TEST BANK FOR : Pharmacology: A Patient-Centered Nursing Process Approach 11th Edition legal and basic principles Questions with v erified Answers

, Pharm Test 1 (Chap 1-11)
Questions With Verified Answers

,The nurse is obtaining consent from a subject newly recruited for a clinical drug trial that will last for 6
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months. All subjects will be given gift certificates for participating. One subject says, "Well, I guess if the
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drug doesn't work, I'll just have to put up with the symptoms for 6 months." What will the nurse tell the
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subject?
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a. "Participation for the duration of the study is required."
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b. "Participation may end at any time without penalty."
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c. "Withdrawal from the study may end at any time, but the gift certificate will not be given."
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d. "You can request placement in the treatment group." << ANS>>"Participation may end at any time
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without penalty."
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The nurse is assisting with a clinical drug trial in which the side effects of two effective drugs are being
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compared. A patient who would benefit from either drug has elected to withdraw from the study, and
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the nurse assists with the paperwork to facilitate this. This is an example of
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a. autonomy.
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b. beneficence.
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c. justice.
b b




d. veracity << ANS>>autonomy
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During a clinical drug trial for a new medication, researchers note a previously unknown serious adverse
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effect occurring in more than 50% of subjects. The study is discontinued. Which ethical principle is being
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exercised?
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a. Beneficence
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b. Justice
b b




c. Respect for persons
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d. Veracity << ANS>>Beneficence
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In a 5-year experimental clinical trial to investigate a new cancer treatment, researchers in the second
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byear note overwhelming improvement in almost all of the subjects in the treatment group. The lead
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bresearcher elects to continue the study. Which ethical principle is being violated?
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a. Beneficence
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b. Justice
b b

, c. Respect for persons
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d. Veracity << ANS>>Justice
b b b




The nurse is enrolling subjects for a double-blind experimental study. One patient asks the nurse to
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explain the role of the experimental group. The nurse will explain that subjects in the experimental
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group in this type of study
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a. are selected for participation in that group.
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b. have unique baseline characteristics.
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c. receive a placebo.
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d. receive the treatment being evaluated. << ANS>>receive the treatment being evaluated
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The nurse is obtaining signatures on consent forms for participation in a clinical drug trial. One patient
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says, "I'm not sure I want to do this, but I need the cash." The nurse will take which action?
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a. Ask the patient to clarify concerns.
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b. Reinforce that cash is given to all subjects equally.
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c. Report this statement to the party named on the consent.
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d. Review the elements of the study and obtain consent. << ANS>>Report this statement to the party
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named on the consent
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Which is the characteristic of preclinical in vivo testing?
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a. A comparison of experimental and control data in animals
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b. A study conducted in a test tube in a laboratory
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c. A study that determines the effects of the placebo in human participants
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d. A study to assess the seriousness of the disease to be treated << ANS>>A comparison of experimental
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and control data in animals
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Many drugs marketed in the 1980s may not be effective in a majority of the population. The nurse
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understands that this is because these drugs
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a. did not pass through the appropriate phases of clinical trials.
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b. did not require human subject protections and are invalid.
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c. were not tested on women, minorities, or children.
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d. were tested on healthy subjects only. << ANS>>were not tested on women, minorities, or children.
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The nurse is assisting with data collection in a study of drug effects in healthy subjects. The nurse assists
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with blood and urine collection to determine serum drug levels and the presence of metabolites in the
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urine. Which phase of a drug study does this represent?
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a. Phase I
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