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Exam (elaborations)

IRB Training – 2025/2026 – Ethical Guidelines, Vulnerable Populations, and Compliance Requirements for Human Research

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This document offers a comprehensive IRB (Institutional Review Board) training exam guide for the 2025/2026 academic year, focusing on the ethical conduct of research involving human subjects. It covers key principles like respect for persons, beneficence, and justice, and includes detailed definitions and scenarios involving vulnerable populations, informed consent, coercion, undue influence, inducements, and risk-benefit analysis. Also covered are IRB structure, federal regulations, and subpart protections for groups such as children, prisoners, and pregnant women.

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Uploaded on
June 16, 2025
Number of pages
14
Written in
2024/2025
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IRB Training 2025/2026 Exam Questions
and Answers | A+ Score Assured



Vulnerable subjects - 🧠 ANSWER ✔✔persons who "have difficulty providing

voluntary, informed consent arising from limitations in decision-making

capacity ... or situational circumstances ..., or because they are especially

at risk for exploitation."

What is the first question when thinking about conducting research on

vulnerable subjects? - 🧠 ANSWER ✔✔To ask whether the research could

include a less vulnerable population instead, and still answer the research

question


Vulnerable Populations - 🧠 ANSWER ✔✔pregnant women, human fetuses,

neonates, prisoners, children, individuals with physical disabilities,

individuals with mental disabilities or cognitive impairments, economically

disadvantaged, socially disadvantaged, terminally ill or very sick, racial or

ethnic minorities, institutionalized persons (correctional facilities, nursing

homes, mental health facilities)


COPYRIGHT©NINJANERD 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER:
619652435. TERMS OF USE. PRIVACY STATEMENT. ALL RIGHTS RESERVED 1

, Physical control - 🧠 ANSWER ✔✔subjects who are physically forced to

participate in research


Coercion - 🧠 ANSWER ✔✔The use of a credible threat of harm or force to

control another person


Undue influence - 🧠 ANSWER ✔✔The misuse of a position of confidence or

power to lead or influence others to make a decision they would not

otherwise make


Manipulation - 🧠 ANSWER ✔✔The deliberate design and management of

conditions or information intended to lead subjects to make decision they

would not otherwise make (lying, withholding information, exaggerating)


Exploitation - 🧠 ANSWER ✔✔the action of treating someone unfairly in

order to benefit from them in some way


What does vulnerability arise from? - 🧠 ANSWER ✔✔Intrinsic factors,

characteristics, or attributes of the individual


Capacity-related cognitive vulnerability - 🧠 ANSWER ✔✔subjects to some

extent lack capacity to make informed choices




COPYRIGHT©NINJANERD 2025/2026. YEAR PUBLISHED 2025. COMPANY REGISTRATION NUMBER:
619652435. TERMS OF USE. PRIVACY STATEMENT. ALL RIGHTS RESERVED 2

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