Basic and Clinical Pharmacology 16th Edition Katzung Trevor Test Bank
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FULL TESTBANK
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,Basic and Clinical Pharmacology 16th Edition Katzung Trevor Test Bank
Chapter 1. Introduction: The Nature of Drugs & Drug Development & Regulation
1. A nurse working in radiology administers iodine to a patient who is having a
computed tomography (CT) scan. The nurse working on the oncology unit
administers chemotherapy to patients who have cancer. At the Public Health
Department, a nurse administers a measles-mumps-rubella (MMR) vaccine to
a 14-month-old child as a routine immunization. Which branch of
pharmacology best describes the actions of all three nurses?
A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
Ans: B
Feedback:
Pharmacology is the study of the biologic effects of chemicals. Nurses are
involved with clinical pharmacology or pharmacotherapeutics, which is a
branch of pharmacology that deals with the uses of drugs to treat, prevent,
and diagnose disease. The radiology nurse is administering a drug to help
diagnose a disease. The oncology nurse is administering a drug to help treat a
disease. Pharmacoeconomics includes any costs involved in drug therapy.
Pharmacodynamics involves how a drug affects the body and
pharmacokinetics is how the body acts on the body.
2. A physician has ordered intramuscular (IM) injections of morphine, a
narcotic, every 4 hours as needed for pain in a motor vehicle accident victim.
The nurse is aware this drug has a high abuse potential. Under what category
would morphine be classified?
A) Schedule I
B) Schedule II
,C) Schedule III $xd
D) Schedule IV $xd
Ans: B
Feedback:
Narcotics with a high abuse potential are classified as Schedule II
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drugs because of severe dependence liability. Schedule I drugs have
$xd $xd $xd $xd $xd $xd $xd $xd $xd $xd
high abuse potential and no accepted medical use. Schedule III drugs
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have a lesser abuse potential than II and an accepted medical use.
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Schedule IV drugs have low abuse potential and limited dependence
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liability.
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3. When involved in phase III drug evaluation studies, what
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responsibilities would the nurse have?
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A) Working with animals who are given experimental drugs
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B) Choosing appropriate patients to be involved in the drug study
$xd $xd $xd $xd $xd $xd $xd $xd $ x d
C) Monitoring and observing patients closely for adverse effects
$xd $xd $xd $xd $xd $xd $ x d
D) Conducting research to determine effectiveness of the drug
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Ans: C
Feedback:
Phase III studies involve use of a drug in a vast clinical population in
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which patients are asked to record any symptoms they experience while
$xd $xd $xd $xd $xd $xd $xd $xd $xd $xd $xd
taking the drugs. Nurses may be responsible for helping collect and
$xd $xd $xd $xd $xd $xd $xd $xd $xd $xd $xd
analyze the information to be shared with the Food and Drug
$xd $xd $xd $xd $xd $xd $xd $xd $xd $xd $xd
Administration (FDA) but would not conduct research independently
$xd $xd $xd $xd $xd $xd $xd $xd
because nurses do not prescribe medications. Use of animals in drug
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testing is done in the preclinical trials. Select patients who are
$xd $xd $xd $xd $xd $xd $xd $xd $xd $xd $xd
involved in phase II studies to participate in studies where the
$xd $xd $xd $xd $xd $xd $xd $xd $xd $xd $xd
participants have the disease the drug is intended to treat. These
$xd $xd $xd $xd $xd $xd $xd $xd $xd $xd $xd
patients are monitored closely for drug action and adverse effects.
$xd $xd $xd $xd $xd $xd $xd $xd $xd $xd
Phase I studies involve healthy human volunteers who are usually paid
$xd $xd $xd $xd $xd $xd $xd $xd $xd $xd $xd
for their participation. Nurses may observe for adverse effects and
$xd $xd $xd $xd $xd $xd $xd $xd $xd $xd
toxicity.
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, 4. What concept is considered when generic drugs are substituted for
$xd $xd $xd $xd $xd $xd $xd $xd $xd
brand name drugs?
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A) Bioavailability
B) Critical concentration $xd
C) Distribution
D) Half-life
Ans: A
Feedback:
Bioavailability is the portion of a dose of a drug that reaches the $xd $xd $xd $xd $xd $xd $xd $xd $xd $xd $xd $xd
systemic circulation and is available to act on body cells. Binders
$xd $xd $xd $xd $xd $xd $xd $xd $xd $xd $xd
used in a generic drug may not be the same as those used in the
$xd $xd $xd $xd $xd $xd $xd $xd $xd $xd $xd $xd $xd $xd $xd
brand name drug. Therefore, the way the body breaks down and uses
$xd $xd $xd $xd $xd $xd $xd $xd $xd $xd $xd $xd
the drug may differ, which may eliminate a generic drug substitution.
