PHARMACOLOGY EXAM 1
LOURDES CRNA 2025 QUESTIONS
AND ANSWERS
pharmacology - ....ANSWER ...-study of effect of chemicals on living tissue
- has many subdivisions
pharmacokinetis - ....ANSWER ...-study of absorption, distribution, metabolism
and excretion of drugs
- what body does to drug
pharmaceutics - ....ANSWER ...-the formulation and preparation of drugs.
pharmacoeconomics - ....ANSWER ...-study of economic impact of drugs
toxicology - ....ANSWER ...-study of harmful effects of chemicals
pharmacognosy - ....ANSWER ...-study of medicinal uses of naturally occurring
compounds
- drugs from a plant
pharmacy - ....ANSWER ...-preparation and dispensing of drugs
pharmacogenetics - ....ANSWER ...-genetic influences by and on drugs
....FOR STUDY PURPOSES...©️2025 ALL RIGHTS RESERVED... 1
,pharmacodynamics - ....ANSWER ...-physiological and biochemical mechanism of
action of drugs
- what drug does to body
pharmacogenomics - ....ANSWER ...-identifies discrete genetic differences among
individuals that play a critical role in drug response
pharmacoepidemiology - ....ANSWER ...-study of the use and effects of drugs on
large groups of people
if give a drug and HR goes down to 40 this is an example of - ....ANSWER ...-
pharmacodynamic effect
if give a drug and liver metabolizes 80% of it this is an example of -
....ANSWER ...-pharmacokinetic effect
receptor theory - ....ANSWER ...-pharmacodynamics
- dug receptor is macromolecular complex which acts as site of action for a drug
- are usually proteins involved in production of normal cellular function
- ex. lock and key --> stereospecificity --> must have right shape and size for ligand to fit
in receptor
cant have a receptor without an - ....ANSWER ...-endogenous chemical
receptors are normally made up of - ....ANSWER ...-proteins
Ligand - ....ANSWER ...-chemical substances that bind to specific receptor
2 types of ligands - ....ANSWER ...-1) agonist
....FOR STUDY PURPOSES...©️2025 ALL RIGHTS RESERVED... 2
, 2) antagonist
agonist - ....ANSWER ...-bind to a receptor and Stimulate the function that
receptor serves
- mimics action of endogenous ligand (such as hormone or neurotransmitter) that binds
to same receptor
antagonist - ....ANSWER ...-bind to a receptor and block the function that receptor
serves
- has affinity for receptor but no efficacy
competitive binding - ....ANSWER ...-reversible (most drugs)
- ex: morphine vs narcan
noncompetitive binding - ....ANSWER ...-nonreversible
- ex: aspirin
allosteric agonist (activators) - ....ANSWER ...-enhance signal, respectively, by
binding to allosteric sites that influence signal transmission
-binds to one site but works somewhere else
allosteric antagonist - ....ANSWER ...-blocks signal, respectively, by binding to
allosteric sites that influence signal transmission
ED50 - ....ANSWER ...-Effective dose in 50% of population
TD50 - ....ANSWER ...-Toxic dose in 50% of population
LD50 - ....ANSWER ...-Lethal dose in 50% of population
....FOR STUDY PURPOSES...©️2025 ALL RIGHTS RESERVED... 3
LOURDES CRNA 2025 QUESTIONS
AND ANSWERS
pharmacology - ....ANSWER ...-study of effect of chemicals on living tissue
- has many subdivisions
pharmacokinetis - ....ANSWER ...-study of absorption, distribution, metabolism
and excretion of drugs
- what body does to drug
pharmaceutics - ....ANSWER ...-the formulation and preparation of drugs.
pharmacoeconomics - ....ANSWER ...-study of economic impact of drugs
toxicology - ....ANSWER ...-study of harmful effects of chemicals
pharmacognosy - ....ANSWER ...-study of medicinal uses of naturally occurring
compounds
- drugs from a plant
pharmacy - ....ANSWER ...-preparation and dispensing of drugs
pharmacogenetics - ....ANSWER ...-genetic influences by and on drugs
....FOR STUDY PURPOSES...©️2025 ALL RIGHTS RESERVED... 1
,pharmacodynamics - ....ANSWER ...-physiological and biochemical mechanism of
action of drugs
- what drug does to body
pharmacogenomics - ....ANSWER ...-identifies discrete genetic differences among
individuals that play a critical role in drug response
pharmacoepidemiology - ....ANSWER ...-study of the use and effects of drugs on
large groups of people
if give a drug and HR goes down to 40 this is an example of - ....ANSWER ...-
pharmacodynamic effect
if give a drug and liver metabolizes 80% of it this is an example of -
....ANSWER ...-pharmacokinetic effect
receptor theory - ....ANSWER ...-pharmacodynamics
- dug receptor is macromolecular complex which acts as site of action for a drug
- are usually proteins involved in production of normal cellular function
- ex. lock and key --> stereospecificity --> must have right shape and size for ligand to fit
in receptor
cant have a receptor without an - ....ANSWER ...-endogenous chemical
receptors are normally made up of - ....ANSWER ...-proteins
Ligand - ....ANSWER ...-chemical substances that bind to specific receptor
2 types of ligands - ....ANSWER ...-1) agonist
....FOR STUDY PURPOSES...©️2025 ALL RIGHTS RESERVED... 2
, 2) antagonist
agonist - ....ANSWER ...-bind to a receptor and Stimulate the function that
receptor serves
- mimics action of endogenous ligand (such as hormone or neurotransmitter) that binds
to same receptor
antagonist - ....ANSWER ...-bind to a receptor and block the function that receptor
serves
- has affinity for receptor but no efficacy
competitive binding - ....ANSWER ...-reversible (most drugs)
- ex: morphine vs narcan
noncompetitive binding - ....ANSWER ...-nonreversible
- ex: aspirin
allosteric agonist (activators) - ....ANSWER ...-enhance signal, respectively, by
binding to allosteric sites that influence signal transmission
-binds to one site but works somewhere else
allosteric antagonist - ....ANSWER ...-blocks signal, respectively, by binding to
allosteric sites that influence signal transmission
ED50 - ....ANSWER ...-Effective dose in 50% of population
TD50 - ....ANSWER ...-Toxic dose in 50% of population
LD50 - ....ANSWER ...-Lethal dose in 50% of population
....FOR STUDY PURPOSES...©️2025 ALL RIGHTS RESERVED... 3
