NURS 5220/ NURS5220 EXAM 3 |
COMPLETE 2025 ACTUAL EXAM WITH CORRECT
VERIFIED ANSWERS | GUARANTEED A+ EXAM
EXCELLENCE
What is ACHE? - ✔✔✔ Correct Answer > Acetylcholine esterase is an
enzyme that metabolizes ACh.
What are the active metabolites of benzodiazepines? - ✔✔✔ Correct
Answer > Diazepam (with a half-life exceeding 100 hours) and
midazolam (rapidly metabolized to an α-hydroxylated compound with
biologic activity).
What effect do high doses of benzodiazepines have on CMR02 & CBF? -
✔✔✔ Correct Answer > They reduce CMR02 & CBF.
,What are the adverse effects of midazolam? - ✔✔✔ Correct Answer >
Prolonged sedation, impaired cognition and psychomotor
performance, unwanted amnesia, potential for delirium, increased
risk of accidents and falls, dependence and withdrawal effects
What effect do benzodiazepines have on the threshold to local
anesthetic-induced seizures? - ✔✔✔ Correct Answer > They increase
the threshold to local anesthetic-induced seizures.
Which benzodiazepines have no active metabolites? - ✔✔✔ Correct
Answer > Oxazepam, lorazepam, and temazepam.
What factors can alter the metabolism of benzodiazepines? - ✔✔✔
Correct Answer > Disease and age.
,What is the duration of action of benzodiazepines primarily determined
n n n n n n n n n
by? - ✔✔✔ Correct Answer > The α phase (distribution-redistribution
n n n n n n n n n n
n from CNS) dynamics rather than the rate of elimination.
n n n n n n n n
What are the pharmacodynamic effects of benzodiazepines on the
n n n n n n n n
CNS? - ✔✔✔ Correct Answer > CNS depressant effects including
n n n n n n n n n n
n anxiolysis, sedation, sleep, anticonvulsant, amnesia, muscle
n n n n n
n relaxation, and inhibition of alcohol withdrawal symptoms.
n n n n n n
What is the dose-related effect of benzodiazepines on anterograde
n n n n n n n n
amnesia? - ✔✔✔ Correct Answer > They cause anterograde amnesia
n n n n n n n n n n
n at high doses.
n n
What are the potential drawbacks of benzodiazepine use? - ✔✔✔
n n n n n n n n n
Correct Answer > Awareness regarding addiction, withdrawal,
n n n n n n
, recreational abuse, and the development of other drug classes has led
n n n n n n n n n n
n to a decline in their use.
n n n n n
Which CYP enzyme is primarily responsible for the metabolism of
n n n n n n n n n
benzodiazepines? - ✔✔✔ Correct Answer > CYP3A4.
n n n n n n n
Which benzodiazepine has a half-life exceeding 100 hours? - ✔✔✔
n n n n n n n n n
Correct Answer > Diazepam.
n n n
Which benzodiazepine is rapidly metabolized to an α-hydroxylated
n n n n n n n
compound with biologic activity? - ✔✔✔ Correct Answer > Midazolam.
n n n n n n n n n n
Which benzodiazepines have no active metabolites? - ✔✔✔ Correct
n n n n n n n n
n Answer > Oxazepam, lorazepam, and temazepam.
n n n n n
COMPLETE 2025 ACTUAL EXAM WITH CORRECT
VERIFIED ANSWERS | GUARANTEED A+ EXAM
EXCELLENCE
What is ACHE? - ✔✔✔ Correct Answer > Acetylcholine esterase is an
enzyme that metabolizes ACh.
What are the active metabolites of benzodiazepines? - ✔✔✔ Correct
Answer > Diazepam (with a half-life exceeding 100 hours) and
midazolam (rapidly metabolized to an α-hydroxylated compound with
biologic activity).
What effect do high doses of benzodiazepines have on CMR02 & CBF? -
✔✔✔ Correct Answer > They reduce CMR02 & CBF.
,What are the adverse effects of midazolam? - ✔✔✔ Correct Answer >
Prolonged sedation, impaired cognition and psychomotor
performance, unwanted amnesia, potential for delirium, increased
risk of accidents and falls, dependence and withdrawal effects
What effect do benzodiazepines have on the threshold to local
anesthetic-induced seizures? - ✔✔✔ Correct Answer > They increase
the threshold to local anesthetic-induced seizures.
Which benzodiazepines have no active metabolites? - ✔✔✔ Correct
Answer > Oxazepam, lorazepam, and temazepam.
What factors can alter the metabolism of benzodiazepines? - ✔✔✔
Correct Answer > Disease and age.
,What is the duration of action of benzodiazepines primarily determined
n n n n n n n n n
by? - ✔✔✔ Correct Answer > The α phase (distribution-redistribution
n n n n n n n n n n
n from CNS) dynamics rather than the rate of elimination.
n n n n n n n n
What are the pharmacodynamic effects of benzodiazepines on the
n n n n n n n n
CNS? - ✔✔✔ Correct Answer > CNS depressant effects including
n n n n n n n n n n
n anxiolysis, sedation, sleep, anticonvulsant, amnesia, muscle
n n n n n
n relaxation, and inhibition of alcohol withdrawal symptoms.
n n n n n n
What is the dose-related effect of benzodiazepines on anterograde
n n n n n n n n
amnesia? - ✔✔✔ Correct Answer > They cause anterograde amnesia
n n n n n n n n n n
n at high doses.
n n
What are the potential drawbacks of benzodiazepine use? - ✔✔✔
n n n n n n n n n
Correct Answer > Awareness regarding addiction, withdrawal,
n n n n n n
, recreational abuse, and the development of other drug classes has led
n n n n n n n n n n
n to a decline in their use.
n n n n n
Which CYP enzyme is primarily responsible for the metabolism of
n n n n n n n n n
benzodiazepines? - ✔✔✔ Correct Answer > CYP3A4.
n n n n n n n
Which benzodiazepine has a half-life exceeding 100 hours? - ✔✔✔
n n n n n n n n n
Correct Answer > Diazepam.
n n n
Which benzodiazepine is rapidly metabolized to an α-hydroxylated
n n n n n n n
compound with biologic activity? - ✔✔✔ Correct Answer > Midazolam.
n n n n n n n n n n
Which benzodiazepines have no active metabolites? - ✔✔✔ Correct
n n n n n n n n
n Answer > Oxazepam, lorazepam, and temazepam.
n n n n n