$xd $xd $xd $xd $xd $xd $xd $xd $xd $xd $xd
Critical concentration is the amount of a drug that is needed to cause
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a therapeutic effect and should not differ between generic and brand
$xd $xd $xd $xd $xd $xd $xd $xd $xd $xd $xd
name medications. Distribution is the phase of pharmacokinetics,
$xd $xd $xd $xd $xd $xd $xd $xd
which involves the movement of a drug to the bodys tissues and is
$xd $xd $xd $xd $xd $xd $xd $xd $xd $xd $xd $xd $xd
the same in generic and brand name drugs. A drugs half-life is the
$xd $xd $xd $xd $xd $xd $xd $xd $xd $xd $xd $xd $xd
time it takes for the amount of drug to decrease to half the peak
$xd $xd $xd $xd $xd $xd $xd $xd $xd $xd $xd $xd $xd $xd
level, which should not change when substituting a generic
$xd $xd $xd $xd $xd $xd $xd $xd $xd
medication.
$ x d
5. A nurse is assessing the patients home medication use. After listening to
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the patient list current medications, the nurse asks what priority
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question?
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A) Do you take any generic medications?
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B) Are any of these medications orphan drugs?
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C) Are these medications safe to take during pregnancy?
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D) Do you take any over-the-counter medications?
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Ans: D
Feedback:
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FULL TESTBANK
$xd
,Basic and Clinical Pharmacology 16th Edition Katzung Trevor Test Bank
Chapter 1. Introduction: The Nature of Drugs & Drug Development & Regulation
1. A nurse working in radiology administers iodine to a patient who is having a
computed tomography (CT) scan. The nurse working on the oncology unit
administers chemotherapy to patients who have cancer. At the Public Health
Department, a nurse administers a measles-mumps-rubella (MMR) vaccine to
a 14-month-old child as a routine immunization. Which branch of
pharmacology best describes the actions of all three nurses?
A) Pharmacoeconomics
B) Pharmacotherapeutics
C) Pharmacodynamics
D) Pharmacokinetics
Ans: B
Feedback:
Pharmacology is the study of the biologic effects of chemicals. Nurses are
involved with clinical pharmacology or pharmacotherapeutics, which is a
branch of pharmacology that deals with the uses of drugs to treat, prevent,
and diagnose disease. The radiology nurse is administering a drug to help
diagnose a disease. The oncology nurse is administering a drug to help treat a
disease. Pharmacoeconomics includes any costs involved in drug therapy.
Pharmacodynamics involves how a drug affects the body and
pharmacokinetics is how the body acts on the body.
2. A physician has ordered intramuscular (IM) injections of morphine, a
narcotic, every 4 hours as needed for pain in a motor vehicle accident victim.
The nurse is aware this drug has a high abuse potential. Under what category
would morphine be classified?
A) Schedule I
B) Schedule II
,C) Schedule III $xd
D) Schedule IV $xd
Ans: B
Feedback:
Narcotics with a high abuse potential are classified as Schedule II
$xd $xd $xd $xd $xd $xd $xd $xd $xd $xd
drugs because of severe dependence liability. Schedule I drugs have
$xd $xd $xd $xd $xd $xd $xd $xd $xd $xd
high abuse potential and no accepted medical use. Schedule III drugs
$xd $xd $xd $xd $xd $xd $xd $xd $xd $xd $xd
have a lesser abuse potential than II and an accepted medical use.
$xd $xd $xd $xd $xd $xd $xd $xd $xd $xd $xd $xd
Schedule IV drugs have low abuse potential and limited dependence
$xd $xd $xd $xd $xd $xd $xd $xd $xd $xd
liability.
$xd
3. When involved in phase III drug evaluation studies, what
$xd $xd $xd $xd $xd $xd $xd $xd
responsibilities would the nurse have?
