,Chapter f01: fDrug fRegulation, fActions, fand fResponses
Workman f& fLaCharity: fUnderstanding fPharmacology: fEssentials ffor fMedication fSafety, f3rd
fEdition
MULTIPLE fCHOICE
f BASIC fCONCEPTS
1. Which fhealth fcare fprofessional fhas fthe fmajor fresponsibility ffor fdispensing fprescribed
fdrugs funder fthe fdirection fof fa fpharmacist?
a. Physician
b Nurse fpractitioner
.
c. Licensed fnurse
d Pharmacy ftechnician
.
ANS: f D
The fphysician fand fnurse fpractitioner fhave fthe fmajor fresponsibility ffor fprescribing fdrugs, fnot
fdispensing fthem. fThe flicensed fnurse fhas fthe fprimary fresponsibility ffor fadministering fdrugs,
falthough funder fsome fcircumstances fa flicensed fnurse fmay fdispense fprescribed fdrugs fbut fthis fis
fnot fhis for fher fmajor fresponsibility fin fdrug ftherapy. fThe fpharmacy ftechnician fhas fthe fmajor
fresponsibility fof fdispensing fprescribed fdrugs funder fthe fdirection fof fa flicensed fpharmacist.
DIF: Cognitive fLevel: fRemembering REF: p. f3
2. Which fterm fdescribes fthe feffect fof fa fdrug fthat fimproves fbody ffunction?
a. Side feffect
b Intended faction
.
c. Adverse freaction
d Idiosyncratic fresponse
.
ANS: f B
The fpurpose fof fdrug ftherapy fis fto ftake fa fdrug fto fprevent, freduce, for fcorrect fa fhealth fproblem. fThis
fresponse fis fany fdrug’s fintended faction falso fknown fas fa ftherapeutic fresponse.
DIF: Cognitive fLevel: fRemembering REF: p. f3
3. Which ftype fof fdrug fname fis f―owned‖ fby fthe fcompany fthat fmanufactures fit?
a. Generic fname
b Chemical fname
, .
c. Category fname
d Trade fname
.
ANS: f D
The fchemical fname fis fa fdrug’s fexact fchemical fcomposition. fThe fgeneric fname fis fthe fname
fassigned fto fthe fdrug fby fthe fU.S. fAdopted fNames fCouncil fand fis fnot fowned fby fanyone. fThe
fcategory fname frefers fto fthe ftype fof fdrug f(what fit fdoes for fwhat fit fis fused ffor) fand fis fnot fan factual
fdrug fname. fThe ftrade fname f(brand fname) fis fthe fname fprovided fand fowned fby fa fspecific fdrug’s
fmanufacturer.
DIF: Cognitive fLevel: fRemembering REF: p. f4
4. Which fdrug for fdrug fclass fis fa f―high falert‖ fdrug?
a. Penicillin
b Insulin
.
c. NSAIDs
d Calcium
.
ANS: f B
A fhigh falert fdrug fis fone fin fwhich fharm fis flikely fto fresult fif fgiven fat fthe fwrong fdose, fto fthe fwrong
fpatient, for fnot fgiven fto fthe fcorrect fpatient. fDrugs fclassified fas fhigh falert fdrugs finclude fpotassium,
fnarcotics f(opioids), finsulin, fcancer fchemotherapy fdrugs, fand fheparin f(or fany fdrug fthat fstrongly
faffects fblood fclotting). fPenicillin, fNSAIDs, fand fcalcium fare fnot fconsidered fhigh falert fdrugs.
DIF: Cognitive fLevel: fRemembering REF: p. f4
5. What fis fthe fterm ffor fa fdrug fthat fhas fthe fsame faction fas fa fnaturally foccurring fbody
fhormone for fenzyme?
a. Agonist
b Blocking fagent
.
c. Chemical
d Duplicator
.
ANS: f A
A fdrug fagonist fis fan fextrinsic fdrug fthat factivates fthe freceptor fsites fof fa fcell fand fmimics fthe
factions fof fnaturally foccurring fbody fsubstances f(intrinsic fdrugs). fA fblocking fagent fis fa fdrug
, antagonist. fA fchemical fwould fnot fnecessarily fbe fa fdrug fat fall. fA fduplicator fis fnot fa fpharmacologic
fterm.
