Advanced Pharmacology Final Exam Review TESTS BANKS WITH ANSWERS A+ GRADE.
What is the recommended level of low-density lipoprotein cholesterol (LDL) for patients with known
coronary artery disease? - 100mg/dl or less.
What is the MOA of group IV anti-dysrhythmia drugs? - Depressing phase 4 depolarization and
lengthening phases 1 and 2 repolarization.
Which drug therapy should be used to lower the serum concentration of thyroid hormones and re-
establish eumetabolic state in a patient with Graves' disease? - Anti-thyroid drugs.
Which type of diuretic would be used for a stage I hypertension in a patient with renal insufficiency? -
Loop diuretic.
What drug should be considered as first-line therapy for a client with hypertension and heart failure? -
Enalapril (Vasotec)
Which drug is considered safe for hypertension treatment during pregnancy? - Methyldopa (Aldomet)
What drug will reduce afterload because it is an alpha-adrenergic blocker? - Prazosin (Minipress)
What is an expected effect of the use of a beta-adrenergic blocker to control angina? - Reduced force of
cardiac contraction.
What side effect should be monitored closely in the elderly when taking Metformin (Glucophage) for type
2 diabetes? - Lactic acidosis.
What is the primary role of cytochrome p-450 in the liver? - Deactivate and detoxify medications and
other substances.
What is a component of Vitamin K-dependent clotting factors? - Prothrombin
How are IV morphine and nitroglycerin beneficial in acute heart failure? - Decrease preload.
, What is the purpose of administering a vasodilating drug to a patient in heart failure? - Decrease afterload.
What are some contrindications for HMG-co A reductase inhibitors (statins)? - They cause myopathies,
especially at higher doses or in combination with certain drugs. They should never be used in patients
taking Warfarin (Coumadin).
Which drug can reduce serum LDL the most in patients with hyperlipidemia? - Lovastatin (Mevacor)
Which drug is contrindicated in a patient with Myasthena Gravis? - Procainamide (Pronestyl).
What action is most effective in decreasing the risk of hyperkalemia associated with the start of
angiotensin-converting enzyme inhibitor (ACEI) therapy? - Making sure that the patient is well hydrated.
What factor influences plasma protein drug binding and distribution of that drug? - The amount of
albumin available in the blood stream.
What does the half-life of a medication determine? - How often the drug is to be administered.
What important information should be given to a patient who is taking Metoprolol (Lopressor) for angina
and hypertension? - The drug should not be taken with milk or dairy products.
Which medications should be avoided for patients with a sulfa allergy? - Sulfamethoxazole/Trimethoprim
(Bactrim) and Celecoxib (Celebrex).
What should be taken into consideration when prescribing fat-soluable drugs in the elderly? - They are
associated with increased duration of drug action.
Which hypolipidemic class of drugs does not have to have liver function studies? -
Hydroxymethylglutaryl-coenzyme A reductase inhibitors (statins)
FYI: I actually just looked this up because it didn't seem right...From the FDA: "The good news—no
more periodic blood tests for liver function. The warnings—taking a statin may increase the odds of
developing type 2 diabetes or suffering reversible memory loss or problems thinking. The FDA warned
What is the recommended level of low-density lipoprotein cholesterol (LDL) for patients with known
coronary artery disease? - 100mg/dl or less.
What is the MOA of group IV anti-dysrhythmia drugs? - Depressing phase 4 depolarization and
lengthening phases 1 and 2 repolarization.
Which drug therapy should be used to lower the serum concentration of thyroid hormones and re-
establish eumetabolic state in a patient with Graves' disease? - Anti-thyroid drugs.
Which type of diuretic would be used for a stage I hypertension in a patient with renal insufficiency? -
Loop diuretic.
What drug should be considered as first-line therapy for a client with hypertension and heart failure? -
Enalapril (Vasotec)
Which drug is considered safe for hypertension treatment during pregnancy? - Methyldopa (Aldomet)
What drug will reduce afterload because it is an alpha-adrenergic blocker? - Prazosin (Minipress)
What is an expected effect of the use of a beta-adrenergic blocker to control angina? - Reduced force of
cardiac contraction.
What side effect should be monitored closely in the elderly when taking Metformin (Glucophage) for type
2 diabetes? - Lactic acidosis.
What is the primary role of cytochrome p-450 in the liver? - Deactivate and detoxify medications and
other substances.
What is a component of Vitamin K-dependent clotting factors? - Prothrombin
How are IV morphine and nitroglycerin beneficial in acute heart failure? - Decrease preload.
, What is the purpose of administering a vasodilating drug to a patient in heart failure? - Decrease afterload.
What are some contrindications for HMG-co A reductase inhibitors (statins)? - They cause myopathies,
especially at higher doses or in combination with certain drugs. They should never be used in patients
taking Warfarin (Coumadin).
Which drug can reduce serum LDL the most in patients with hyperlipidemia? - Lovastatin (Mevacor)
Which drug is contrindicated in a patient with Myasthena Gravis? - Procainamide (Pronestyl).
What action is most effective in decreasing the risk of hyperkalemia associated with the start of
angiotensin-converting enzyme inhibitor (ACEI) therapy? - Making sure that the patient is well hydrated.
What factor influences plasma protein drug binding and distribution of that drug? - The amount of
albumin available in the blood stream.
What does the half-life of a medication determine? - How often the drug is to be administered.
What important information should be given to a patient who is taking Metoprolol (Lopressor) for angina
and hypertension? - The drug should not be taken with milk or dairy products.
Which medications should be avoided for patients with a sulfa allergy? - Sulfamethoxazole/Trimethoprim
(Bactrim) and Celecoxib (Celebrex).
What should be taken into consideration when prescribing fat-soluable drugs in the elderly? - They are
associated with increased duration of drug action.
Which hypolipidemic class of drugs does not have to have liver function studies? -
Hydroxymethylglutaryl-coenzyme A reductase inhibitors (statins)
FYI: I actually just looked this up because it didn't seem right...From the FDA: "The good news—no
more periodic blood tests for liver function. The warnings—taking a statin may increase the odds of
developing type 2 diabetes or suffering reversible memory loss or problems thinking. The FDA warned