$xd $xd $xd $xd $xd
A) Working with animals who are given experimental drugs
$xd $xd $xd $xd $xd $xd $xd
B) Choosing appropriate patients to be involved in the drug study
$xd $xd $xd $xd $xd $xd $xd $xd $ x d
C) Monitoring and observing patients closely for adverse effects
$xd $xd $xd $xd $xd $xd $ x d
D) Conducting research to determine effectiveness of the drug
$xd $xd $xd $xd $xd $xd $xd
Ans: C
Feedback:
Phase III studies involve use of a drug in a vast clinical population in
$xd $xd $xd $xd $xd $xd $xd $xd $xd $xd $xd $xd $xd
which patients are asked to record any symptoms they experience while
$xd $xd $xd $xd $xd $xd $xd $xd $xd $xd $xd
taking the drugs. Nurses may be responsible for helping collect and
$xd $xd $xd $xd $xd $xd $xd $xd $xd $xd $xd
analyze the information to be shared with the Food and Drug
$xd $xd $xd $xd $xd $xd $xd $xd $xd $xd $xd
Administration (FDA) but would not conduct research independently
$xd $xd $xd $xd $xd $xd $xd $xd
because nurses do not prescribe medications. Use of animals in drug
$xd $xd $xd $xd $xd $xd $xd $xd $xd $xd $xd
testing is done in the preclinical trials. Select patients who are
$xd $xd $xd $xd $xd $xd $xd $xd $xd $xd $xd
involved in phase II studies to participate in studies where the
$xd $xd $xd $xd $xd $xd $xd $xd $xd $xd $xd
participants have the disease the drug is intended to treat. These
$xd $xd $xd $xd $xd $xd $xd $xd $xd $xd $xd
patients are monitored closely for drug action and adverse effects.
$xd $xd $xd $xd $xd $xd $xd $xd $xd $xd
Phase I studies involve healthy human volunteers who are usually paid
$xd $xd $xd $xd $xd $xd $xd $xd $xd $xd $xd
for their participation. Nurses may observe for adverse effects and
$xd $xd $xd $xd $xd $xd $xd $xd $xd $xd
toxicity.
$xd
, 4. What concept is considered when generic drugs are substituted for
$xd $xd $xd $xd $xd $xd $xd $xd $xd
brand name drugs?
$xd $xd $xd
A) Bioavailability
B) Critical concentration $xd
C) Distribution
D) Half-life
Ans: A
Feedback:
Bioavailability is the portion of a dose of a drug that reaches the $xd $xd $xd $xd $xd $xd $xd $xd $xd $xd $xd $xd
systemic circulation and is available to act on body cells. Binders
$xd $xd $xd $xd $xd $xd $xd $xd $xd $xd $xd
used in a generic drug may not be the same as those used in the
$xd $xd $xd $xd $xd $xd $xd $xd $xd $xd $xd $xd $xd $xd $xd
brand name drug. Therefore, the way the body breaks down and uses
$xd $xd $xd $xd $xd $xd $xd $xd $xd $xd $xd $xd
the drug may differ, which may eliminate a generic drug substitution.
$xd $xd $xd $xd $xd $xd $xd $xd $xd $xd $xd
Critical concentration is the amount of a drug that is needed to cause
$xd $xd $xd $xd $xd $xd $xd $xd $xd $xd $xd $xd $xd
a therapeutic effect and should not differ between generic and brand
$xd $xd $xd $xd $xd $xd $xd $xd $xd $xd $xd
name medications. Distribution is the phase of pharmacokinetics,
$xd $xd $xd $xd $xd $xd $xd $xd
which involves the movement of a drug to the bodys tissues and is
$xd $xd $xd $xd $xd $xd $xd $xd $xd $xd $xd $xd $xd
the same in generic and brand name drugs. A drugs half-life is the
$xd $xd $xd $xd $xd $xd $xd $xd $xd $xd $xd $xd $xd
time it takes for the amount of drug to decrease to half the peak
$xd $xd $xd $xd $xd $xd $xd $xd $xd $xd $xd $xd $xd $xd
level, which should not change when substituting a generic
$xd $xd $xd $xd $xd $xd $xd $xd $xd
medication.
$ x d
5. A nurse is assessing the patients home medication use. After listening to
$xd $xd $xd $xd $xd $xd $xd $xd $xd $xd $xd
the patient list current medications, the nurse asks what priority
$xd $xd $xd $xd $xd $xd $xd $xd $xd $xd
question?
$xd
A) Do you take any generic medications?
$xd $xd $xd $xd $xd
B) Are any of these medications orphan drugs?
$xd $xd $xd $xd $xd $xd
C) Are these medications safe to take during pregnancy?
$xd $xd $xd $xd $xd $xd $xd
D) Do you take any over-the-counter medications?
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Ans: D
Feedback:
