,Chapter 01: Drug Regulation, Actions, and Responses
oi oi oi oi oi oi oi
Workman & LaCharity: Understanding Pharmacology: Essentials for Medication Safety, 3rd
oi oi oi oi oi oi oi oi oi i
o
Edition
MULTIPLE CHOICE B oi oi
ASIC CONCEPTS oi
1. Which health care professional has the major responsibility for dispensing prescribed
oi oi oi oi oi oi oi oi oi oi i
o
drugs under the direction of a pharmacist?
oi oi oi oi oi oi
a. Physician
b Nurse practitioner oi
.
c. Licensed nurse oi
d Pharmacy technician oi
.
ANS: D o i
The physician and nurse practitioner have the major responsibility for prescribing drugs, not dis
oi oi oi oi oi oi oi oi oi oi oi oi oi
pensing them. The licensed nurse has the primary responsibility for administering drugs, althou
oi oi oi oi oi oi oi oi oi oi oi oi
gh under some circumstances a licensed nurse may dispense prescribed drugs but this isnot his o
oi oi oi oi oi oi oi oi oi oi oi oi oi i
o oi oi
r her major responsibility in drug therapy. The pharmacy technician has the major responsibility
oi oi oi oi oi oi oi oi oi oi oi oi oi o
of dispensing prescribed drugs under the direction of a licensed pharmacist.
i oi oi oi oi oi oi oi oi oi oi
DIF: Cognitive Level: Remembering oi oi REF: p. 3 oi
2. Which term describes the effect of a drug that improves body function?
oi oi oi oi oi oi oi oi oi oi oi
a. Side effect oi
b Intended action oi
.
c. Adverse reaction oi
d Idiosyncratic response oi
.
ANS: B o i
The purpose of drug therapy is to take a drug to prevent, reduce, or correct a health problem
oi oi oi oi oi oi oi oi oi oi oi oi oi oi oi oi oi
.This response is any drug’s intended action also known as a therapeutic response.
i
o oi oi oi oi oi oi oi oi oi oi oi oi
DIF: Cognitive Level: Remembering oi oi REF: p. 3 oi
3. Which type of drug name is ―owned‖ by the company that manufactures it?
oi oi oi oi oi oi oi oi oi oi oi oi
a. Generic name oi
b Chemical name oi
, .
c. Category name oi
d Trade name oi
.
ANS: D o i
The chemical name is a drug’s exact chemical composition. The generic name is the name assig
oi oi oi oi oi oi oi oi oi oi oi oi oi oi oi
ned to the drug by the U.S. Adopted Names Council and is not owned by anyone. The category
oi oi oi oi oi oi oi oi oi oi oi oi oi oi oi oi oi oi
name refers to the type of drug (what it does or what it is used for) and is not an actualdrug nam
oi oi oi oi oi oi oi oi oi oi oi oi oi oi oi oi oi oi oi oi i
o oi
e. The trade name (brand name) is the name provided and owned by a specific drug’s manufact
oi oi oi oi oi oi oi oi oi oi oi oi oi oi oi oi
urer.
DIF: Cognitive Level: Remembering oi oi REF: p. 4 oi
4. Which drug or drug class is a ―high alert‖ drug?
oi oi oi oi oi oi oi oi oi
a. Penicillin
b Insulin
.
c. NSAIDs
d Calcium
.
ANS: B o i
A high alert drug is one in which harm is likely to result if given at the wrong dose, to the wrong
oi oi oi oi oi oi oi oi oi oi oi oi oi oi oi oi oi oi oi oi oi i
o
patient, or not given to the correct patient. Drugs classified as high alert drugs include potassium
oi oi oi oi oi oi oi oi oi oi oi oi oi oi oi
,narcotics (opioids), insulin, cancer chemotherapy drugs, and heparin (or any drug that strongly a
i
o oi oi oi oi oi oi oi oi oi oi oi oi oi
ffects blood clotting). Penicillin, NSAIDs, and calcium are not considered high alert drugs.
oi oi oi oi oi oi oi oi oi oi oi oi
DIF: Cognitive Level: Remembering oi oi REF: p. 4 oi
5. What is the term for a drug that has the same action as a naturally occurring bod
oi oi oi oi oi oi oi oi oi oi oi oi oi oi oi oi
yhormone or enzyme?
oi oi oi
a. Agonist
b Blocking agent oi
.
c. Chemical
d Duplicator
.
ANS: A o i
A drug agonist is an extrinsic drug that activates the receptor sites of a cell and mimics th
oi oi oi oi oi oi oi oi oi oi oi oi oi oi oi oi oi
eactions of naturally occurring body substances (intrinsic drugs). A blocking agent is a dru
i
o oi oi oi oi oi oi oi oi oi oi oi oi oi
g
, antagonist. A chemical would not necessarily be a drug at all. A duplicator is not a pharmacologict
oi oi oi oi oi oi oi oi oi oi oi oi oi oi oi oi i
o
erm.
