UWorld Biochem Exam Real Questions
100% Solved Correct
Hereditary Fructose Intolerance - ANSWER✔✔-Aldolase B deficiency.
Symptoms: vomiting and hypoglycemia when fructose introduced to diet. Failure to
thrive, jaundice, and hepatomegaly.
1g of protein or carbohydrate = ? kcal
1g of fat = ? kcal - ANSWER✔✔-protein & carbs = 4 calories
fat = 9 calories
Wernicke-Korsakoff syndrome - ANSWER✔✔-Organic brain syndrome resulting from
prolonged heavy alcohol use, involving confusion, unintelligible speech, and loss of
motor coordination. It may be caused by a deficiency of *thiamine*, a vitamin
metabolized poorly by heavy drinkers.
Diarrhea, dementia, and dermatitis are indicative of what disease? What enzymes are
impaired? - ANSWER✔✔-pellagra - caused by niacin (B3) deficiency. Enzymes
impaired are the dehydrogenases.
COPYRIGHT © 2025 BY OLIVIA GREENWAYS, ALL RIGHTS RESERVED 1
, What enzymes are encoded by the lac operon? - ANSWER✔✔-beta-galactosidase,
permease, and transacetylase
classic example of polycistronic mRNA - ANSWER✔✔-the lac operon in E. coli
Beriberi - ANSWER✔✔-Thiamine (B1) deficiency. Causes peripheral neuropathy,
cardiomyopathy, high-output CHF, peripheral edema, and tachycardia. (Wet beriberi
includes the cardiac symptoms)
The ammonia buffer system helps to eliminate excess hydrogen ions by - ANSWER✔✔-
metabolism of glutamine to glutamate in renal tubular cells, generating ammonium that
is excreted in the urine
Which dietary sugar is metabolized the fastest? - ANSWER✔✔-Fructose.
Phosphorylated in the liver to F-1-P, which bypasses the RLS of PFK-1 in glycolysis.
Tagging with phosphorylated mannose residues marks proteins for delivery to... -
ANSWER✔✔-the lysosome
I-cell disease - ANSWER✔✔-Symptoms: Coarse facial features, {{clouded corneas,
restricted joint movement,}} high plasma levels of lysosomal enzymes. Fatal in
childhood.
Lab Values: {{Lysosomal enzymes secreted outside the cell; ghost lysosomes.}}
COPYRIGHT © 2025 BY OLIVIA GREENWAYS, ALL RIGHTS RESERVED 2
100% Solved Correct
Hereditary Fructose Intolerance - ANSWER✔✔-Aldolase B deficiency.
Symptoms: vomiting and hypoglycemia when fructose introduced to diet. Failure to
thrive, jaundice, and hepatomegaly.
1g of protein or carbohydrate = ? kcal
1g of fat = ? kcal - ANSWER✔✔-protein & carbs = 4 calories
fat = 9 calories
Wernicke-Korsakoff syndrome - ANSWER✔✔-Organic brain syndrome resulting from
prolonged heavy alcohol use, involving confusion, unintelligible speech, and loss of
motor coordination. It may be caused by a deficiency of *thiamine*, a vitamin
metabolized poorly by heavy drinkers.
Diarrhea, dementia, and dermatitis are indicative of what disease? What enzymes are
impaired? - ANSWER✔✔-pellagra - caused by niacin (B3) deficiency. Enzymes
impaired are the dehydrogenases.
COPYRIGHT © 2025 BY OLIVIA GREENWAYS, ALL RIGHTS RESERVED 1
, What enzymes are encoded by the lac operon? - ANSWER✔✔-beta-galactosidase,
permease, and transacetylase
classic example of polycistronic mRNA - ANSWER✔✔-the lac operon in E. coli
Beriberi - ANSWER✔✔-Thiamine (B1) deficiency. Causes peripheral neuropathy,
cardiomyopathy, high-output CHF, peripheral edema, and tachycardia. (Wet beriberi
includes the cardiac symptoms)
The ammonia buffer system helps to eliminate excess hydrogen ions by - ANSWER✔✔-
metabolism of glutamine to glutamate in renal tubular cells, generating ammonium that
is excreted in the urine
Which dietary sugar is metabolized the fastest? - ANSWER✔✔-Fructose.
Phosphorylated in the liver to F-1-P, which bypasses the RLS of PFK-1 in glycolysis.
Tagging with phosphorylated mannose residues marks proteins for delivery to... -
ANSWER✔✔-the lysosome
I-cell disease - ANSWER✔✔-Symptoms: Coarse facial features, {{clouded corneas,
restricted joint movement,}} high plasma levels of lysosomal enzymes. Fatal in
childhood.
Lab Values: {{Lysosomal enzymes secreted outside the cell; ghost lysosomes.}}
COPYRIGHT © 2025 BY OLIVIA GREENWAYS, ALL RIGHTS RESERVED 2
