ABRAM’S CLINICAL DRUG THERAPY RATIONALES FOR NURSING PRACTICE 13th EDITION GERALYN FRANDSEN’S TESTBANK/COMPLETE GUIDE /ALL CHAPTERS 1-61

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,Chapter 1, The Foundation of Pharmacology: Quality and Safety
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1. A woman diagnosed with obsessive–
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compulsive disorder has been prescribed oral paroxetine hydrochloride. What is
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the expected effect for this prescription?
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A. Curative effect on symptoms xc x c xc



B. Systemic effect on symptoms xc xc xc



C. Local effect on symptoms xc xc xc



D. Parenteral effect on symptoms xc xc xc




ANS: B x c x c



Rationale: Drugs that produce systemic effects are taken into the body, circulated
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throug h the bloodstream to their sites of action in various body tissues, and
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eventually eliminat ed from the body. Curative agents are given to cure a disease process. In
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this case, paro xetine hydrochloride will control the symptoms but not cure the disorder.
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Drugs with loca l effects, such as sunscreen and local anesthetics, act mainly at the site of
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application. Pa roxetine hydrochloride is not administered parenterally. Parenteral agents
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are administere d subcutaneously, intramuscularly, or intravenously.
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PTS: 1 REF: p. 3, Introduction OBJ: 1 xc x c



NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral
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Therapi es TOP: Chapter: 1: The Foundation of Pharmacology: Quality and
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Safety KEY: Integrated Process: Nursing Process
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BLM: Cognitive Level: Understand
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2. A client has been prescribed an antibiotic. This medication is a naturally occurring
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substance that has been cheG
mRicAalDlyEm
SoBdOifOieSd.TW
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.hCaOt Mi s another name for this type
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o f medication?
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A. Synthetic drug xc



B. Semisynthetic drug xc



C. Biotechnology drug xc



D. Prototype drug xc




ANS: B x c x c



Rationale: Semisynthetic drugs (e.g., many antibiotics) are naturally occurring substances
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that have been chemically modified. Synthetic drugs are more standardized in their chemi cal
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characteristics, more consistent in their effects, and less likely to produce allergic rea
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ctions. Biotechnology drugs involve manipulating DNA and RNA and recombining gene
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s into hybrid molecules that can be inserted into living organisms. Prototype drugs are th
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e first drug of a particular group to be developed.
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PTS: 1 REF: p. 3, Drug Sources OBJ: 1 xc xc xc



NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral
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Therapi es TOP: Chapter: 1: The Foundation of Pharmacology: Quality and
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Safety KEY: Integrated Process: Nursing Process
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BLM: Cognitive Level: Understand
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3. Which classification applies to morphine?
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A. Central nervous system depressant xc xc xc



B. Central nervous system stimulant xc xc xc

, C. Anti-inflammatory
D. Antihypertensive
ANS: A x c x c



Rationale: Drugs are classified according to their effects on particular body systems,
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thei r therapeutic uses, and their chemical characteristics. Morphine is classified as a
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central nervous system depressant and will produce this effect in the client. A
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central nervous s ystem stimulant increases attention and raises mood. An anti-
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inflammatory agent decreases inflammation at the site of tissue or joint inflammation. An
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antihypertensive agent reduces blood pressure.
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PTS: 1 REF:
p. 3, Drug Classifications and Prototypes OBJ: 1
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NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral
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Therapi es TOP: Chapter: 1: The Foundation of Pharmacology: Quality and
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Safety KEY: Integrated Process: Nursing Process
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BLM: Cognitive Level: Remember x c NOT: Multiple Choice
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4. A client is administered amoxicillin. The generic name of this medication belongs to whi
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ch drug group?
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A. Selective serotonin reuptake inhibitors xc xc xc



B. Diuretics
C. Penicillins
D. ACE inhibitors xc




ANS: C x c x c



Rationale: The generic n a mGeR oAfD
t eEn Si nBdOicOa tSe T
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t hCe Od r u g group (e.g., drugs with generic
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na mes ending in ―cillin‖ are penicillins). Selective serotonin reuptake inhibitors are
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medicat
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ions that have antidepressant effects; SSRI is a broad classification, not a generic name. D
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iuretics are medications that increase urine output; diuretic is a broad classification, not a
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generic name. ACE inhibitor is the broad classification for the angiotensin receptor block ers,
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not the generic name.
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PTS: 1 REF: p. 3, Drug Names OBJ: 2 xc xc xc



NAT: Client Needs: Physiological Integrity: Pharmacological and Parenteral
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Therapi es TOP: Chapter: 1: The Foundation of Pharmacology: Quality and
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Safety KEY: Integrated Process: Nursing Process
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BLM: Cognitive Level: Understand
x c NOT: Multiple Choice
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5. The administration of diphenhydramine is regulated by which U.S. government agency?
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A. Public Health Service xc xc



B. Federal Trade Commission xc xc



C. Occupational Safety and Health Administration xc xc xc xc



D. Food and Drug xc x c




Administration ANS:
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