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HESI A2 Vocabulary & General Knowledge Study Guide – 80 Practice Questions with Answers & Explanations

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Master the Vocabulary and General Knowledge section of the HESI A2 Admission Assessment Exam with this comprehensive study guide containing 80 carefully selected practice questions. Focuses on commonly tested vocabulary, medical terminology, word meanings, and general language skills. Each question includes detailed answers and explanations—ideal for nursing school applicants aiming to improve their language proficiency and test readiness.

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HESI A2 Vocabulary and General Knowledge
Practice Questions for Nursing Students

80 High-Quality Multiple-Choice Questions with Answers

Perfect for HESI A2 Exam Preparation




Designed for Stuvia Study Resources

Updated May 2025

, HESI A2 Vocabulary and General Knowledge Practice


Instructions
This document contains 80 HESI A2-style Vocabulary and General Knowledge multiple-
choice questions to prepare nursing students for the exam. Each question tests word
definitions, synonyms, or usage in context, focusing on medical, scientific, and health-
related terms. Select the best answer from the four options (A–D). The correct answer
is provided after each question for self-assessment.

Question Set 1 Question Set 1
Question 1: What does the word prognosis mean in a medical context?
A. A surgical procedure
B. A prediction of disease outcome
C. A type of medication
D. A diagnostic test
Correct Answer: B
Question 2: Choose the synonym for acute when describing a medical condition.
A. Chronic
B. Mild
C. Sudden
D. Preventable
Correct Answer: C
Question 3: In the sentence, The patients condition deteriorated rapidly, what does de-
teriorated mean?
A. Improved
B. Worsened
C. Stabilized
D. Changed
Correct Answer: B
Question 4: What is the definition of pathogen?
A. A nutrient
B. A disease-causing microorganism
C. A medical tool
D. A vaccine
Correct Answer: B



Page 1 of 17

, HESI A2 Vocabulary and General Knowledge Practice


Question Set 2 Question Set 2
Question 1: What does benign mean in relation to a tumor?
A. Cancerous
B. Non-cancerous
C. Infectious
D. Chronic
Correct Answer: B
Question 2: Choose the synonym for edema in a medical context.
A. Swelling
B. Fracture
C. Infection
D. Pain
Correct Answer: A
Question 3: In the sentence, The nurse administered the medication to alleviate pain,
what does alleviate mean?
A. Increase
B. Relieve
C. Cause
D. Measure
Correct Answer: B
Question 4: What is the definition of hypertension?
A. Low blood pressure
B. High blood pressure
C. Low blood sugar
D. High cholesterol
Correct Answer: B

Question Set 3 Question Set 3
Question 1: What does etiology mean in a medical report?
A. Treatment plan
B. Cause of a disease
C. Patients symptoms


Page 2 of 17

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