NSG 533 Exam 2 2025 Questions and Answers

NSG 533 Exam 2 2025 Questions and
Answers


genetics - ....ANSWER ...-study of inherited traits and their variation (individual)


genome - ....ANSWER ...-total genetic composition of an organism or species

(group)


genomics - ....ANSWER ...-molecular analysis of the entire genome of a species


gene - ....ANSWER ...-basic unit of heredity


list the four types of mendelian inheritance - ....ANSWER ...-1. autosomal

dominant

2. autosomal recessive

3. X-linked dominant

4. X-linked recessive


autosomal dominant - ....ANSWER ...-- phenotype is expressed in those who have

1 copy of a gene mutation




- mothers and fathers are equally likely to transmit or inherit the disorder




…FOR STUDENTS ONLY…©️2025 ALL RIGHTS RESERVED… 1

,- seen in multiple generations


autosomal recessive - ....ANSWER ...-- requires presence of 2 copies of a gene

mutation in order to express phenotype




- usually seen in a single generation




- mothers/fathers equally likely to transmit or inherit disorder


X-linked dominant - ....ANSWER ...-- dominant disorder caused by a mutation in a

gene on the X chromosome




- heterozygous female (XAXa) and hemizygous male (XAY)




- affected males have more severe phenotype


X-Linked Recessive - ....ANSWER ...-mutation on gene in X chromosome causes

phenotype to be expressed in hemizygous males (XaY) and homozygous females (XaXa)


types of X-linked recessive disorders - ....ANSWER ...-1. duchene muscular

dystrophy

2. hemophilia

3. color blindness


examples of X-Linked dominant disorders - ....ANSWER ...-1. Fragile X syndrome




…FOR STUDENTS ONLY…©️2025 ALL RIGHTS RESERVED… 2

, 2. Rett syndrome


examples of Autosomal Dominant disorders - ....ANSWER ...--Marfan syndrome


-Huntington disease


examples of Autosomal Recessive disorders - ....ANSWER ...-- cystic fibrosis


- sickle cell anemia

- PKU

- Tay-Sachs


types of genetic inheritance - ....ANSWER ...-1. mendelian inheritance


2. non-mendelian inheritance


types of non-mendelian inheritance - ....ANSWER ...-1. mitochondrial inheritance


2. genomic imprinting

3. uniparental disomy


mitochondrial inheritance - ....ANSWER ...-only females will transmit disease to

their offspring




- the ova contains mitochondria, sperm does not


genomic imprinting - ....ANSWER ...-- gene from mother or father may be

imprinted (silenced)




- if allele from mother is imprinted, only allele from father will be expressed


…FOR STUDENTS ONLY…©️2025 ALL RIGHTS RESERVED… 3