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Treatment Protocols for Kawasaki Disease

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This document provides a comprehensive summary of the current treatment protocols for Kawasaki Disease, a critical pediatric vasculitis with potential cardiac complications. Ideal for medical students, pediatric residents, nursing students, and healthcare professionals preparing for exams or clinical rotations.

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Healthcare Nursing
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Healthcare nursing

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Treatment Protocols for Kawasaki Disease
Kawasaki Disease Stages - Acute and convalescent stages with specific treatments.



Long-term Therapy for Coronary Abnormalities - Aspirin 3-5 mg/kg daily; Clopidogrel 1 mg/kg.



Methylprednisolone for Poor Response - 30 mg/kg/day for 3 days if IVIG fails.



Pediatric Cardiologist Role - Supervises fibrinolytic therapy for acute coronary issues.



Re-treatment for IVIG Resistance - Another 2g/kg IVIG dose for resistant patients.



Warfarin or LMWH - Added for high-risk thrombosis patients



Acute Coronary Thrombosis Treatment - Fibrinolytic therapy with tPA under cardiologist
supervision.



Aspirin Dosage in Acute Stage - 80-100 mg/kg/day divided every 6 hours orally.



Aspirin Dosage in Convalescent Stage - 3-5 mg/kg once daily for 6-8 weeks.



Aspirin for Aneurysm Patients - Indefinite aspirin for patients with solitary aneurysms.



Clopidogrel Maximum Dose - Maximum 75 mg/day for Kawasaki patients.



Coronary Artery Abnormalities (CAA) - Increased risk with persistent fever after IVIG.

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