521- PHARMACOLOGY TEST
QUESTIONS AND ANSWERS
What kjis kjpharmacodynamics? kj- kjANS--what kja kjdrug kjdoes kjto kjyour kjbody
what kjis kjpharmacokinetics? kj- kjANS--what kjyour kjbody kjdoes kjto kjthe kjdrug
The kjprocess kjof kjthe kjdrug kjbeing kjprepared kjto kjenter kjthe kjsystemic
kjcirculation:Entrance kjvaries kjon kjthe kjroute kjof kjadministration
Includes kjdrug kjmovement kjacross kjcell kjmembranes kjinto kjthe kjcirculation kj- kjANS--
absorption
what kjis kjparental kjabsorption kjroute kjmean? kj- kjANS--bypass kjGI kjtract
what kjroute kjcan kjbe kjeither kjenteral kjand kjparenteral? kj- kjANS--rectal
enteral kjis kjwhat kjroute kjfor kjmed kjadministration? kj- kjANS--oral
what kjroute kjof kjabsorption kjhas kj100% kjbioavailability, kjunchanged kjand kjavailable kjto
kjbind kjto kja kjreceptor.
Precise kjdosing, kjEasy kjaccess, kjBolus kjand kjcontinuous kjdosing kj- kjANS--IV
What kjaccounts kjfor kjthe kjfollowing kjcharacteristics? kjthe kjtime kjdelay kjbetween
kjchanges kjin kjplasma kjconcentration kjand kjdrug kjeffect. kjaccounts kjfor kjthe kjtime
kjrequired kjfor kjdrug kjto kjdiffuse kjfrom kjthe kjplasma kjto kjthe kjsite kjof kjaction kjplus kjthe
kjtime kjrequired kjto kjillicit kja kjdrug kjeffect? kj- kjANS--biophase
What kjroute kjis kjthe kjonly kjroute kjthat kjdoesn't kjpass kjthrough kjbiological kjmembranes?
kj- kjANS--IV
The kjroute kjof kjabsorption kjinfluences? kj- kjANS--drug kjabsorption, kjbioavailabity, kjhow
kjfast kjit kjworks
What kjare kjthe kjabsorption kjsites kjfor kjoral kjadministration? kj- kjANS--small kjintestine
kj(mainly), kjstomach, kjlarge kjintestine
What kjfactor kjfavors kjabsorption kjin kjan kjoral kjmed? kj- kjANS--non-ionized, kjlipid
kjsoluble, kjsmaller kjmolecules
What kjtype kjof kjacid kjis kjreadily kjabsorbed kjby kjstomach? kj- kjANS--weak
Weak kjacids kjmay kjbe kjhighly kj________ kjin kjthe kjalkaline kjintestinal kjpH.
, (This kjeffect kjis kjcounterbalanced kjby kjthe kjlarge kjsurface-area kjeffect kjof kjthe kjsmall
kjintestine) kj- kjANS--ionized
The kjfollowing kjdescribes kjwhat kjroute? kjAdvantages: kjSustained, kjtherapeutic kjplasma
kjlevels. kj
Reduced kjpeaks kj/valleys kjassociated kjwith kjintermittent kjdrug kjadministration. kjAvoids
kjcontinuous kjinfusion kjtechnique kjdifficulties. kjLow kjside kjeffect kjincidence kj(smaller
kjdoses). kjGenerally kjgood kjpatient kjcompliance. kj- kjANS--transdermal
Factors kjcontributing kjto kjreliable kj______________ kjabsorption: kj
Molecular kjweight kj< kj1000 kj
pH kjrange kj5 kj- kj9. kjNo kjhistamine kj- kjreleasing kjaction. kjDaily kjdrug kjrequirement kj<
kj10 kjmg. kjUse kjof kjadjunct kjvasoactive kjdrugs
Epinephrine kj- kjANS--transdermal
which kjroute kjhas kjan kjunpredictable kjpharmacological kjresponse? kj- kjANS--rectal