DIF: Cognitive fLevel: fRemembering REF: pp. f6-7
6. Which fterm fdescribes fhow fthe fbody faffects fdrug factivity?
a. Drug fpotency
b Pharmacodynamics
.
c. Therapeutic feffect
d Pharmacokinetics
.
ANS: f D
The fterm fpharmacokinetics frefers fto fdrug fmetabolism fand fhow fthe fbody fchanges fa fdrug.
fPharmacodynamics frefers fto fhow fa fdrug fworks fto fchange fbody ffunction. fDrug fpotency frefers fto
fhow fstrongly for fto fwhat fdegree fa fdrug fexerts fits feffects. fThe ftherapeutic feffect fis fcloser fto
fpharmacodynamics, fmeaning fhow fa fdrug fworks fto fchange fbody ffunction.
DIF: Cognitive fLevel: fRemembering REF: p. f10
7. In fthe fUnited fStates, fwhich fgroup fis fresponsible ffor fenforcing festablished fstandards ffor
fdrug fmanufacturing?
a. U.S. fPharmacopeia
b National fInstitutes fof fHealth
.
c. Food fand fDrug fAdministration
d Association fof fPharmaceutical fManufacturers
.
ANS: f C
The fstandards ffor fdrug fmanufacture fare festablished fby fthe fU.S. fPharmacopeia. fThese fstandards
fare fenforced fby fthe fFood fand fDrug fAdministration. fNeither fthe fNational fInstitutes fof fHealth fnor
fthe fAssociation fof fPharmaceutical fManufacturers fhas fany fauthority fto fenforce fdrug fstandards.
DIF: f f Cognitive fLevel: fRemembering f f f f REF: f f p. f5
8. Which ffactor fis fa fmajor fdisadvantage fof fthe ftransdermal fdrug fdelivery froute?
a. Only fa fprescriber fcan fadminister fdrugs fby fthe ftransdermal froute.
b Transdermal fdrugs fmust fbe fsterile frather fthan fclean.
.
c. First fpass fdrug floss fby fthis froute fis fthe fmost fextensive.
d Drug fabsorption fis fdependent fon fadequate fcirculation.
Workman f& fLaCharity: fUnderstanding fPharmacology: fEssentials ffor fMedication fSafety, f3rd
fEdition
MULTIPLE fCHOICE
f BASIC fCONCEPTS
1. Which fhealth fcare fprofessional fhas fthe fmajor fresponsibility ffor fdispensing fprescribed
fdrugs funder fthe fdirection fof fa fpharmacist?
a. Physician
b Nurse fpractitioner
.
c. Licensed fnurse
d Pharmacy ftechnician
.
ANS: f D
The fphysician fand fnurse fpractitioner fhave fthe fmajor fresponsibility ffor fprescribing fdrugs, fnot
fdispensing fthem. fThe flicensed fnurse fhas fthe fprimary fresponsibility ffor fadministering fdrugs,
falthough funder fsome fcircumstances fa flicensed fnurse fmay fdispense fprescribed fdrugs fbut fthis fis
fnot fhis for fher fmajor fresponsibility fin fdrug ftherapy. fThe fpharmacy ftechnician fhas fthe fmajor
fresponsibility fof fdispensing fprescribed fdrugs funder fthe fdirection fof fa flicensed fpharmacist.
DIF: Cognitive fLevel: fRemembering REF: p. f3
2. Which fterm fdescribes fthe feffect fof fa fdrug fthat fimproves fbody ffunction?
a. Side feffect
b Intended faction
.
c. Adverse freaction
d Idiosyncratic fresponse
.
ANS: f B
The fpurpose fof fdrug ftherapy fis fto ftake fa fdrug fto fprevent, freduce, for fcorrect fa fhealth fproblem. fThis
fresponse fis fany fdrug’s fintended faction falso fknown fas fa ftherapeutic fresponse.
DIF: Cognitive fLevel: fRemembering REF: p. f3
3. Which ftype fof fdrug fname fis f―owned‖ fby fthe fcompany fthat fmanufactures fit?
a. Generic fname
b Chemical fname
, .
c. Category fname
d Trade fname
.
