NR546 WEEK 5 TEST YOUR KNOWLEDGE
100% CORRECT!!
,Pharmacologic Treatment of Major Depressive Disorder - ANSWER Selective serotonin
reuptake inhibitors (SSRIs)
Serotonin-norepinephrine reuptake inhibitors (SNRIs)
Norepinephrine and dopamine reuptake inhibitors (NDRIs)
Serotonin antagonists and reuptake inhibitors (SARIs)
Miscellaneous antidepressants
Monoamine oxidase (MAO)-B inhibitors
Adjunct: antipsychotics
Pharmacologic Treatment of Bipolar Disorder - ANSWER Lithium
Anticonvulsants
Second generation antipsychotics
Mood disorders: role of the psychiatric mental health nurse practitioner (PMHNP) is to:
- ANSWER determine the malfunctioning brain circuit responsible for the client's
presenting symptoms and select the appropriate medication that targets the associated
neurotransmitter(s)
Mood disorders manifest across a spectrum from: - ANSWER mania to major
depressive disorder (MDD)
Unipolar depression - ANSWER major depressive disorder (MDD)
one of the most common mental disorders
-Approximately 7.1% of adults in the U.S. had episode in last year, prevalence highest
(13.1%) among individuals aged 18-25
S/S
-depressed mood
-loss of interest or pleasure in daily activities
-irritability
-withdrawal
-problems with sleep, eating, energy, concentration, or self-worth
-severe depression: may experience thoughts of suicide or psychotic symptoms.
Bipolar disorder (BD) - ANSWER Chronic condition characterized by extreme
fluctuations in mood, energy, and ability to function
-Moods may be manic, hypomanic, or depressed and may include mixed mood or
psychotic features
-many have only experienced only one manic episode in their lifetime
-Mood fluctuations may be separated by periods of high stability or may cycle rapidly
, -diagnosed when a client has one or more episodes of mania or hypomania with a
history of one or more major depressive episodes
-high risk for suicide
Cyclothymia: - ANSWER involves the chronic presentation of hypomanic and
depressive symptoms that do not meet the diagnostic criteria for a major depressive or
manic/hypomanic episode.
If bipolar depression is mistaken for MDD: - ANSWER antidepressant therapy may
precipitate a manic episode or induce rapid-cycling bipolar depression
-may contribute to the increased incidence of death by suicide in children and adults
younger than 25
Antidepressants are used cautiously in clients with bipolar disorder and never as
________________. - ANSWER monotherapy
-Antidepressants should be combined with a mood stabilizer to prevent the onset of a
hypomanic or manic episode
DA, NE Dysfunction causes what mood related symptoms - ANSWER Decreased
positive affect:
depressed mood
loss of joy
lack of interest
loss of energy
decreased alertness
decreased self-confidence
appetite changes
5HT, NE Dysfunction causes what mood related symptoms - ANSWER Increased
negative affect:
depressed mood
guilt
fear/anxiety
hostility
irritability
loneliness
appetite changes
neurobiological factors that contribute to mood and mood disorders: Genetics -
ANSWER MDD and BD are heritable disorders
-genetic factors 31-42% of the disease risk in MDD and 59-85% in BD
100% CORRECT!!
,Pharmacologic Treatment of Major Depressive Disorder - ANSWER Selective serotonin
reuptake inhibitors (SSRIs)
Serotonin-norepinephrine reuptake inhibitors (SNRIs)
Norepinephrine and dopamine reuptake inhibitors (NDRIs)
Serotonin antagonists and reuptake inhibitors (SARIs)
Miscellaneous antidepressants
Monoamine oxidase (MAO)-B inhibitors
Adjunct: antipsychotics
Pharmacologic Treatment of Bipolar Disorder - ANSWER Lithium
Anticonvulsants
Second generation antipsychotics
Mood disorders: role of the psychiatric mental health nurse practitioner (PMHNP) is to:
- ANSWER determine the malfunctioning brain circuit responsible for the client's
presenting symptoms and select the appropriate medication that targets the associated
neurotransmitter(s)
Mood disorders manifest across a spectrum from: - ANSWER mania to major
depressive disorder (MDD)
Unipolar depression - ANSWER major depressive disorder (MDD)
one of the most common mental disorders
-Approximately 7.1% of adults in the U.S. had episode in last year, prevalence highest
(13.1%) among individuals aged 18-25
S/S
-depressed mood
-loss of interest or pleasure in daily activities
-irritability
-withdrawal
-problems with sleep, eating, energy, concentration, or self-worth
-severe depression: may experience thoughts of suicide or psychotic symptoms.
Bipolar disorder (BD) - ANSWER Chronic condition characterized by extreme
fluctuations in mood, energy, and ability to function
-Moods may be manic, hypomanic, or depressed and may include mixed mood or
psychotic features
-many have only experienced only one manic episode in their lifetime
-Mood fluctuations may be separated by periods of high stability or may cycle rapidly
, -diagnosed when a client has one or more episodes of mania or hypomania with a
history of one or more major depressive episodes
-high risk for suicide
Cyclothymia: - ANSWER involves the chronic presentation of hypomanic and
depressive symptoms that do not meet the diagnostic criteria for a major depressive or
manic/hypomanic episode.
If bipolar depression is mistaken for MDD: - ANSWER antidepressant therapy may
precipitate a manic episode or induce rapid-cycling bipolar depression
-may contribute to the increased incidence of death by suicide in children and adults
younger than 25
Antidepressants are used cautiously in clients with bipolar disorder and never as
________________. - ANSWER monotherapy
-Antidepressants should be combined with a mood stabilizer to prevent the onset of a
hypomanic or manic episode
DA, NE Dysfunction causes what mood related symptoms - ANSWER Decreased
positive affect:
depressed mood
loss of joy
lack of interest
loss of energy
decreased alertness
decreased self-confidence
appetite changes
5HT, NE Dysfunction causes what mood related symptoms - ANSWER Increased
negative affect:
depressed mood
guilt
fear/anxiety
hostility
irritability
loneliness
appetite changes
neurobiological factors that contribute to mood and mood disorders: Genetics -
ANSWER MDD and BD are heritable disorders
-genetic factors 31-42% of the disease risk in MDD and 59-85% in BD