kj(Difficulty kjin kjprecise kjplacement/ kjMay kjproduce kjmucosal kjirritation)
Which kjroute kjhas kjrapid kjand kjpredictible kjadministration kjroute?Ensures kjactive kjdrug
kjabsorption kj
Avoids kjfirst kjpass kjmetabolism
Route kjof kjadministration kjacceptable kjfor:
Uncooperative kjpatients kj
Unconscious kjpatients
One kj- kjtime kjmedications kj- kjANS--subq kjand kjIM
what kjfactors kjrate kjof kjsystemic kjabsorption kjof kjsubQ kjand kjIM kjmedication? kj- kjANS--
surface kjarea, kjdrug kjsoluability, kjaqeous kjchannels kj(promote kjhigh kjdiffusion kjrates kjof
kjdrugs, kjindependent kjof kjtheir kjlipid kjsolubility)
what kjare kjsome kjcharacteristics kjof kjinhalation? kj- kjANS--rapid kjpeak kjarterial
kjconcentration kj(large kjsurface kjarea), kjalveoli kjare kjreservoir, kjavoids kjhepatic kj1st
kjpass kjmetabolism
what kjcauses kjpulmonary kjfirst kjpass kjmetabolism, kjirritation, kjrequires kjspecial
kjequipment, kjand kjcan kjbe kjaltered kjby kjvasoactive kjmedication? kj- kjANS--inhalation
what kjis kjthe kjdifference kjbetween kjproximal kjrectal kjand kjdistal kjrectal kjadministration?
kj- kjANS--proximal kjin kjsuperior kjveins kjand kjenters kjportal kjvenous kjsystem kj; kjdistal kjin
kjinferior kjhemorrhoidal kjveins kjand kjenters kjsystemic kjcirculation kjwithout kjpassing
kjthrough kjliver
vessel kjpoor kjgroups kj(2) kj- kjANS--adipose kjbone
vessel kjrich kjgroup kj(4) kj- kjANS--brain, kjheart, kjlung, kjkidney
QUESTIONS AND ANSWERS
What kjis kjpharmacodynamics? kj- kjANS--what kja kjdrug kjdoes kjto kjyour kjbody
what kjis kjpharmacokinetics? kj- kjANS--what kjyour kjbody kjdoes kjto kjthe kjdrug
The kjprocess kjof kjthe kjdrug kjbeing kjprepared kjto kjenter kjthe kjsystemic
kjcirculation:Entrance kjvaries kjon kjthe kjroute kjof kjadministration
Includes kjdrug kjmovement kjacross kjcell kjmembranes kjinto kjthe kjcirculation kj- kjANS--
absorption
what kjis kjparental kjabsorption kjroute kjmean? kj- kjANS--bypass kjGI kjtract
what kjroute kjcan kjbe kjeither kjenteral kjand kjparenteral? kj- kjANS--rectal
enteral kjis kjwhat kjroute kjfor kjmed kjadministration? kj- kjANS--oral
what kjroute kjof kjabsorption kjhas kj100% kjbioavailability, kjunchanged kjand kjavailable kjto
kjbind kjto kja kjreceptor.
Precise kjdosing, kjEasy kjaccess, kjBolus kjand kjcontinuous kjdosing kj- kjANS--IV
What kjaccounts kjfor kjthe kjfollowing kjcharacteristics? kjthe kjtime kjdelay kjbetween
kjchanges kjin kjplasma kjconcentration kjand kjdrug kjeffect. kjaccounts kjfor kjthe kjtime
kjrequired kjfor kjdrug kjto kjdiffuse kjfrom kjthe kjplasma kjto kjthe kjsite kjof kjaction kjplus kjthe
kjtime kjrequired kjto kjillicit kja kjdrug kjeffect? kj- kjANS--biophase
What kjroute kjis kjthe kjonly kjroute kjthat kjdoesn't kjpass kjthrough kjbiological kjmembranes?
