PHA 241 Exam 4 – Anemia QUESTIONS AND ASNWERS
YEAR 2025.
Decrease in the number, size or hemoglobin content of erythrocytes. - ✅✅Anemia
Deficiencies of Iron, folic acid or vitamin B 12 - ✅✅Causes of anemia
Meats, green leafy vegetables, grains and egg yolks are a good source of - ✅✅Iron
An increase or decrease in iron increases ferritin and decrease in transferin receptor -
✅✅Increase
An increase or decrease in iron decreases ferritin and increase in transferin receptor -
✅✅Decrease
Mechanism of iron elimination - ✅✅None
This protein protects cell from extra iron - ✅✅Ferritin
Trace amounts of this (1mg/day) are found in bile, urine, sweat, intestinal cells -
✅✅Iron
First step of iron absorption involves - ✅✅Oxidation
Iron absorbed best in acid or base? - ✅✅Acid
Fe3+ also known as - ✅✅Ferritin
This results in reduced oxygen-carry capacity - ✅✅Iron deficient anemia
Normal Iron levels - ✅✅60-170 mg/dL
<60 mg/dL Iron - ✅✅Anemia
Characteristics of anemic erythrocytes - ✅✅Microcytic, hypochromic - small and pale
An absence of hemosiderin is indicative of what disease state? - ✅✅Anemia
Anemia can result in an increase or decrease in iron binding capacity? - ✅✅Increase
OTC minimal requirement of iron (actually needed, not what is available) -
✅✅120mg/day
, Treatment of mild anemia - ✅✅Increase dietary iron food
Best type of iron salt available - at least on a budget - ✅✅Ferrous sulfate
This type of iron has steady bioavailability and therefore reduced chance of toxicity, but
is very expensive - ✅✅Carbonyl iron (Feosol)
Iron dosing for chronic renal failure - ✅✅200mg/day
Side effects include stomach/abdominal pain; nausea; constipation; black & tarry
school, vomiting, diarrhea - ✅✅Oral iron
Iron formulation for ulcers - ✅✅Iron dextran - IV or IM
Iron formulation for chronic kidney disease - ✅✅Iron sucrose - IV
Iron formulation for CKD dialysis - ✅✅Sodium Ferric - IV
This iron dextran formulation is not used much anymore due to possible anaphylactic
reactions - ✅✅DexFerrum
Parenteral iron IV infusion that is convenient as it rquires only 2 doses 5-8 days apart -
✅✅Ferumoxytol (Feraheme)
Biggest side effect of parenteral iron - ✅✅Hypotension
Why is iron needed for CKD? - ✅✅Erythropoetin formation; RBC depletion
While most things seem to decrease iron absorption, this increases iron absorption -
✅✅Ascorbic acid
Iron decreases absorption of these three drug classes - ✅✅Quinolone antibiotics,
tetracyclines, thyroid drugs
IV treatment for iron overdose - ✅✅deferoxamine
Oral treatment for iron overdose - ✅✅Deferasirox
Charcoal will not work for iron overdose; but this will - ✅✅Carbonate (CO3 2-)
Dietary sources for this include liver, green vegetables, yeast, nuts, cereals and fruit -
✅✅Folic acid
YEAR 2025.
Decrease in the number, size or hemoglobin content of erythrocytes. - ✅✅Anemia
Deficiencies of Iron, folic acid or vitamin B 12 - ✅✅Causes of anemia
Meats, green leafy vegetables, grains and egg yolks are a good source of - ✅✅Iron
An increase or decrease in iron increases ferritin and decrease in transferin receptor -
✅✅Increase
An increase or decrease in iron decreases ferritin and increase in transferin receptor -
✅✅Decrease
Mechanism of iron elimination - ✅✅None
This protein protects cell from extra iron - ✅✅Ferritin
Trace amounts of this (1mg/day) are found in bile, urine, sweat, intestinal cells -
✅✅Iron
First step of iron absorption involves - ✅✅Oxidation
Iron absorbed best in acid or base? - ✅✅Acid
Fe3+ also known as - ✅✅Ferritin
This results in reduced oxygen-carry capacity - ✅✅Iron deficient anemia
Normal Iron levels - ✅✅60-170 mg/dL
<60 mg/dL Iron - ✅✅Anemia
Characteristics of anemic erythrocytes - ✅✅Microcytic, hypochromic - small and pale
An absence of hemosiderin is indicative of what disease state? - ✅✅Anemia
Anemia can result in an increase or decrease in iron binding capacity? - ✅✅Increase
OTC minimal requirement of iron (actually needed, not what is available) -
✅✅120mg/day
, Treatment of mild anemia - ✅✅Increase dietary iron food
Best type of iron salt available - at least on a budget - ✅✅Ferrous sulfate
This type of iron has steady bioavailability and therefore reduced chance of toxicity, but
is very expensive - ✅✅Carbonyl iron (Feosol)
Iron dosing for chronic renal failure - ✅✅200mg/day
Side effects include stomach/abdominal pain; nausea; constipation; black & tarry
school, vomiting, diarrhea - ✅✅Oral iron
Iron formulation for ulcers - ✅✅Iron dextran - IV or IM
Iron formulation for chronic kidney disease - ✅✅Iron sucrose - IV
Iron formulation for CKD dialysis - ✅✅Sodium Ferric - IV
This iron dextran formulation is not used much anymore due to possible anaphylactic
reactions - ✅✅DexFerrum
Parenteral iron IV infusion that is convenient as it rquires only 2 doses 5-8 days apart -
✅✅Ferumoxytol (Feraheme)
Biggest side effect of parenteral iron - ✅✅Hypotension
Why is iron needed for CKD? - ✅✅Erythropoetin formation; RBC depletion
While most things seem to decrease iron absorption, this increases iron absorption -
✅✅Ascorbic acid
Iron decreases absorption of these three drug classes - ✅✅Quinolone antibiotics,
tetracyclines, thyroid drugs
IV treatment for iron overdose - ✅✅deferoxamine
Oral treatment for iron overdose - ✅✅Deferasirox
Charcoal will not work for iron overdose; but this will - ✅✅Carbonate (CO3 2-)
Dietary sources for this include liver, green vegetables, yeast, nuts, cereals and fruit -
✅✅Folic acid
