ANSWERS 100% SOLVED
, Prescriptive Authority - ANSWERlegal route to prescribe independently and without
limitation
Parts of a prescription - ANSWER- prescriber name
- license number
- contact information
- DEA number (prescriber and supervising)
- patient name
- DOB
- allergies
- name of medication
- indication
- strength
- frequency
- signature
SIG - ANSWER"let it be labeled"; instructions for the prescription
Pharmacokinetics - ANSWERthe study of the drug movement throughout the body
Ways for drugs to cross the cell membrane - ANSWER1. Channels
2. Pore transport systems - P-glycoprotein system
3. Direct penetration
Absorption - ANSWERthe drug's movement from the site of administration into the
blood
Factors that affect absorption: - ANSWERrate of dissolution, surface area, blood flow,
lipid solubility, pH partitioning
pH partitioning or ion trapping - ANSWERdrug molecules tend to accumulate on the
side of the membrane where pH most favors ionization - i.e. Acidic drugs accumulate on
the alkaline side, and basic drugs accumulate on the acidic side
Distribution - ANSWERthe drug's movement from the blood into the interstitial space of
tissues and from there into the cells
Factors that affect distribution: - ANSWERcirculation, membrane permeability, protein
binding
Metabolism (biotransformation) - ANSWERenzymatically mediated alteration of drug
structure