kj- kjANS--IV
The kjroute kjof kjabsorption kjinfluences? kj- kjANS--drug kjabsorption, kjbioavailabity, kjhow
kjfast kjit kjworks
What kjare kjthe kjabsorption kjsites kjfor kjoral kjadministration? kj- kjANS--small kjintestine
kj(mainly), kjstomach, kjlarge kjintestine
What kjfactor kjfavors kjabsorption kjin kjan kjoral kjmed? kj- kjANS--non-ionized, kjlipid
kjsoluble, kjsmaller kjmolecules
What kjtype kjof kjacid kjis kjreadily kjabsorbed kjby kjstomach? kj- kjANS--weak
Weak kjacids kjmay kjbe kjhighly kj________ kjin kjthe kjalkaline kjintestinal kjpH.
, (This kjeffect kjis kjcounterbalanced kjby kjthe kjlarge kjsurface-area kjeffect kjof kjthe kjsmall
kjintestine) kj- kjANS--ionized
The kjfollowing kjdescribes kjwhat kjroute? kjAdvantages: kjSustained, kjtherapeutic kjplasma
kjlevels. kj
Reduced kjpeaks kj/valleys kjassociated kjwith kjintermittent kjdrug kjadministration. kjAvoids
kjcontinuous kjinfusion kjtechnique kjdifficulties. kjLow kjside kjeffect kjincidence kj(smaller
kjdoses). kjGenerally kjgood kjpatient kjcompliance. kj- kjANS--transdermal
Factors kjcontributing kjto kjreliable kj______________ kjabsorption: kj
Molecular kjweight kj< kj1000 kj
pH kjrange kj5 kj- kj9. kjNo kjhistamine kj- kjreleasing kjaction. kjDaily kjdrug kjrequirement kj<
kj10 kjmg. kjUse kjof kjadjunct kjvasoactive kjdrugs
Epinephrine kj- kjANS--transdermal
which kjroute kjhas kjan kjunpredictable kjpharmacological kjresponse? kj- kjANS--rectal
kj(Difficulty kjin kjprecise kjplacement/ kjMay kjproduce kjmucosal kjirritation)
Which kjroute kjhas kjrapid kjand kjpredictible kjadministration kjroute?Ensures kjactive kjdrug
kjabsorption kj
Avoids kjfirst kjpass kjmetabolism
Route kjof kjadministration kjacceptable kjfor:
Uncooperative kjpatients kj
Unconscious kjpatients
One kj- kjtime kjmedications kj- kjANS--subq kjand kjIM
what kjfactors kjrate kjof kjsystemic kjabsorption kjof kjsubQ kjand kjIM kjmedication? kj- kjANS--
surface kjarea, kjdrug kjsoluability, kjaqeous kjchannels kj(promote kjhigh kjdiffusion kjrates kjof
kjdrugs, kjindependent kjof kjtheir kjlipid kjsolubility)
what kjare kjsome kjcharacteristics kjof kjinhalation? kj- kjANS--rapid kjpeak kjarterial
kjconcentration kj(large kjsurface kjarea), kjalveoli kjare kjreservoir, kjavoids kjhepatic kj1st
kjpass kjmetabolism
what kjcauses kjpulmonary kjfirst kjpass kjmetabolism, kjirritation, kjrequires kjspecial
kjequipment, kjand kjcan kjbe kjaltered kjby kjvasoactive kjmedication? kj- kjANS--inhalation
what kjis kjthe kjdifference kjbetween kjproximal kjrectal kjand kjdistal kjrectal kjadministration?
kj- kjANS--proximal kjin kjsuperior kjveins kjand kjenters kjportal kjvenous kjsystem kj; kjdistal kjin
kjinferior kjhemorrhoidal kjveins kjand kjenters kjsystemic kjcirculation kjwithout kjpassing
kjthrough kjliver
vessel kjpoor kjgroups kj(2) kj- kjANS--adipose kjbone
vessel kjrich kjgroup kj(4) kj- kjANS--brain, kjheart, kjlung, kjkidney
