Med-Surg HESI Final Practice Questions 2025/2026 with accurate
and verified questions covering medical-surgical nursing concepts/
comprehensive test With Rationales A+ GRADE ASSURED //
BRAND NEW!!
The nurse is assessing a client's laboratory values following administration of
chemotherapy. Which lab value leads the nurse to suspect that the client is
experiencing tumor lysis syndrome (TLS)?
a. Serum PTT of 10 seconds.
b. Serum calcium of 5 mg/dL.
c. Oxygen saturation of 90%.
d. Hemoglobin of 10 g/dL - ✔✔ - B - Tumor lysis syndrome (TLS) results in
hyperkalemia, hypocalcemia, hyperuricemia, and hyperphosphatemia. A
serum calcium level of 5, which is low, is an indicator of possible tumor lysis
syndrome.
Which description of symptoms is characteristic of a client diagnosed with
trigeminal neuralgia (tic douloureux)?
a. Tinnitus, vertigo, and hearing difficulties.
b. Sudden, stabbing, severe pain over the lip and chin.
c. Facial weakness and paralysis.
d. Difficulty in chewing, talking, and swallowing. - ✔✔ - B - Trigeminal
neuralgia is characterized by paroxysms of pain, similar to an electric shock,
in the area innervated by one or more branches of the trigeminal nerve (5th
cranial). Women are more often afflicted with this condition and generally
occurs in clients over the age of 50 years old.
1|Page
,Which discharge instruction is most important for a client after a kidney
transplant?
a. Weigh weekly.
b. Report symptoms of secondary Candidiasis.
c. Use daily reminders to take immunosuppressants.
d. Stop cigarette smoking. - ✔✔ - C - After a renal transplantation, acute
rejection is a high risk for several months. The organ recipient will have to
take immunosuppressive therapy for the rest of their lives, such as
corticosteroids and azathioprine, to prevent organ transplant rejection.
Discharge instructions include measures such as daily reminders to ensure the
client takes these medications regularly to prevent organ rejection from
occurring.
A 58-year-old client who has been post-menopausal for five years is concerned
about the risk for osteoporosis because her mother has the condition. Which
information should the nurse offer?
a. Osteoporosis is a progressive genetic disease with no effective treatment.
b. Calcium loss from bones can be slowed by increasing calcium intake and
exercise.
c. Estrogen replacement therapy should be started to prevent the progression
osteoporosis.
d. Low-dose corticosteroid treatment effectively halts the course of osteoporosis. -
✔✔ - B - Post-menopausal females are at risk for osteoporosis due to the
cessation of estrogen secretion, but a regimen including calcium, vitamin D,
and weight-bearing exercise can help prevent further bone loss.
The nurse notes that the only ECG for a 55-year-old male client scheduled for
surgery in two hours is dated two years ago. The client reports that he has a history
of "heart trouble," but has no problems at present. Hospital protocol requires that
those over 50 years of age have a recent ECG prior to surgery. Which nursing
action is best for the nurse to implement?
2|Page
,a. Ask the client what he means by "heart trouble."
b. Call for an ECG to be performed immediately.
c. Notify surgery that the ECG is over two years old.
d. Notify the client's surgeon immediately. - ✔✔ - B
Which information about mammograms is most important to provide a post-
menopausal female client?
a. Breast self-examinations are not needed if annual mammograms are obtained.
b. Radiation exposure is minimized by shielding the abdomen with a lead-lined
apron.
c. Yearly mammograms should be done regardless of previous normal x-rays.
d. Women at high risk should have annual routine and ultrasound mammograms -
✔✔ - C - There are different recommendations from different agnecies. For a
client with no risk factors, the earliest breast screening recommendation is a
yearly mammogram at the age 40 and till the age of 54. After that every two
years. The American College of OB/GYN still recommend starting
mammograms starting at the age of 40 and yearly screeenings. The American
Cancer Society new guidelines recommend starting at the age of 45 and
thereafter till the age of 54 years old, then every two years. The US Preventive
Services Task Force Services (USPSTS) recommends starting at the age of 50
years old and screenings every two years thereafter.