DIF: Cognitive Level: Remembering oi oi REF: pp. 6-7 oi
6. Which term describes how the body affects drug activity? oi oi oi oi oi oi oi oi
a. Drug potency oi
b Pharmacodynamics
.
c. Therapeutic effect oi
d Pharmacokinetics
.
ANS: D o i
The term pharmacokinetics refers to drug metabolism and how the body changes a drug. Pharmac
oi oi oi oi oi oi oi oi oi oi oi oi oi oi
odynamics refers to how a drug works to change body function. Drug potency refers tohow strongl
oi oi oi oi oi oi oi oi oi oi oi oi oi oi i
o oi
y or to what degree a drug exerts its effects. The therapeutic effect is closer to pharmacodynamics
oi oi oi oi oi oi oi oi oi oi oi oi oi oi oi oi
, meaning how a drug works to change body function.
oi oi oi oi oi oi oi oi oi
DIF: Cognitive Level: Remembering oi oi REF: p. 10 oi
7. In the United States, which group is responsible for enforcing established standards for
oi oi oi oi oi oi oi oi oi oi oi oi i
o
drug manufacturing? oi
a. U.S. Pharmacopeia oi
b National Institutes of Health oi oi oi
.
c. Food and Drug Administration oi oi oi
d Association of Pharmaceutical Manufacturers oi oi oi
.
ANS: C o i
The standards for drug manufacture are established by the U.S. Pharmacopeia. These standards
oi oi oi oi oi oi oi oi oi oi oi oi oi
are enforced by the Food and Drug Administration. Neither the National Institutes of Health nort
oi oi oi oi oi oi oi oi oi oi oi oi oi oi i
o
he Association of Pharmaceutical Manufacturers has any authority to enforce drug standards.
oi oi oi oi oi oi oi oi oi oi oi
DIF: Cognitive Level: Remembering oi oi REF: p. 5 oi
8. Which factor is a major disadvantage of the transdermal drug delivery route?
oi oi oi oi oi oi oi oi oi oi oi
a. Only a prescriber can administer drugs by the transdermal route.
oi oi oi oi oi oi oi oi oi
b Transdermal drugs must be sterile rather than clean. oi oi oi oi oi oi oi
.
c. First pass drug loss by this route is the most extensive.
oi oi oi oi oi oi oi oi oi oi
d Drug absorption is dependent on adequate circulation.
oi oi oi oi oi oi
oi oi oi oi oi oi oi
Workman & LaCharity: Understanding Pharmacology: Essentials for Medication Safety, 3rd
oi oi oi oi oi oi oi oi oi i
o
Edition
MULTIPLE CHOICE B oi oi
ASIC CONCEPTS oi
1. Which health care professional has the major responsibility for dispensing prescribed
oi oi oi oi oi oi oi oi oi oi i
o
drugs under the direction of a pharmacist?
oi oi oi oi oi oi
a. Physician
b Nurse practitioner oi
.
c. Licensed nurse oi
d Pharmacy technician oi
.
ANS: D o i
The physician and nurse practitioner have the major responsibility for prescribing drugs, not dis
oi oi oi oi oi oi oi oi oi oi oi oi oi
pensing them. The licensed nurse has the primary responsibility for administering drugs, althou
oi oi oi oi oi oi oi oi oi oi oi oi
gh under some circumstances a licensed nurse may dispense prescribed drugs but this isnot his o
oi oi oi oi oi oi oi oi oi oi oi oi oi i
o oi oi
r her major responsibility in drug therapy. The pharmacy technician has the major responsibility
oi oi oi oi oi oi oi oi oi oi oi oi oi o
of dispensing prescribed drugs under the direction of a licensed pharmacist.
i oi oi oi oi oi oi oi oi oi oi
DIF: Cognitive Level: Remembering oi oi REF: p. 3 oi
2. Which term describes the effect of a drug that improves body function?
oi oi oi oi oi oi oi oi oi oi oi
a. Side effect oi
b Intended action oi
.
c. Adverse reaction oi
d Idiosyncratic response oi
.
ANS: B o i
The purpose of drug therapy is to take a drug to prevent, reduce, or correct a health problem
oi oi oi oi oi oi oi oi oi oi oi oi oi oi oi oi oi
.This response is any drug’s intended action also known as a therapeutic response.
i
o oi oi oi oi oi oi oi oi oi oi oi oi
DIF: Cognitive Level: Remembering oi oi REF: p. 3 oi
3. Which type of drug name is ―owned‖ by the company that manufactures it?
oi oi oi oi oi oi oi oi oi oi oi oi
a. Generic name oi
b Chemical name oi
, .
c. Category name oi
d Trade name oi
.