ANS: f D
The fchemical fname fis fa fdrug’s fexact fchemical fcomposition. fThe fgeneric fname fis fthe fname
fassigned fto fthe fdrug fby fthe fU.S. fAdopted fNames fCouncil fand fis fnot fowned fby fanyone. fThe
fcategory fname frefers fto fthe ftype fof fdrug f(what fit fdoes for fwhat fit fis fused ffor) fand fis fnot fan factual
fdrug fname. fThe ftrade fname f(brand fname) fis fthe fname fprovided fand fowned fby fa fspecific fdrug’s
fmanufacturer.
DIF: Cognitive fLevel: fRemembering REF: p. f4
4. Which fdrug for fdrug fclass fis fa f―high falert‖ fdrug?
a. Penicillin
b Insulin
.
c. NSAIDs
d Calcium
.
ANS: f B
A fhigh falert fdrug fis fone fin fwhich fharm fis flikely fto fresult fif fgiven fat fthe fwrong fdose, fto fthe fwrong
fpatient, for fnot fgiven fto fthe fcorrect fpatient. fDrugs fclassified fas fhigh falert fdrugs finclude fpotassium,
fnarcotics f(opioids), finsulin, fcancer fchemotherapy fdrugs, fand fheparin f(or fany fdrug fthat fstrongly
faffects fblood fclotting). fPenicillin, fNSAIDs, fand fcalcium fare fnot fconsidered fhigh falert fdrugs.
DIF: Cognitive fLevel: fRemembering REF: p. f4
5. What fis fthe fterm ffor fa fdrug fthat fhas fthe fsame faction fas fa fnaturally foccurring fbody
fhormone for fenzyme?
a. Agonist
b Blocking fagent
.
c. Chemical
d Duplicator
.
ANS: f A
A fdrug fagonist fis fan fextrinsic fdrug fthat factivates fthe freceptor fsites fof fa fcell fand fmimics fthe
factions fof fnaturally foccurring fbody fsubstances f(intrinsic fdrugs). fA fblocking fagent fis fa fdrug
, antagonist. fA fchemical fwould fnot fnecessarily fbe fa fdrug fat fall. fA fduplicator fis fnot fa fpharmacologic
fterm.
DIF: Cognitive fLevel: fRemembering REF: pp. f6-7
6. Which fterm fdescribes fhow fthe fbody faffects fdrug factivity?
a. Drug fpotency
b Pharmacodynamics
.
c. Therapeutic feffect
d Pharmacokinetics
.
ANS: f D
The fterm fpharmacokinetics frefers fto fdrug fmetabolism fand fhow fthe fbody fchanges fa fdrug.
fPharmacodynamics frefers fto fhow fa fdrug fworks fto fchange fbody ffunction. fDrug fpotency frefers fto
fhow fstrongly for fto fwhat fdegree fa fdrug fexerts fits feffects. fThe ftherapeutic feffect fis fcloser fto
fpharmacodynamics, fmeaning fhow fa fdrug fworks fto fchange fbody ffunction.
DIF: Cognitive fLevel: fRemembering REF: p. f10
7. In fthe fUnited fStates, fwhich fgroup fis fresponsible ffor fenforcing festablished fstandards ffor
fdrug fmanufacturing?
a. U.S. fPharmacopeia
b National fInstitutes fof fHealth
.
c. Food fand fDrug fAdministration
d Association fof fPharmaceutical fManufacturers
.
ANS: f C
The fstandards ffor fdrug fmanufacture fare festablished fby fthe fU.S. fPharmacopeia. fThese fstandards
fare fenforced fby fthe fFood fand fDrug fAdministration. fNeither fthe fNational fInstitutes fof fHealth fnor
fthe fAssociation fof fPharmaceutical fManufacturers fhas fany fauthority fto fenforce fdrug fstandards.
DIF: f f Cognitive fLevel: fRemembering f f f f REF: f f p. f5
8. Which ffactor fis fa fmajor fdisadvantage fof fthe ftransdermal fdrug fdelivery froute?
a. Only fa fprescriber fcan fadminister fdrugs fby fthe ftransdermal froute.
b Transdermal fdrugs fmust fbe fsterile frather fthan fclean.
.
c. First fpass fdrug floss fby fthis froute fis fthe fmost fextensive.
d Drug fabsorption fis fdependent fon fadequate fcirculation.