The nurse is caring for a client with a continuous feeding through a percutaneous
endoscopic gastrostomy (PEG) tube. Which intervention should the nurse include
in the plan of care?
A. Flush the tube with 50 ml of water q 8 hours.
B. Check for tube placement and residual volume q4 hours.
C. Obtain a daily x- ray to verify tube placement.
3|Page
, D. Position on left side with head of bed elevated 45 degrees - ✔✔ - B -
Percutaneous endoscopic gastrostomy (PEG) tube placement and residual
volume should be checked every four hours for clients on continuous feeding.
If the gastric residual is more than 200mL for an adult client; stop the feeding
and re-check the gastric residual one hour later. If the residual still remains
more than 200mL; continue to keep the feeding on hold and contact the
client's health care provider.
The nurse is providing dietary instructions to a 68-year-old client who is at high
risk for development of coronary heart disease (CHD). Which information should
the nurse include?
a. Limit dietary selection of cholesterol to 300 mg per day.
b. Increase intake of soluble fiber to 10 to 25 grams per day.
c. Decrease plant stanols and sterols to less than 2 grams/day.
d. Ensure saturated fat is less than 30% of total caloric intake. - ✔✔ - B - To
reduce risk factors associated with coronary heart disease, the daily intake of
soluble fiber should be increased to between 10 and 25 grams per day.
According to the American Heart Association, soluble fibers helps reduce
LDL cholesterol levels.
Two days postoperative, a male client reports aching pain in his left leg. The nurse
assesses redness and warmth on the lower left calf. Which intervention would be
most helpful to this client?
a. Apply sequential compression devices (SCDs) bilaterally.
b. Assess for a positive Homan's sign in each leg.
c. Pad all bony prominences on the affected leg.
d. Advise the client to remain in bed with the leg elevated. - ✔✔ - D - For a client
exhibiting symptoms of deep vein thrombosis (DVT), a complication of
immobility, the initial care includes bedrest and elevation of the extremity.
4|Page
and verified questions covering medical-surgical nursing concepts/
comprehensive test With Rationales A+ GRADE ASSURED //
BRAND NEW!!
The nurse is assessing a client's laboratory values following administration of
chemotherapy. Which lab value leads the nurse to suspect that the client is
experiencing tumor lysis syndrome (TLS)?
a. Serum PTT of 10 seconds.
b. Serum calcium of 5 mg/dL.
c. Oxygen saturation of 90%.
d. Hemoglobin of 10 g/dL - ✔✔ - B - Tumor lysis syndrome (TLS) results in
hyperkalemia, hypocalcemia, hyperuricemia, and hyperphosphatemia. A
serum calcium level of 5, which is low, is an indicator of possible tumor lysis
syndrome.
Which description of symptoms is characteristic of a client diagnosed with
trigeminal neuralgia (tic douloureux)?
a. Tinnitus, vertigo, and hearing difficulties.
b. Sudden, stabbing, severe pain over the lip and chin.
c. Facial weakness and paralysis.
d. Difficulty in chewing, talking, and swallowing. - ✔✔ - B - Trigeminal
neuralgia is characterized by paroxysms of pain, similar to an electric shock,
in the area innervated by one or more branches of the trigeminal nerve (5th
cranial). Women are more often afflicted with this condition and generally
occurs in clients over the age of 50 years old.
1|Page
,Which discharge instruction is most important for a client after a kidney
transplant?
a. Weigh weekly.
b. Report symptoms of secondary Candidiasis.
c. Use daily reminders to take immunosuppressants.
d. Stop cigarette smoking. - ✔✔ - C - After a renal transplantation, acute
rejection is a high risk for several months. The organ recipient will have to
take immunosuppressive therapy for the rest of their lives, such as
corticosteroids and azathioprine, to prevent organ transplant rejection.
Discharge instructions include measures such as daily reminders to ensure the
client takes these medications regularly to prevent organ rejection from
occurring.
