GU, WOMENS HEALTH Questions with
complete solution 2025
Which of the following would be the least likely candidate for weight loss
surgery?
A. A 43-year-old man with BMI of 42 kg/m2
B. A 38-year-old with BMI 37 kg/m2 and type 2 diabetes mellitus
C. A 29-year-old with BMI of 35 kg/m2 and who has been unable to sustain
healthy weight loss with multiple prior weight loss efforts
D. A 24-year-old with BMI of 31 kg/m2 who does not believe current weight is
of concern - correct answer ✔D. A 24-year-old with BMI of 31 kg/m2 who
does not believe current weight is of concern
ideal candidates for weight loss surgery include those with a BMI=40 kg/m2 or
over 100 pounds overweight, those with a BMI=35 kg/m2 and with at least one
obesity-related comorbidity (such as type 2 diabetes, hypertension, sleep
apnea, heart disease, etc.), or individuals who have been unable to achieve a
healthy weight loss for sustained periods of time with prior weight loss efforts.
**A 66-year-old woman being managed for Addison's disease presents for
follow-up evaluation. Findings consistent with an excessive dose of the
medication taken for this condition would include:
A. Diffuse hyperpigmentation.
B. Blood pressure of 168/98 mm Hg.
C. Loss of axillary hair.
,D. A white blood cell count of 6,000/mm3. - correct answer ✔B. Blood
pressure of 168/98 mm Hg.
The first-line medication for Addison's disease is the use of a systemic
corticosteroid such as oral prednisone; the goal is to replace endogenous
cortisol in a manner that is consistent with the normal, physiologic diurnal
variation. A typical starting dose is 15 mg q AM and 10 mg q PM. If the dose
of prednisone is too high for this patient, she can demonstrate signs and
symptoms of hypercortisolism, such as hypertension.
Mrs. Jansen is a 61-year-old patient who has difficult-to-manage type 2
diabetes mellitus. After trials of several oral and injectable medication
combinations including insulin releasers, with adherence, her A1c remained
significantly above goal. Three months ago, the nurse practitioner adjusted
Mrs. Jansen's regimen to include basal and mealtime insulin and advised the
continuation of metformin. Today Mrs. Jansen's A1c is 6.8%. The appropriate
response is to:
A. Increase the insulin by 20%.
B. Consider discontinuing metformin.
C. Continue the present regimen.
D. Repeat the A1c in one month. - correct answer ✔C. Continue the present
regimen.
therapeutic goal of management as an A1c of <7%. At 6.8%, Mrs. Jansen has
attained the therapeutic goal, and the appropriate response is to continue her
present regimen.
A 49-year-old female of European ancestry with type 2 diabetes mellitus was
started on lisinopril 20 mg tablet daily 6 weeks ago for the management of
hypertension. Today her blood pressure is 128/78 mm Hg and the patient is
feeling well. The appropriate action at this time would be to:
,A. Order a white blood cell count to assess for neutropenia.
B. Continue on her current medication regimen.
C. Add oral HCTZ 12.5 mg to enhance HTN control.
D. Assess renal function. - correct answer ✔B. Continue on her current
medication regimen.
Lisinopril, an angiotensin-converting enzyme inhibitor, is the appropriate class
of medication in the patient with diabetes and comorbid hypertension
according to the Joint National Committee 8 (JNC-8) report. Given her age
and DM, her blood pressure goal is <140/90 mm Hg. She also meets the
blood pressure goal per ACC/AHA guidelines that recommend <130/80 mm
Hg for those with type 2 diabetes mellitus.
Which of the following describes, in part, metformin's mechanism of action?
A. Reduces insulin resistance
B. Facilitates renal glucose excretion
C. Stimulates insulin production
D. Inactivates incretin - correct answer ✔A. Reduces insulin resistance
Metformin has a multimodal mechanism of action that includes (1)
sensitization of peripheral insulin receptors and (2) decreasing the rate of
hepatic gluconeogenesis.
When developing a management plan for a 58-year-old man with a 20-year
history of type 2 diabetes mellitus, you recognize that which of the following
oral medications is less likely to be effective in controlling plasma glucose
because of his long-standing condition?
, A. Metformin
B. Canagliflozin
C. Glipizide
D. Pioglitazone - correct answer ✔C. Glipizide
After several years of supraphysiologic production, the beta cells eventually
"burn out" and cannot produce significant amounts of insulin release. An
insulin releaser, such as glipizide, will not be effective and exogenous insulin
must be added to the regimen.
Which of the following is consistent with the diagnosis of diabetes mellitus?
A. Fasting plasma glucose=100-125 mg/dL (5.6-6.9 mmol/L)
B. A1c >6.5%
C. Plasma glucose=140-199 mg/dL (7.8-11.0 mmol/L) on the 75-g oral
glucose tolerance test
D. Random plasma glucose >125 mg/dL without classic diabetes mellitus
symptoms - correct answer ✔B. A1c >6.5%
Diagnostic criteria for diabetes mellitus include
(1) fasting plasma glucose >126 mg/dL on two occasions,
(2) A1c >6.5%,
(3) plasma glucose tolerance >200 mg/dL 2 hours after a 75-g glucose load,
or
(4) a random plasma glucose >200 mg/dL along with classic symptoms of
polyuria, polydipsia, or polyphagia along with unexplained weight loss or
hyperglycemic crisis.