ONS ONCC CHEMOTHERAPY IMMUNOTHERAPY
Certificate Exam Questions with 100% Correct Answers
Latest Versions 2025 Graded A+
Common platinum-based agents: - ANSWER-
Cisplatin (Platinol)
Carboplatin (Paraplatin)
What is unique about nitrosoureas agents? -
ANSWER-Able to cross the blood-brain barrier;
can be effective in treating some brain tumors
Common nitrosoureas agents: - ANSWER-
Carmustine (BiCNU)
Lomustine (CeeNu)
Streptozocin (Zanosar)
Hypersensitivity can occur with late doses of: -
ANSWER-Carboplatin
These agents are typically categorized as highly
emetogenic: - ANSWER-1. Alkylating agents
,2. Nitrosoureas
Pre-administration labs for alkylating agents
and nitrosoureas: - ANSWER-BUN
Creatinine
CBC w/ diff
What is the medication Mesna used for? -
ANSWER-Bladder protectant with
administration of cyclophosphamide or
ifosfamide
Instruct pts receiving to avoid exposure
to cold air and consuming cold fluids for 3-4
days following treatment - ANSWER-Oxaliplatin
How do antimetabolites function? - ANSWER-
By blocking DNA and RNA growth by
interfering with enzymes needed for normal cell
metabolism
,Antimetabolites work in the phase. -
ANSWER-S
What types of cells are best affected by
antimetabolites? - ANSWER-Cells with high
division rates
Common side effects of antimetabolites: -
ANSWER-Myelosuppression
GI toxicities
Photosensitivity
Hand-foot syndrome
Common antimetabolite drugs: - ANSWER-
Azacitidine
Capecitabine
5-FU
Cytarabine
Decitabine
, Methotrexate
The institute for Safe Medication Practices
recommends what route of administration for
vincristine? - ANSWER-IV piggyback via gravity
Anthracycline antitumor abx work by: -
ANSWER-Interfering with enzymes necessary
for DNA to replicate in ALL phases of the cell
cycle
The two major classifications of antitumor
antibiotics are: - ANSWER-Anthracyclines
Non-anthracyclines
Common anthracycline antitumor abx: -
ANSWER-Daunorubicin
Doxorubicin
Epirubicin
Idarubicin
Certificate Exam Questions with 100% Correct Answers
Latest Versions 2025 Graded A+
Common platinum-based agents: - ANSWER-
Cisplatin (Platinol)
Carboplatin (Paraplatin)
What is unique about nitrosoureas agents? -
ANSWER-Able to cross the blood-brain barrier;
can be effective in treating some brain tumors
Common nitrosoureas agents: - ANSWER-
Carmustine (BiCNU)
Lomustine (CeeNu)
Streptozocin (Zanosar)
Hypersensitivity can occur with late doses of: -
ANSWER-Carboplatin
These agents are typically categorized as highly
emetogenic: - ANSWER-1. Alkylating agents
,2. Nitrosoureas
Pre-administration labs for alkylating agents
and nitrosoureas: - ANSWER-BUN
Creatinine
CBC w/ diff
What is the medication Mesna used for? -
ANSWER-Bladder protectant with
administration of cyclophosphamide or
ifosfamide
Instruct pts receiving to avoid exposure
to cold air and consuming cold fluids for 3-4
days following treatment - ANSWER-Oxaliplatin
How do antimetabolites function? - ANSWER-
By blocking DNA and RNA growth by
interfering with enzymes needed for normal cell
metabolism
,Antimetabolites work in the phase. -
ANSWER-S
What types of cells are best affected by
antimetabolites? - ANSWER-Cells with high
division rates
Common side effects of antimetabolites: -
ANSWER-Myelosuppression
GI toxicities
Photosensitivity
Hand-foot syndrome
Common antimetabolite drugs: - ANSWER-
Azacitidine
Capecitabine
5-FU
Cytarabine
Decitabine
, Methotrexate
The institute for Safe Medication Practices
recommends what route of administration for
vincristine? - ANSWER-IV piggyback via gravity
Anthracycline antitumor abx work by: -
ANSWER-Interfering with enzymes necessary
for DNA to replicate in ALL phases of the cell
cycle
The two major classifications of antitumor
antibiotics are: - ANSWER-Anthracyclines
Non-anthracyclines
Common anthracycline antitumor abx: -
ANSWER-Daunorubicin
Doxorubicin
Epirubicin
Idarubicin
