Terms in this set (62)
Quiz____?
What is the study of physiochemical properties of drugs and how they influence the body
called?
A. Pharmaceutics
B. Pharmacokinetics
C. Pharmacodynamics
D. Pharmacotherapeutics -
Answer✓✓
ANS: C
Pharmacodynamics: The study of what the drug does to the body. The study of the biochemical
and physiologic interactions of drugs at their sites of activity. It examines the effect of the drug
on the body. (Lilley, 2020 p. 14)
Pharmacokinetics: The study of what the body does to the drug. The study of what happens to
a drug from the time it is put into the body until the parent drug and all metabolites have left
the body. Pharmacokinetics represent the drug absorption into, distribution and metabolism
within, and excretion from the body. (Lilley, 2020 p. 14)
1
, Pharmacotherapeutics: The treatment of pathologic conditions through the use of drugs. (Lilley,
2020 p. 14)
Pharmaceutics The science of preparing and dispensing drugs, including dosage form design.
(Lilley, 2020 p. 14) The study of how various drug forms influence the way in which the drug
affects the body. (Lilley, 2020 p. 16
Quiz____?
A patient asks the nurse the difference between a generic drug and a trade or brand-name drug.
Which of the following are true regarding generic drugs? (Select all that apply)
A.Have less potential for abuse and dependence
B.Have the same chemical composition as the brand-name drug
C.May have several brand names
D.May have several generic names
E.Are usually less expensive than a brand-name drug -
Answer✓✓
Answer: B, C, E
Generic and trade or brand-name drugs have the same chemical composition and the same
effects, Generic drugs are usually less expensive. Each drug has only one generic name. The
trade name is the brand of proprietary name given by the manufacturer; various manufacturers
give the drug different brand names. There is no difference in abuse potential between a generic
and brand-name drug.
2
, Quiz____?
Patients with renal failure would most likely have problems with which pharmacokinetic
process?
A.Excretion
B.Absorption
C.Metabolism
D.Distribution -
Answer✓✓
ANS: A
The kidneys are responsible for the majority of drug excretion. A patient with renal failure
would have a difficult time with drug excretion.
Quiz____?
A staff educator is preparing an in-service to review factors that influence medication
metabolism. Which of the following would the educator include as a reason to administer a
lower medication dosage? (Select all that apply)
A.Increased renal excretion
B.Increased medication-metabolizing enzymes
C.Liver failure
D.Peripheral vascular disease
E.Concurrent use of medication with the same pathway of metabolism -
3
, Answer✓✓
Answer: C, E
Rationale: Increased renal excretion and Increased medication-metabolizing enzymes decrease
the concentration of the medication, potentially requiring increased strength. Liver failure
decreases metabolism, thus increasing the concentration of a medication. This requires
decreasing the dosage. Peripheral vascular disease impairs distribution, may require an
increased dose. When the same pathway metabolizes two medications, they compete for
metabolism, potentially increasing the concentration of one or both medications. Requiring
deceasing the dose of one or both medications
Quiz____?
A patient asks the nurse why a lower dose of IV pain medication is being given than the
previous oral dose. What is the nurse's best response to the patient?
A."Medications given orally bypass the portal circulatory system."
B."Medications given intravenously are not affected by the first-pass effect."
C."Drugs administered intravenously enter the portal system before systemic distribution."
D."A large percentage of an intravenously administered drug is metabolized into inactive
metabolites in the liver." -
Answer✓✓
Ans: B
Rationale: When drugs with a high first-pass effect are administered orally, a large amount of
drug may be metabolized before it reaches the systemic circulation. The same drug given IV will
4
Quiz____?
What is the study of physiochemical properties of drugs and how they influence the body
called?
A. Pharmaceutics
B. Pharmacokinetics
C. Pharmacodynamics
D. Pharmacotherapeutics -
Answer✓✓
ANS: C
Pharmacodynamics: The study of what the drug does to the body. The study of the biochemical
and physiologic interactions of drugs at their sites of activity. It examines the effect of the drug
on the body. (Lilley, 2020 p. 14)
Pharmacokinetics: The study of what the body does to the drug. The study of what happens to
a drug from the time it is put into the body until the parent drug and all metabolites have left
the body. Pharmacokinetics represent the drug absorption into, distribution and metabolism
within, and excretion from the body. (Lilley, 2020 p. 14)
1
, Pharmacotherapeutics: The treatment of pathologic conditions through the use of drugs. (Lilley,
2020 p. 14)
Pharmaceutics The science of preparing and dispensing drugs, including dosage form design.
(Lilley, 2020 p. 14) The study of how various drug forms influence the way in which the drug
affects the body. (Lilley, 2020 p. 16
Quiz____?
A patient asks the nurse the difference between a generic drug and a trade or brand-name drug.
Which of the following are true regarding generic drugs? (Select all that apply)
A.Have less potential for abuse and dependence
B.Have the same chemical composition as the brand-name drug
C.May have several brand names
D.May have several generic names
E.Are usually less expensive than a brand-name drug -
Answer✓✓
Answer: B, C, E
Generic and trade or brand-name drugs have the same chemical composition and the same
effects, Generic drugs are usually less expensive. Each drug has only one generic name. The
trade name is the brand of proprietary name given by the manufacturer; various manufacturers
give the drug different brand names. There is no difference in abuse potential between a generic
and brand-name drug.
2
, Quiz____?
Patients with renal failure would most likely have problems with which pharmacokinetic
process?
A.Excretion
B.Absorption
C.Metabolism
D.Distribution -
Answer✓✓
ANS: A
The kidneys are responsible for the majority of drug excretion. A patient with renal failure
would have a difficult time with drug excretion.
Quiz____?
A staff educator is preparing an in-service to review factors that influence medication
metabolism. Which of the following would the educator include as a reason to administer a
lower medication dosage? (Select all that apply)
A.Increased renal excretion
B.Increased medication-metabolizing enzymes
C.Liver failure
D.Peripheral vascular disease
E.Concurrent use of medication with the same pathway of metabolism -
3
, Answer✓✓
Answer: C, E
Rationale: Increased renal excretion and Increased medication-metabolizing enzymes decrease
the concentration of the medication, potentially requiring increased strength. Liver failure
decreases metabolism, thus increasing the concentration of a medication. This requires
decreasing the dosage. Peripheral vascular disease impairs distribution, may require an
increased dose. When the same pathway metabolizes two medications, they compete for
metabolism, potentially increasing the concentration of one or both medications. Requiring
deceasing the dose of one or both medications
Quiz____?
A patient asks the nurse why a lower dose of IV pain medication is being given than the
previous oral dose. What is the nurse's best response to the patient?
A."Medications given orally bypass the portal circulatory system."
B."Medications given intravenously are not affected by the first-pass effect."
C."Drugs administered intravenously enter the portal system before systemic distribution."
D."A large percentage of an intravenously administered drug is metabolized into inactive
metabolites in the liver." -
Answer✓✓
Ans: B
Rationale: When drugs with a high first-pass effect are administered orally, a large amount of
drug may be metabolized before it reaches the systemic circulation. The same drug given IV will
4
