GCU BIO 483 Pathophysiology Exam
questions with correct answers
What |causes |a |decreases/shrinkage |in |cellular |size? |- |VERIFIED |ANSWER✔✔-Atrophy
What |causes |a |increase |in |size |of |cells |(organ)? |- |VERIFIED |ANSWER✔✔-Hypertrophy
What |causes |a |increase |in |number |of |cells? |- |VERIFIED |ANSWER✔✔-Hyperplasia
What |causes |the |replacement |of |one |mature |cell |type |by |another |(Epithelium |changes |in |smokers)? |- |
VERIFIED |ANSWER✔✔-Metaplasia
What |causes |abnormal |change |in |size, |shape |and |organization |of |mature |cells |(cervical |cancer)? |- |
VERIFIED |ANSWER✔✔-Dysplasia
1. |Defects |in |membrane |permeability
2. |ATP |depletion
| • |No |energy
3. |Increases |in |intracellular |calcium
4. |Activate |enzymes |that |attack |cell |membranes.
5. |Free |radicals
| • |Highly |reactive
| • |Disrupts |pathways |- |VERIFIED |ANSWER✔✔-Mechanisms |of |Cell |Injury
1. |Hypoxic |Injury
2. |Reactive |oxygen |species |injury
3. |Chemical |injury
4. |Injury |related |to |immunologic/inflammatory |responses |- |VERIFIED |ANSWER✔✔-Cellular |Insult |
Overview
, What |causes |decrease |in |oxygen |to |cells |- |VERIFIED |ANSWER✔✔-Hypoxia
What |causes |Interrupts |oxidative |metabolism
| • |Anaerobic |respiration |takes |over
| • |More |or |less |ATP |produced? |- |VERIFIED |ANSWER✔✔-Hypoxia
Sodium-Potassium |pump |fails |with |____________ |in |ATP |production |swelling/edema |occurs. |- |
VERIFIED |ANSWER✔✔-Decrease
What |causes |pH |to |decreases? |- |VERIFIED |ANSWER✔✔-Increase |in |lactic |acid
What |causes |cell |becomes |'leaky' |and |internal |enzymes |get |into |circulation? |- |VERIFIED |ANSWER✔✔-
Hypoxia
What |internal |enzymes |can |be |measured |in |lab |tests |to |estimate |cellular |damage? |- |VERIFIED |
ANSWER✔✔-Hypoxia
What |are |the |following |examples |of?
• |Free |radical |production |
• |Lipid |peroxidation
• |Denatures |proteins
• |Genetic |mutations
• |Damages |mitochondria |- |VERIFIED |ANSWER✔✔-Reactive |Oxygen |Species
What |are |the |following |examples |of?
• |Injure |cell |membrane |and |increased |permeability
• |Block |enzymatic |pathways |by |abnormal |binding
• |Form |free |radicals. |- |VERIFIED |ANSWER✔✔-Damaged |Cell |Structures
questions with correct answers
What |causes |a |decreases/shrinkage |in |cellular |size? |- |VERIFIED |ANSWER✔✔-Atrophy
What |causes |a |increase |in |size |of |cells |(organ)? |- |VERIFIED |ANSWER✔✔-Hypertrophy
What |causes |a |increase |in |number |of |cells? |- |VERIFIED |ANSWER✔✔-Hyperplasia
What |causes |the |replacement |of |one |mature |cell |type |by |another |(Epithelium |changes |in |smokers)? |- |
VERIFIED |ANSWER✔✔-Metaplasia
What |causes |abnormal |change |in |size, |shape |and |organization |of |mature |cells |(cervical |cancer)? |- |
VERIFIED |ANSWER✔✔-Dysplasia
1. |Defects |in |membrane |permeability
2. |ATP |depletion
| • |No |energy
3. |Increases |in |intracellular |calcium
4. |Activate |enzymes |that |attack |cell |membranes.
5. |Free |radicals
| • |Highly |reactive
| • |Disrupts |pathways |- |VERIFIED |ANSWER✔✔-Mechanisms |of |Cell |Injury
1. |Hypoxic |Injury
2. |Reactive |oxygen |species |injury
3. |Chemical |injury
4. |Injury |related |to |immunologic/inflammatory |responses |- |VERIFIED |ANSWER✔✔-Cellular |Insult |
Overview
, What |causes |decrease |in |oxygen |to |cells |- |VERIFIED |ANSWER✔✔-Hypoxia
What |causes |Interrupts |oxidative |metabolism
| • |Anaerobic |respiration |takes |over
| • |More |or |less |ATP |produced? |- |VERIFIED |ANSWER✔✔-Hypoxia
Sodium-Potassium |pump |fails |with |____________ |in |ATP |production |swelling/edema |occurs. |- |
VERIFIED |ANSWER✔✔-Decrease
What |causes |pH |to |decreases? |- |VERIFIED |ANSWER✔✔-Increase |in |lactic |acid
What |causes |cell |becomes |'leaky' |and |internal |enzymes |get |into |circulation? |- |VERIFIED |ANSWER✔✔-
Hypoxia
What |internal |enzymes |can |be |measured |in |lab |tests |to |estimate |cellular |damage? |- |VERIFIED |
ANSWER✔✔-Hypoxia
What |are |the |following |examples |of?
• |Free |radical |production |
• |Lipid |peroxidation
• |Denatures |proteins
• |Genetic |mutations
• |Damages |mitochondria |- |VERIFIED |ANSWER✔✔-Reactive |Oxygen |Species
What |are |the |following |examples |of?
• |Injure |cell |membrane |and |increased |permeability
• |Block |enzymatic |pathways |by |abnormal |binding
• |Form |free |radicals. |- |VERIFIED |ANSWER✔✔-Damaged |Cell |Structures