ANS: D o i
The chemical name is a drug’s exact chemical composition. The generic name is the name assig
oi oi oi oi oi oi oi oi oi oi oi oi oi oi oi
ned to the drug by the U.S. Adopted Names Council and is not owned by anyone. The category
oi oi oi oi oi oi oi oi oi oi oi oi oi oi oi oi oi oi
name refers to the type of drug (what it does or what it is used for) and is not an actualdrug nam
oi oi oi oi oi oi oi oi oi oi oi oi oi oi oi oi oi oi oi oi i
o oi
e. The trade name (brand name) is the name provided and owned by a specific drug’s manufact
oi oi oi oi oi oi oi oi oi oi oi oi oi oi oi oi
urer.
DIF: Cognitive Level: Remembering oi oi REF: p. 4 oi
4. Which drug or drug class is a ―high alert‖ drug?
oi oi oi oi oi oi oi oi oi
a. Penicillin
b Insulin
.
c. NSAIDs
d Calcium
.
ANS: B o i
A high alert drug is one in which harm is likely to result if given at the wrong dose, to the wrong
oi oi oi oi oi oi oi oi oi oi oi oi oi oi oi oi oi oi oi oi oi i
o
patient, or not given to the correct patient. Drugs classified as high alert drugs include potassium
oi oi oi oi oi oi oi oi oi oi oi oi oi oi oi
,narcotics (opioids), insulin, cancer chemotherapy drugs, and heparin (or any drug that strongly a
i
o oi oi oi oi oi oi oi oi oi oi oi oi oi
ffects blood clotting). Penicillin, NSAIDs, and calcium are not considered high alert drugs.
oi oi oi oi oi oi oi oi oi oi oi oi
DIF: Cognitive Level: Remembering oi oi REF: p. 4 oi
5. What is the term for a drug that has the same action as a naturally occurring bod
oi oi oi oi oi oi oi oi oi oi oi oi oi oi oi oi
yhormone or enzyme?
oi oi oi
a. Agonist
b Blocking agent oi
.
c. Chemical
d Duplicator
.
ANS: A o i
A drug agonist is an extrinsic drug that activates the receptor sites of a cell and mimics th
oi oi oi oi oi oi oi oi oi oi oi oi oi oi oi oi oi
eactions of naturally occurring body substances (intrinsic drugs). A blocking agent is a dru
i
o oi oi oi oi oi oi oi oi oi oi oi oi oi
g
, antagonist. A chemical would not necessarily be a drug at all. A duplicator is not a pharmacologict
oi oi oi oi oi oi oi oi oi oi oi oi oi oi oi oi i
o
erm.
DIF: Cognitive Level: Remembering oi oi REF: pp. 6-7 oi
6. Which term describes how the body affects drug activity? oi oi oi oi oi oi oi oi
a. Drug potency oi
b Pharmacodynamics
.
c. Therapeutic effect oi
d Pharmacokinetics
.
ANS: D o i
The term pharmacokinetics refers to drug metabolism and how the body changes a drug. Pharmac
oi oi oi oi oi oi oi oi oi oi oi oi oi oi
odynamics refers to how a drug works to change body function. Drug potency refers tohow strongl
oi oi oi oi oi oi oi oi oi oi oi oi oi oi i
o oi
y or to what degree a drug exerts its effects. The therapeutic effect is closer to pharmacodynamics
oi oi oi oi oi oi oi oi oi oi oi oi oi oi oi oi
, meaning how a drug works to change body function.
oi oi oi oi oi oi oi oi oi
DIF: Cognitive Level: Remembering oi oi REF: p. 10 oi
7. In the United States, which group is responsible for enforcing established standards for
oi oi oi oi oi oi oi oi oi oi oi oi i
o
drug manufacturing? oi
a. U.S. Pharmacopeia oi
b National Institutes of Health oi oi oi
.
c. Food and Drug Administration oi oi oi
d Association of Pharmaceutical Manufacturers oi oi oi
.
ANS: C o i
The standards for drug manufacture are established by the U.S. Pharmacopeia. These standards
oi oi oi oi oi oi oi oi oi oi oi oi oi
are enforced by the Food and Drug Administration. Neither the National Institutes of Health nort
oi oi oi oi oi oi oi oi oi oi oi oi oi oi i
o
he Association of Pharmaceutical Manufacturers has any authority to enforce drug standards.
oi oi oi oi oi oi oi oi oi oi oi
DIF: Cognitive Level: Remembering oi oi REF: p. 5 oi
8. Which factor is a major disadvantage of the transdermal drug delivery route?
oi oi oi oi oi oi oi oi oi oi oi
a. Only a prescriber can administer drugs by the transdermal route.
oi oi oi oi oi oi oi oi oi
b Transdermal drugs must be sterile rather than clean. oi oi oi oi oi oi oi
.
c. First pass drug loss by this route is the most extensive.
oi oi oi oi oi oi oi oi oi oi
d Drug absorption is dependent on adequate circulation.
oi oi oi oi oi oi