Official summer 2024 Pearson Edexcel 8BS0/02 GCE AS Level In Business
(8BS0) Paper 02 Managing Business Activities Merged Question Paper +
Mark Scheme
Investigator A has biological specimens that are coded and linked to identifiers of the source
individuals. Investigator A provides the specimens to Investigator B but does not provide the
individual identifiers. Investigator B agrees not to re-identify the source individuals. Is
Investigator B's research using the biospecimens human subjects research according to the
definition of human subjects research in the federal regulations? Correct Answer No,
because Investigator B cannot readily ascertain the identity of the source individual and
Investigator B has agreed not to attempt re-identification.
Identify which types of discrimination the Genetic Information Non-Discrimination Act
(GINA) protects individuals from: Correct Answer Health insurance and employment
discrimination
Investigator A conducts research on emphysema using biospecimens from human subjects.
The consent form indicates that the research will focus exclusively on emphysema.
Investigator B wishes to use the biospecimens for research on lung cancer. Can Investigator
B use the specimens for cancer research without re-consent if the specimens are de-
identified? Correct Answer Yes, if the biospecimens are de-identified then the research
is no longer considered human subjects research.
Under which of the following conditions is it appropriate to re-contact the individuals who
provided biological specimens? Correct Answer Original signed consent documents
include provisions for recontacting subjects
Which choice is the best definition of "genetic determinism?" Correct Answer Genes are
primarily responsible for human traits, including health, behavior, and disease
Which choice best describes the purpose of most pharmacogenomic research? Correct
Answer To evaluate the association between individual genotypes and the safety and
efficacy of a particular drug or class of drugs
When conducting research that involves collecting biological specimens for genetic testing,
which of the following issues is the most important for the IRB to consider? Correct
Answer Effects of findings on other family members
(8BS0) Paper 02 Managing Business Activities Merged Question Paper +
Mark Scheme
Investigator A has biological specimens that are coded and linked to identifiers of the source
individuals. Investigator A provides the specimens to Investigator B but does not provide the
individual identifiers. Investigator B agrees not to re-identify the source individuals. Is
Investigator B's research using the biospecimens human subjects research according to the
definition of human subjects research in the federal regulations? Correct Answer No,
because Investigator B cannot readily ascertain the identity of the source individual and
Investigator B has agreed not to attempt re-identification.
Identify which types of discrimination the Genetic Information Non-Discrimination Act
(GINA) protects individuals from: Correct Answer Health insurance and employment
discrimination
Investigator A conducts research on emphysema using biospecimens from human subjects.
The consent form indicates that the research will focus exclusively on emphysema.
Investigator B wishes to use the biospecimens for research on lung cancer. Can Investigator
B use the specimens for cancer research without re-consent if the specimens are de-
identified? Correct Answer Yes, if the biospecimens are de-identified then the research
is no longer considered human subjects research.
Under which of the following conditions is it appropriate to re-contact the individuals who
provided biological specimens? Correct Answer Original signed consent documents
include provisions for recontacting subjects
Which choice is the best definition of "genetic determinism?" Correct Answer Genes are
primarily responsible for human traits, including health, behavior, and disease
Which choice best describes the purpose of most pharmacogenomic research? Correct
Answer To evaluate the association between individual genotypes and the safety and
efficacy of a particular drug or class of drugs
When conducting research that involves collecting biological specimens for genetic testing,
which of the following issues is the most important for the IRB to consider? Correct
Answer Effects of findings on other family members
