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Pediatric Pharmacology

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Pediatric pharmacology focuses on the study of drugs and their effects in children. It involves age-specific dosing to account for differences in metabolism and development. Medications are carefully chosen for pediatric safety to minimize adverse effects and ensure effectiveness. Pharmacokinetics (absorption, distribution, metabolism, and elimination) in children varies, making dosing adjustments necessary

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Institution
Advance Nursing
Course
Advance nursing

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Pediatric Pharmacology
Example of a high-potency steroid - Clobetasol



Example of combination therapy for acne - Retinoid + benzoyl peroxide + topical abx (e.g.,
Benzaclin)



Examples of low-potency topical steroids - Hydrocortisone 1-2.5%, Desonide



First line for purulent skin infection: - clindamycin or bactrim (MRSA concern if purulent).



First-line antibiotic for AOM - Amoxicillin



First-line for acne - Topical retinoid



First-line treatment for ADHD - Stimulants



First-line treatment for chlamydia in adolescents - Doxycycline



First-line treatment for pediatric UTI - Cephalexin



First-line treatment for preseptal cellulitis with sinusitis features - Augmentin



First-line treatments for pediatric constipation - MiraLAX, hydration, diet changes, senna,
behavioral interventions



How ibuprofen should be taken - With food, not more than every 6-8 hours

, Impetigo; cephalexin - What is this? (bonus: how do we treat it?)




ABX class for AOM with penicillin allergy - 3rd gen cephalosporin



Alternatives if amoxicillin fails or is contraindicated - Augmentin → 3rd-gen cephalosporins
(cefpodoxime, cefdinir) → clindamycin (if penicillin allergy)



Antibiotic duration for acute otitis media (AOM) in children under 2 years old - 10 days



Antibiotic good for skin infections and impetigo - Cephalexin



Antibiotic of choice for animal bites - Augmentin



Azithromycin use in children - Atypical pneumonia, pertussis, strep (if PCN allergy), chlamydia (if
doxy not appropriate)



Bactrim cautions - avoid <2 months due to hyperbilirubinemia; risk of Stevens-Johnson
syndrome (SJS)



Benefit of second-generation antihistamines - Less sedating than first-generation



Cautions when using ibuprofen in children - GERD, ulcers, kidney problems, platelet issues (e.g.,
leukemia)



Dosing of elemental iron for iron-deficiency anemia (IDA) in children - 3-6 mg/kg/day

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Institution
Advance nursing
Course
Advance nursing

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June 22, 2025
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Written in
2024/2025
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