answer: The coagulation cascade


Question:What is a normal PT time?
Answer: 11-14 Sec

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Question:What does the PT/INR evaluate?
Answer: The extrinsic and common pathway.


Question:What is the PT/INR most sensitive to?
Answer: the vitamin K-dependent clotting factors 2, 7, 9, and 10


Question:What do we use the PT/INR for?
Answer: To monitor Coumadin therapy


Question:What replaces the PT for better standardization in thromboplastin
reagents worldwide?
Answer: The INR


Question:In which conditions would you expect to see an elevation of the
INR?
Answer: Liver disease; Coumadin therapy; DIC; Hereditary factor deficiencies
in 10, 5, 7, and 1; massive blood transfusions


Question:What is the normal partial thromboplastin time?
Answer: 26-34 Sec


Question:What does the PTT evaluate?
Answer: The intrinsic and common pathway


Question:What drug therapy is the PTT used to monitor?
Answer: Heparin therapy

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Question:Which pts can a PTT NOT be used in to monitor heparin?
Answer: Pts with lupus anticoagulant


Question:What must be used to monitor heparin therapy in a pt with lupus
anticoagulant?
Answer: Factor 10 A levels


Question:True or false, Heparin contamination from lines can give falsely
elevated PTT.
Answer: True


Question:In which conditions would you see an increased PTT?
Answer: Deficiency in specific coagulation factors in the intrinsic pathway
except for factor 13, DIC, Nonspecific inhibitor (lupus anticoagulant), Heparin,
Coumadin, and direct thromboplastin inhibitors


Question:What is the normal levels of fibrinogen?
Answer: 150-400 mg/dL


Question:Where is fibrinogen synthesized?
Answer: In the liver


Question:What is fibrinogen involved in?
Answer: Forming the clot during secondary hemostasis


Question:What is fibrinogen considered?

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Answer: An acute phase reactant


Question:When is fibrinogen increased?
Answer: In inflammatory states, Smoking, and Pregnancy


Question:When is fibrinogen decreased?
Answer: Liver disease, DIC, thrombolytic Rx, and Hereditary
dysfibrinogenemia


Question:What is the normal value for D-Dimer?
Answer: Less than 500


Question:Someone who can climb a flight of stairs or walk up the hill would
be considered to be at what level a functional capacity?
Answer: 4 METs or above


Question:What does the D-Dimer represent?
Answer: The fibrin degradation of a blood clot after fibrinolysis


Question:When is the D-Dimer increased?
Answer: In DVT, DIC, PE, and Malignancy


Question:True or false? The D-Dimer has a high sensitivity and low specificity
Answer: True


Question:A negative D-Dimer test r/o which conditions?
Answer: PE, DVT