NURS 5334 Advanced Pharmacotherapeutics

NURS 5334 Advanced Pharmacotherapeutics Final Review with Questions and Answers Why do many medications lack pediatric dosing information in their drug labeling? A. Most medications are not used in pediatric patients. B. There is a lack of evidence-based literature on the safe and effective use of medications in children. C. The FDA does not allow pediatric dosing information in product labeling. D. Only products available as oral liquid formulations are required to contain pediatric dosing information in their labeling. ANSWER B. There is a lack of evidence-based literature on the safe and effective use of medications in children. Why are Neonates at greater risk for toxicity with highly protein-bound drugs? A. Protein binding is decreased in neonates increasing the amount of free drug available. B. The protein-bound drugs are not eliminated effectively in neonates. C. Neonates are unable to metabolize these highly protein-bound drugs. D. Protein binding is increased in neonates, making measurement of serum levels of the drug inaccurate. ANSWER A. Protein binding is decreased in neonates increasing the amount of free drug available. At what age are adult levels of renal function achieved? • A. 6 months B. 12 months C. 24 months