When is a cancer patient most susceptible to increased risk for
infection, anemia and/or bleeding? - ✔️✔ Correct
Answer Answer: When the patient has low blood counts-
Myelosuppression
Nadir: Meaning low point,
Nadir is the point in time between chemotherapy cycles in which you
experience low blood counts.
What is Myelosuppression? - ✔️✔ Correct
Answer Myelosuppression is a condition in which bone marrow
activity is decreased, resulting in fewer red blood cells, white blood
cells, and platelets. It is a side effect of some cancer treatments.
Side effects that are common for patients taking cyclophosphamide
(Cytoxan): - ✔️✔ Correct Answer Low blood counts
,Nausea and vomiting: more common with larger doses, usually
beginning 6-10 hours after therapy.
Poor appetite
The following are less common side effects:
Diarrhea
Mouth sores
Tumor lysis syndrome can lead to _____________________failure - ✔
️✔ Correct Answer Tumor lysis syndrome can lead to kidney
failure and other sudden health problems within 24 - 48 hours of
therapy
People about to receive chemotherapy for a cancer with a high cell
turnover rate, especially lymphomas and leukemias, should receive
prophylactic oral or IV allopurinol as well as adequate IV hydration to
,maintain high urine output (> 2.5 L/day) to prevent which condition? -
✔️✔ Correct Answer Tumor lysis syndrome
WHAT changes in electrolytes and metabolites are expected in tumor
lysis syndrome ? - ✔️✔ Correct Answer Hyperkalemia
Hyperphosphatemia
LOW calcium (hypocalcemia),
High uric acid (hyperuricemia),
and higher than normal levels of blood urea nitrogen (BUN) and other
nitrogen-containing compounds (azotemia)
A cancer patient is unable to provide self-care. His disease is
progressing rapidly and prognosis is poor. Which number likely
represents his Karnofsky Performance Status?
A. 100
B. 70
, C. 40
D. 0 - ✔️✔ Correct Answer C. 40
Disabled; requires special care & assistance.
**************************************************
0 - DEAD
100 - no evidence of disease
A cancer patient is fully active and able to carry on all pre-disease
activities without restrictions. Which Eastern Cooperative Oncology
Group (ECOG) grade is appropriate?
A. Grade 0
B. Grade 1
C. Grade 2
D. Grade 3 - ✔️✔ Correct Answer A. Grade 0 is fully active and
able to carry on all pre-disease activities without restrictions.