A 58-year-old client who has been post-menopausal for five years is concerned
about the risk for osteoporosis because her mother has the condition. Which
information should the nurse offer?
a. Osteoporosis is a progressive genetic disease with no effective treatment.
b. Calcium loss from bones can be slowed by increasing calcium intake and
exercise.
c. Estrogen replacement therapy should be started to prevent the progression
osteoporosis.
d. Low-dose corticosteroid treatment effectively halts the course of osteoporosis. -
✔✔ - B - Post-menopausal females are at risk for osteoporosis due to the
cessation of estrogen secretion, but a regimen including calcium, vitamin D,
and weight-bearing exercise can help prevent further bone loss.
The nurse notes that the only ECG for a 55-year-old male client scheduled for
surgery in two hours is dated two years ago. The client reports that he has a history
of "heart trouble," but has no problems at present. Hospital protocol requires that
those over 50 years of age have a recent ECG prior to surgery. Which nursing
action is best for the nurse to implement?
2|Page
,a. Ask the client what he means by "heart trouble."
b. Call for an ECG to be performed immediately.
c. Notify surgery that the ECG is over two years old.
d. Notify the client's surgeon immediately. - ✔✔ - B
Which information about mammograms is most important to provide a post-
menopausal female client?
a. Breast self-examinations are not needed if annual mammograms are obtained.
b. Radiation exposure is minimized by shielding the abdomen with a lead-lined
apron.
c. Yearly mammograms should be done regardless of previous normal x-rays.
d. Women at high risk should have annual routine and ultrasound mammograms -
✔✔ - C - There are different recommendations from different agnecies. For a
client with no risk factors, the earliest breast screening recommendation is a
yearly mammogram at the age 40 and till the age of 54. After that every two
years. The American College of OB/GYN still recommend starting
mammograms starting at the age of 40 and yearly screeenings. The American
Cancer Society new guidelines recommend starting at the age of 45 and
thereafter till the age of 54 years old, then every two years. The US Preventive
Services Task Force Services (USPSTS) recommends starting at the age of 50
years old and screenings every two years thereafter.
The nurse is caring for a client with a continuous feeding through a percutaneous
endoscopic gastrostomy (PEG) tube. Which intervention should the nurse include
in the plan of care?
A. Flush the tube with 50 ml of water q 8 hours.
B. Check for tube placement and residual volume q4 hours.
C. Obtain a daily x- ray to verify tube placement.
3|Page
, D. Position on left side with head of bed elevated 45 degrees - ✔✔ - B -
Percutaneous endoscopic gastrostomy (PEG) tube placement and residual
volume should be checked every four hours for clients on continuous feeding.
If the gastric residual is more than 200mL for an adult client; stop the feeding
and re-check the gastric residual one hour later. If the residual still remains
more than 200mL; continue to keep the feeding on hold and contact the
client's health care provider.
The nurse is providing dietary instructions to a 68-year-old client who is at high
risk for development of coronary heart disease (CHD). Which information should
the nurse include?
a. Limit dietary selection of cholesterol to 300 mg per day.
b. Increase intake of soluble fiber to 10 to 25 grams per day.
c. Decrease plant stanols and sterols to less than 2 grams/day.
d. Ensure saturated fat is less than 30% of total caloric intake. - ✔✔ - B - To
reduce risk factors associated with coronary heart disease, the daily intake of
soluble fiber should be increased to between 10 and 25 grams per day.
According to the American Heart Association, soluble fibers helps reduce
LDL cholesterol levels.
Two days postoperative, a male client reports aching pain in his left leg. The nurse
assesses redness and warmth on the lower left calf. Which intervention would be
most helpful to this client?
a. Apply sequential compression devices (SCDs) bilaterally.
b. Assess for a positive Homan's sign in each leg.
c. Pad all bony prominences on the affected leg.
d. Advise the client to remain in bed with the leg elevated. - ✔✔ - D - For a client
exhibiting symptoms of deep vein thrombosis (DVT), a complication of
immobility, the initial care includes bedrest and elevation of the extremity.
4|Page
