AG-ACNP Board Certification exam
2025 Questions and Answers
TIBC - ....ANSWER☑️☑️...-total iron binding capacity
normal - 250-450
Higher iron binding capacity need mean GREATER need for iron
MCV - ....ANSWER☑️☑️...-Mean corpuscular volume-average volume or size of a
single red blood cell
Normal: 80-100
<80 - microcytic
80-100 - normocytic
>100 - macrocytic
MCHC - ....ANSWER☑️☑️...-Mean Corpuscular Hgb Concentration
Normal: 32-36%
< 32% - Hypochromic
32-36% - normochromic
> 36% - hyperchromic
Low MCV diseases - ....ANSWER☑️☑️...-Iron deficiency anemia
Thalassemia
High MCV diseases - ....ANSWER☑️☑️...-B12 or Folate deficiency
ETOH
FOR STUDY PURPOSES ONLY ©️ 2025 ALL RIGHTS RESERVED 1
,Liver failure
Drug effects
Normocyctic anemia diseases - ....ANSWER☑️☑️...-Anemia of chronic diseases
sickle cell
renal failure
blood loss
hemolysis
iron deficiency anemia - ....ANSWER☑️☑️...-slow onset, few sx w/ Hct > 30
Low serum ferritin
High TIBC
High RDW (red cell distribution width)
Positive Brudzinski's sign - ....ANSWER☑️☑️...-is flexion of the hips and knees
when the neck is flexed
Likely meningitis!
Syphilis - ....ANSWER☑️☑️...-4 stages
Dx: VDRL or RPR --> then confirm with TP-PA or FTA-ABS (treponemal test)
Tx: Penicillin G, if allergic --> Doxy or Tetra
pulseless ventricular tachycardia (VT) defibrillation - ....ANSWER☑️☑️...-150-200 J
on biphasic and 360 J on a monophasic defibrillator
cerebral perfusion pressure (CPP) calc? - ....ANSWER☑️☑️...-MAP - ICP
Normal: 60-80
acute muscle strain Tx - ....ANSWER☑️☑️...-NSAIDS
FOR STUDY PURPOSES ONLY ©️ 2025 ALL RIGHTS RESERVED 2
, Cyclobenzaprine (muscle relaxant)
Acute anal fissures tx - ....ANSWER☑️☑️...-sitz baths, stool softeners, and topical
corticosteroids
Chronic anal fissures tx - ....ANSWER☑️☑️...-topical nitroglycerin or botulinum toxin
injections
Meningitis - ....ANSWER☑️☑️...-Acute bacterial meningitis --> medical emergency
Pathogens: Strep pneumoniae, Hemophilus influenzae, Neisseria meningitidis
Sx: Fever, severe HA, n/v, NUCHAL RIGIDITY (stiff neck), photophobia
Positive Kernig's sign: pain and spasms of hamstirng muscles
Positive Brudzinki's sign
Dx: LP --> CSF cloudy or xanthocrhomic (yellow)
Elevated protein & decreased GLU --> Bacterial!
CT head if indicated
Tx: Dexamethasone (steroid) before Abx
Abx: Ampicillin + Vancomycin + Ceftriaxone
Cushing's Syndrome - ....ANSWER☑️☑️...-hypersectrion of ACTH from pituitary
Sx: Moon face, central obesity, HTN
Labs: HyperGLU, HyperNa, HypoK, Metabolic alkalosis
Tests: Dexamethasone suppression test
Tx: Exogenous: d/c meds; Endogenous: resection of pituitary gland
Benzo OD signs - ....ANSWER☑️☑️...-central nervous system depression with
normal or near-normal vital signs
FOR STUDY PURPOSES ONLY ©️ 2025 ALL RIGHTS RESERVED 3
2025 Questions and Answers
TIBC - ....ANSWER☑️☑️...-total iron binding capacity
normal - 250-450
Higher iron binding capacity need mean GREATER need for iron
MCV - ....ANSWER☑️☑️...-Mean corpuscular volume-average volume or size of a
single red blood cell
Normal: 80-100
<80 - microcytic
80-100 - normocytic
>100 - macrocytic
MCHC - ....ANSWER☑️☑️...-Mean Corpuscular Hgb Concentration
Normal: 32-36%
< 32% - Hypochromic
32-36% - normochromic
> 36% - hyperchromic
Low MCV diseases - ....ANSWER☑️☑️...-Iron deficiency anemia
Thalassemia
High MCV diseases - ....ANSWER☑️☑️...-B12 or Folate deficiency
ETOH
FOR STUDY PURPOSES ONLY ©️ 2025 ALL RIGHTS RESERVED 1
,Liver failure
Drug effects
Normocyctic anemia diseases - ....ANSWER☑️☑️...-Anemia of chronic diseases
sickle cell
renal failure
blood loss
hemolysis
iron deficiency anemia - ....ANSWER☑️☑️...-slow onset, few sx w/ Hct > 30
Low serum ferritin
High TIBC
High RDW (red cell distribution width)
Positive Brudzinski's sign - ....ANSWER☑️☑️...-is flexion of the hips and knees
when the neck is flexed
Likely meningitis!
Syphilis - ....ANSWER☑️☑️...-4 stages
Dx: VDRL or RPR --> then confirm with TP-PA or FTA-ABS (treponemal test)
Tx: Penicillin G, if allergic --> Doxy or Tetra
pulseless ventricular tachycardia (VT) defibrillation - ....ANSWER☑️☑️...-150-200 J
on biphasic and 360 J on a monophasic defibrillator
cerebral perfusion pressure (CPP) calc? - ....ANSWER☑️☑️...-MAP - ICP
Normal: 60-80
acute muscle strain Tx - ....ANSWER☑️☑️...-NSAIDS
FOR STUDY PURPOSES ONLY ©️ 2025 ALL RIGHTS RESERVED 2
, Cyclobenzaprine (muscle relaxant)
Acute anal fissures tx - ....ANSWER☑️☑️...-sitz baths, stool softeners, and topical
corticosteroids
Chronic anal fissures tx - ....ANSWER☑️☑️...-topical nitroglycerin or botulinum toxin
injections
Meningitis - ....ANSWER☑️☑️...-Acute bacterial meningitis --> medical emergency
Pathogens: Strep pneumoniae, Hemophilus influenzae, Neisseria meningitidis
Sx: Fever, severe HA, n/v, NUCHAL RIGIDITY (stiff neck), photophobia
Positive Kernig's sign: pain and spasms of hamstirng muscles
Positive Brudzinki's sign
Dx: LP --> CSF cloudy or xanthocrhomic (yellow)
Elevated protein & decreased GLU --> Bacterial!
CT head if indicated
Tx: Dexamethasone (steroid) before Abx
Abx: Ampicillin + Vancomycin + Ceftriaxone
Cushing's Syndrome - ....ANSWER☑️☑️...-hypersectrion of ACTH from pituitary
Sx: Moon face, central obesity, HTN
Labs: HyperGLU, HyperNa, HypoK, Metabolic alkalosis
Tests: Dexamethasone suppression test
Tx: Exogenous: d/c meds; Endogenous: resection of pituitary gland
Benzo OD signs - ....ANSWER☑️☑️...-central nervous system depression with
normal or near-normal vital signs
FOR STUDY PURPOSES ONLY ©️ 2025 ALL RIGHTS RESERVED 3
